Immunological and pathological responses of red deer resistant or susceptible genotypes, to experimental challenge with Mycobacterium avium subsp. paratuberculosis

Veterinary Immunology and Immunopathology

Volumn 143, Issue 1-2, 2011, Pages 131-142

  Mackintosh, C G ^a   Clark, R G ^b   Tolentino, B ^a   De Lisle, G W ^c   Liggett, S ^d   Griffin, J F T ^d  

^a INVERMAY AGRICULTURAL CENTRE   (New Zealand)

^b AgResearch Wallaceville ^*  (New Zealand)

^c AGRESEARCH   (New Zealand)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Cervus elaphus; Heritable resistance; Immunology; Johne's disease; Mycobacterium avium subsp. paratuberculosis; Paratuberculosis; Pathology; Red deer

Indexed keywords

ANTIBODY; GAMMA INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; AUTOPSY; EUTHANASIA; FEMALE; GENOTYPE; HIND (RED DEER); HISTOPATHOLOGY; JEJUNUM BIOPSY; LYMPH NODE BIOPSY; MYCOBACTERIUM PARATUBERCULOSIS; NONHUMAN; PROGENY; RED DEER; SCORING SYSTEM;

ANIMALIA; CERVIDAE; CERVUS ELAPHUS; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS;

EID: 79961026587     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2011.06.035     Document Type: Article

References (38)

1. Allen A.J., Park K.T., Barrington G.M., Lahmers K.K., Hamilton M.J., Davis W.C. Development of a bovine ileal cannulation model to study the immune response and mechanisms of pathogenesis of paratuberculosis. Clin. Vaccine Immunol. 2009, 16:453-463.
2. Asher G.W., Fisher M.W., Fennessy P.F., Mackintosh C.G., Jabbour H.N., Morrow C.J. Oestrous synchronization, semen collection and artificial insemination of farmed red deer (Cervus elaphus) and fallow deer (Dama dama). Anim. Reprod. Sci. 1993, 33:241-265.
3. Attalla S.A., Seykora A.J., Cole J.B., Heins B.J. Genetic parameters of milk ELISA scores for Johne's disease. J. Dairy Sci. 2010, 93:1729-1735.
4. Berry D.P., Good M., Mullowney P., Cromie A.R., More S.J. Genetic variation in serological response to Mycobacterium avium subspecies paratuberculosis and its association with performance in Irish Holstein-Friesian dairy cows. Livestock Sci. 2010, 131:102-107.
5. Clark R.G., Griffin J.F.T., Mackintosh C.G. Johne's disease caused by Mycobacterium avium subsp. paratuberculosis infection in red deer (Cervus elaphus): an histopathological grading system, and comparison of paucibacillary and multibacillary disease. N. Z. Vet. J. 2010, 58:90-97.
6. de Lisle G.W., Yates G.F., Montgomery R.H. The emergence of Mycobacterium paratuberculosis in farmed deer in New Zealand - a review of 619 cases. N. Z. Vet. J. 2003, 51:58-62.
7. Dennis M.M., Reddacliff L.A., Whittington R.J. Longitudinal study of clinicopathological features of Johne's disease in sheep naturally exposed to Mycobacterium avium subspecies paratuberculosis. Vet. Pathol. 2010, 10.1177/0300985810375049.
8. Gilmour N.J.L., Angus K.W., Mitchell B. Intestinal infection and host response to oral administration of Mycobacterium johnei in sheep. Vet. Microbiol. 1977, 2:223-235.
9. Gonda M.G., Chang Y.M., Shook G.E., Collins M.T., Kirkpatrick B.W. Genetic variation of Mycobacterium avium ssp. paratuberculosis infection in US Holsteins. J. Dairy Sci. 2006, 89:1804-1812.
10. Griffin J.F.T., Cross J.P., Chinn D.N., Rogers C.R., Buchan G.S. Diagnosis of tuberculosis due to Mycobacterium bovis in New Zealand red deer (Cervus elaphus) using a composite blood test and antibody assays. N. Z. Vet. J. 1994, 42:173-179.
11. Griffin J.F.T., Rodgers C.R., Liggett S., Mackintosh C.G. Tuberculosis in ruminants: characteristics of intra-tonsilar Mycobacterium bovis infection models in cattle and deer. Tuberculosis 2006, 86:404-418.
12. Griffin J.F.T., Spittle E., Rodgers C.R., Liggett S., Cooper M., Bakker D., Bannantine J.P. Immunoglobulin G1 enzyme-linked immunosorbent assay for diagnosis of Johne's disease in red deer (Cervus elaphus). Clin. Diagn. Lab. Immunol. 2005, 12:1401-1409.
13. Hickey S.M., Morris C.A., Dobbie J.L., Lake D.E. Heritability of Johne's disease and survival data from Romney and Merino sheep. Proc. N. Z. Soc. Anim. Prod. 2003, 179-182.
14. Hinger M., Brandt H., Erhardt G. Heritability estimates for antibody response to Mycobacterium avium subspecies paratuberculosis in German holstein cattle. J. Dairy Sci. 2008, 91:3237-3244.
15. Khare S., Nunes J.S., Figueiredo J.F., Lawhon S.D., Rossetti C.A., Gull T., Rice-Ficht A.C., Adams L.G. Early phase morphological lesions and transcriptional responses of bovine ileum infected with Mycobacterium avium subsp. paratuberculosis. Vet. Pathol. 2009, 46:717-728.
16. Koets A.P., Adugna G., Janss L.L.G., van Weering H.J., Kalis C.H.J., Wentink G.H., Rutten V.P.M.G., Schukken Y.H. Genetic variation of susceptibility to Mycobacterium avium subsp. paratuberculosis infection in dairy cattle. J. Dairy Sci. 2000, 83:2702-2708.
17. Korou L.M., Liandris E., Gazouli M., Ikonomopoulos J. Investigation of the association of the SLC11A1 gene with resistance/sensitivity of goats (Capra hircus) to paratuberculosis. Vet. Microbiol. 2010, 144:353-358.
18. Mackintosh C.G. Epidemiology of Johne's disease in farmed red deer (Cervus elaphus) in New Zealand. Proc. N. Z. Soc. Anim. Prod. 2008, 68:117-121.
19. Mackintosh C.G., Clark R.G., Thompson B., Tolentino B., Griffin J.F.T., de Lisle G.W. Age susceptibility of red deer (Cervus elaphus) to paratuberculosis. Vet. Microbiol. 2010, 143:255-261.
20. Mackintosh C.G., de Lisle G.W., Collins D.M., Griffin J.F.T. Mycobacterial diseases of deer. N. Z. Vet. J. 2004, 52:163-174.
21. Mackintosh C.G., de Lisle G.W., Griffin J.F.T. Experimental challenge model for paratuberculosis in red deer. Proceedings of the 8th International Colloquium on Paratuberculosis 2006, 115-117.
22. Mackintosh C.G., Labes R.E., Clark R.G., de Lisle G.W., Griffin J.F.T. Experimental infections in young red deer (Cervus elaphus) with a bovine and an ovine strain of Mycobacterium avium subsp. paratuberculosis. N. Z. Vet. J. 2007, 55:23-29.
23. Mackintosh C.G., Labes R.E., Thompson B.R., Clark R.G., de Lisle G.W., Johnstone P.D., Griffin J.F.T. Efficacy, immune responses and side-effects of Johne's vaccines in young red deer (Cervus elaphus) experimentally challenged with Mycobacterium avium subsp. paratuberculosis. N. Z. Vet. J. 2008, 56:1-9.
24. Mackintosh C.G., Qureshi T., Waldrup K., Labes R.E., Dodds K.G., Griffin Genetic resistance to experimental infection with Mycobacterium bovis in red deer (Cervus elaphus). Infect. Immun. 2000, 68:1620-1625.
25. McConnel C.S., Churchill R.C., Richard M.M., Corkhill C.M., Reddacliff L.A., Whittington R.J. Surgical method for biopsy of terminal ileum and mesenteric lymph node of sheep for detection of Mycobacterium avium subsp. paratuberculosis. Aust. Vet. J. 2004, 82:149-151.
26. Morris C.A., Hickey S.M., Henderson H.V. The effect of Johne's disease on production traits in Romney, Merino and Merino×Romney-cross ewes. N. Z. Vet. J. 2006, 54:204-209.
27. Mortensen H., Nielsen S.S., Berg P. Genetic variation and heritability of the antibody response to Mycobacterium avium subspecies paratuberculosis in Danish Holstein cows. J. Dairy Sci. 2004, 87:2108-2113.
28. Osterstock J.B., Sinha S., Seabury C.M., Cohen N.D. Effect of classifying disease states in genetic association studies for paratuberculosis. Prev. Vet. Med. 2010, 95:41-49.
29. Pemberton D.H. Diagnosis of Johne's disease in cattle using mesenteric lymph node biopsy: accuracy in clinical suspects. Aust. Vet. J. 1979, 55:217-219.
30. Reddacliff L.A., Beh K., McGregor H., Whittington R.J. A preliminary study of possible genetic influences on the susceptibility of sheep to Johne's disease. Aust. Vet. J. 2005, 83:435-441.
31. Reddacliff L.A., Nicholls P.J., Vadali A., Whittington R.J. Use of growth indices from radiometric culture for quantification of sheep strains of Mycobacterium avium subsp paratuberculosis. Appl. Environ. Microbiol. 2003, 69:3510-3516.
32. Robinson M., O'Brien R., Mackintosh C., Griffin F. Differential immune responses of red deer (Cervus elaphus) following experimental challenge with Mycobacterium avium subsp. paratuberculosis. Clin. Vaccine Immunol. 2008, 15:963-969.
33. Sockett D.C., Carr D.J., Richards W.D., Collins M.T. A repository of specimens for comparison of diagnostic testing procedures for bovine paratuberculosis. J. Vet. Diagn. Invest. 1992, 4:188-191.
34. Stabel J.R. Host responses to Mycobacterium avium subsp. paratuberculosis: a complex arsenal. Anim. Health Res. Rev. 2006, 7:61-70.
35. Whitlock R.H., Wells S.J., Sweeney R.W., Van Tiem J. ELISA and fecal culture for paratuberculosis (Johne's disease): sensitivity and specificity of each method. Vet. Microbiol. 2000, 77:387-398.
36. Whittington R.J., Marsh I., McAllister S., Turner M.J., Marshall D.J., Fraser C.A. Evaluation of modified BACTEC 12B radiometric medium and solid media for culture of Mycobacterium avium subsp. paratuberculosis from sheep. J. Clin. Microbiol. 1999, 37:1077-1083.
37. Winslow G.M., Cooper A., Reiley W., Chatterjee M., Woodland D.L. Early T-cell responses in tuberculosis immunity. Immunol. Rev. 2008, 225:284-299.
38. Wu C.W., Livesey M., Schmoller S.K., Manning E.J., Steinberg H., Davis W.C., Hamilton M.J., Talaat A.M. Invasion and persistence of Mycobacterium avium subsp. paratuberculosis during early stages of Johne's disease in calves. Infect. Immun. 2007, 75:2110-2119.