Seven days of doxycycline is an effective treatment for asymptomatic rectal Chlamydia trachomatis infection

International Journal of STD and AIDS

Volumn 22, Issue 8, 2011, Pages 474-477

  Elgalib, A ^a   Alexander, S ^b   Tong, C Y W ^a   White, J A ^a  

^a GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Chlamydia trachomatis; Doxycycline; MSM; Rectal; Treatment

Indexed keywords

DOXYCYCLINE;

ADULT; ARTICLE; ASYMPTOMATIC DISEASE; CHLAMYDIASIS; CONTROLLED STUDY; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MALE HOMOSEXUAL; NUCLEIC ACID AMPLIFICATION; PRIORITY JOURNAL; RECTUM DISEASE; RISK; SEXUAL BEHAVIOR; TREATMENT OUTCOME; UNITED KINGDOM;

ADULT; ANTI-BACTERIAL AGENTS; ASYMPTOMATIC INFECTIONS; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; DOXYCYCLINE; FOLLOW-UP STUDIES; HOMOSEXUALITY, MALE; HUMANS; LONDON; MALE; RECTAL DISEASES; TREATMENT OUTCOME;

EID: 79960979280     PISSN: 09564624     EISSN: None     Source Type: Journal    
DOI: 10.1258/ijsa.2011.011134     Document Type: Article

References (19)

1. Benn PD, Rooney G, Carder C, et al. Chlamydia trachomatis and Neisseria gonorrhoeae infection and the sexual behaviour of men who have sex with men. Sex Transm Infect 2007;83:106-12
2. Centers for Disease Control and Prevention (CDC). Clinic-Based Testing for Rectal and Pharyngeal Neisseria gonorrhoeae and Chlamydia trachomatis Infections by Community-Based Organizations - Five Cities, United States, 2007. MMWR Morb Mortal Wkly Rep 2009;58:716-9
3. Jin F, Prestage G, Van de Ven P, et al. Prevalence, incidence and risk factors for syphilis, gonorrhoea and chlamydia in the Health In Men (HIM) Cohort. In: ASHM Conference Global Crisis: Local Action. Proceedings of the 15th annual ASHM Conference, Cairns, 22-25 October 2003. Cairns: Australian Society for HIV Medicine; 2003. p.96.
4. Lister NA, Smith A, Tabrizi S, et al. Screening for Neisseria gonorrhoeae and Chlamydia trachomatis in men who have sex with men at male-only saunas. Sex Transm Dis 2003;30:886-9
5. Ward H, Alexander S, Carder C, et al. The prevalence of lymphogranuloma venereum infection in men who have sex with men: results of a multicentre case finding study. Sex Transm Infect 2009;85:173-5
6. Annan NT, Sullivan AK, Nori A, et al. Rectal chlamydia - a reservoir of undiagnosed infection in men who have sex with men. Sex Transm Infect 2009;85:176-9
7. Dang T, Jaton-Ogay K, Flepp M, et al. High prevalence of anorectal chlamydial infection in HIV-infected men who have sex with men in Switzerland. Clin Infect Dis 2009;49:1532-5
8. Steedman NM, McMillan A. Treatment of asymptomatic rectal Chlamydia trachomatis: is single-dose azithromycin effective? Int J STD AIDS 2009;20:16-8
9. Fleming DT, Wasserheit JN. From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection. Sex Transm Infect 1999;75:3-17
10. Recommendations of the Advisory Committee for HIV and STD Prevention. HIV prevention through early detection and treatment of other sexually transmitted diseases - United States. MMWR Recomm Rep 1998;47:1-24
11. Joyee AG, Thyagarajan SP, Reddy EV, et al. Genital chlamydial infection in STD patients: its relation to HIV infection. Indian J Med Microbiol 2005;23:37-40
12. Ghys PD, Fransen K, Diallo MO, et al. The associations between cervicovaginal HIV shedding, sexually transmitted diseases and immunosuppression in female sex workers in Abidjan, Cote d'Ivoire. AIDS 1997;11:85-93
13. Bernstein KT, Marcus JL, Nieri G, et al. Rectal gonorrhea and Chlamydia reinfection is associated with increased risk of HIV seroconversion. J Acquir Immune Defic Syndr 2010;53:537-43
14. BASHH UK National Guideline for the Management of Genital Tract Infection with Chlamydia trachomatis. 2006. See http://www.bashh.org/documents/61/61.pdf (last accessed 18 March 2010)
15. De Vries HJ, Smelov V, Middelburg JG, et al. Delayed microbial cure of lymphogranuloma venereum proctitis with doxycycline treatment. Clin Infect Dis 2009;48:e53-e56
16. Chen CY, Chi KH, Alexander S, et al. The molecular diagnosis of lymphogranuloma venereum: evaluation of a real-time multiplex polymerase chain reaction test using rectal and urethral specimens. Sex Transm Dis 2007;34:451-5
17. McMillan A, Kell P, Ward H, British Co-operative Clinical Group of British Association for Sexual Health and HIV. Diagnosing chlamydia and managing proctitis in men who have sex with men: current UK practice. Sex Transm Infect 2008;84:97-100
18. Schachter J, Moncada J, Liska S, Shayevich C, Klausner. Nucleic acid amplification tests in the diagnosis of Chlamydia and gonococcal infections of the oropharynx and rectum of men who have sex with men. Sex Transm Dis 2008;35:637-42
19. Alexander S, Ison CA, Parry JV, et al. Self taken pharyngeal and rectal swabs are appropriate for the detection of chlamydia trachomatis and Neisseria gonorrhoeae in asymptomatic men who have sex with men. Sex Transm Infect 2008;84:488-92