Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 301, Issue 2, 2011, Pages

  Glaser, Shannon ^a,b,c   Gaudio, Eugenio ^e   Renzi, Anastasia ^b,e   Mancinelli, Romina ^e   Ueno, Yoshiyuki ^f   Venter, Julie ^b,c   White, Mellanie ^b,c   Kopriva, Shelley ^b   Chiasson, Valorie ^b   Demorrow, Sharon ^b,c   Francis, Heather ^b,c,d   Meng, Fanyin ^b,d   Marzioni, Marco ^g   Franchitto, Antonio ^e   Alvaro, Domenico ^e   Supowit, Scott ^h   Dipette, Donald J ^h   Onori, Paolo ⁱ   Alpini, Gianfranco ^a,b,c  

^a Texas A and M Health Sciences Center College of Medicine   (United States)

^b Texas A and M University   (United States)

^c SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^d TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

^f TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^h UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

Biliary epithelium; cAMP; Innervations; Mitosis; Sensory innervation

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; AMINOTRANSFERASE; BILIRUBIN; COLLAGEN TYPE 1; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA NUCLEOTIDYLEXOTRANSFERASE; INOSITOL; NEUROKININ 1 RECEPTOR;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BILE DUCT; BILE DUCT DISEASE; BILE DUCT HYPERPLASIA; BILIRUBIN BLOOD LEVEL; CELL COUNT; CELL DEATH; CELL PROLIFERATION; CELL TYPE; CHOLANGIOCYTE; CONTROLLED STUDY; HYPERPLASIA; IN VITRO STUDY; LIVER CELL; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STEATOSIS; UPREGULATION;

ACTINS; ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; BILE DUCTS; BILIRUBIN; CELL COUNT; CELL LINE; CELL PROLIFERATION; CHOLESTASIS; COLLAGEN TYPE I; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EPITHELIAL CELLS; HEPATOCYTES; INOSITOL 1,4,5-TRISPHOSPHATE; LIGATION; LIVER; MICE; MODELS, ANIMAL; NECROSIS; PHOSPHORYLATION; PROLIFERATING CELL NUCLEAR ANTIGEN; RECEPTORS, NEUROKININ-1; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUBSTANCE P;

EID: 79960977443     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00418.2010     Document Type: Article

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