High content-high throughput drug screening: Flow cytometry rises to meet the challenge

International Drug Discovery

Volumn 2011, Issue 3, 2011, Pages 10-14

  Robinson, J Paul ^a,b,d   Jo Davisson, V J ^c,d   Narayanan, Padmakumar ^e  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c PURDUE UNIVERSITY   (United States)

^d PURDUE UNIVERSITY   (United States)

^e AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOMATION; DATA ANALYSIS; DRUG SCREENING; FLOW CYTOMETRY; HIGH THROUGHPUT SCREENING; KNOWLEDGE BASE; QUALITY CONTROL; SCREENING;

EID: 79960975842     PISSN: 21504792     EISSN: 21504806     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Dean,PN, Bagwell,CB, Lindmo,T, Murphy,RC, and Salzman,GC; Data file standard for flow cytometry. Data File Standards Committee of the Society for Analytical Cytology, Cytometry 11:323-332, 1990.
2. Durack,G, Lawler,G, Kelley,S, Ragheb,K, Roth,RA, Ganey,P, and Robinson,JP; Time interval gating for analysis of cell function using flow cytometry, Cytometry 12:701-706, 1991
3. Murphy,RF and Chused,TM; A proposal for a flow cytometric data file standard, Cytometry 5:553-555, 1984
4. Nolan,GP; What's wrong with drug screening today, Nature Chemical Biology 3:187-191, 2007
5. Robinson,JP, Durack,G, and Kelley,S; An innovation in flow cytometry data collection & analysis producing a correlated multiple sample analysis in a single file, Cytometry 12:82-90, 1991
6. Seamer,LC, Bagwell,CB, Barden,L, Redelman,D, Salzman,GC, Wood,JC, and Murphy,RF; Proposed new data file standard for flow cytometry, version FCS 3.0, Cytometry 28:118-122, 1997.
7. Zanella,F, Lorens,JB, and Link,W; High content screening: seeing is believing, Trends in Biotechnology 28:237-245, 2011