Gene expression of WNTs, β-catenin and E-cadherin during the periimplantation period of pregnancy in pigs - involvement of steroid hormones

Theriogenology

Volumn 76, Issue 4, 2011, Pages 687-699

  Kiewisz, Jolanta ^a   Kaczmarek, Monika M ^a   Andronowska, Aneta ^a   Blitek, Agnieszka ^a   Ziecik, Adam J ^a  

^a INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

Author keywords

Pig; Pregnancy; Uterus; WNT

Indexed keywords

BETA CATENIN; CADHERIN; ESTRADIOL; PROGESTERONE; RNA; WNT PROTEIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIOSYNTHESIS; CHEMISTRY; ENDOMETRIUM; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; IN VITRO STUDY; NIDATION; NONPARAMETRIC TEST; PHYSIOLOGY; PREGNANCY; RANDOMIZATION; REAL TIME POLYMERASE CHAIN REACTION; SWINE; WESTERN BLOTTING;

ANIMALS; BETA CATENIN; BLOTTING, WESTERN; CADHERINS; EMBRYO IMPLANTATION; ENDOMETRIUM; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICROSCOPY, FLUORESCENCE; PREGNANCY; PROGESTERONE; RANDOM ALLOCATION; REAL-TIME POLYMERASE CHAIN REACTION; RNA; STATISTICS, NONPARAMETRIC; SWINE; WNT PROTEINS;

MOUSE MAMMARY TUMOR VIRUS; SUIDAE; SUS;

EID: 79960966073     PISSN: 0093691X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.theriogenology.2011.03.022     Document Type: Article

References (32)

1. Heikkila M., Peltoketo H., Vainio S. Wnts and the female reproductive system. J Exp Zool 2001, 290:616-623.
2. Sonderegger S., Pollheimer J., Knöfler M. Wnt signalling in implantation, decidualisation and placental differentiation-review. Placenta 2010, 31:839-847.
3. Miller C., Sassoon D.A. Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract. Development 1998, 125:3201-3211.
4. Mericskay M., Kitajewski J., Sassoon D. Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus. Development 2004, 131:2061-2072.
5. Hayashi K., Burghardt R.C., Bazer F.W., Spencer T.E. WNTs in the ovine uterus: potential regulation of periimplantation ovine conceptus development. Endocrinology 2007, 148:3496-3506.
6. Mohamed O.A., Jonnaert M., Labelle-Dumais C., Kuroda K., Clarke H.J., Dufort D. Uterine Wnt/beta-catenin signaling is required for implantation. Proc Natl Acad Sci U S A 2005, 102:8579-8584.
7. Herington J.L., Bi J., Martin J.D., Bany B.M. Beta-catenin (CTNNB1) in the mouse uterus during decidualization and the potential role of two pathways in regulating its degradation. J Histochem Cytochem 2007, 55:963-974.
8. Hou X., Tan Y., Li M., Dey S.K., Das S.K. Canonical Wnt signaling is critical to estrogen-mediated uterine growth. Mol Endocrinol 2004, 18:3035-3049.
9. Satterfield M.C., Dunlap K.A., Hayashi K., Burghardt R.C., Spencer T.E., Bazer F.W. Tight and adherens junctions in the ovine uterus: differential regulation by pregnancy and progesterone. Endocrinology 2007, 148:3922-3931.
10. Kim S., Choi Y., Bazer F.W., Spencer T.E. Identification of genes in the ovine endometrium regulated by interferon tau independent of signal transducer and activator of transcription 1. Endocrinology 2003, 144:5203-5214.
11. Bartol F.F., Wiley A.A., Bagnell C.A. Uterine development and endometrial programming. Soc Reprod Fertil Suppl 2006, 62:113-130.
12. Ryan P.L., Baum D.L., Lenhart J.A., Ohleth K.M., Bagnell C.A. Expression of uterine and cervical epithelial cadherin during relaxin-induced growth in pigs. Reproduction 2001, 122:929-937.
13. Ryan P.L., Valentine A.F., Bagnell C.A. Expression of epithelial cadherin in the developing and adult pig ovary. Biol Reprod 1996, 55:1091-1097.
14. Blitek A., Kiewisz J., Waclawik A., Kaczmarek M.M., Ziecik A.J. Effect of Steroids on HOXA10 mRNA and Protein Expression and Prostaglandin Production in the Porcine Endometrium. J Reprod Dev 2011, 56:643-648.
15. Ciereszko R.E., Opalka M., Kaminska B., Wojtczak M., Okrasa S., Dusza L. Luteotrophic action of prolactin during the early luteal phase in pigs: the involvement of protein kinases and phosphatases. Reproductive Biology 2001, 1:63-83.
16. Spagnuolo-Weaver M., Fuerst R., Campbell S.T., Meehan B.M., McNeilly F., Adair B., Allan G. A fluorimeter-based RT-PCR method for the detection and quantitation of porcine cytokines. J Immunol Methods 1999, 230:19-27.
17. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
18. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:48-254.
19. Stone B.A., Seamark R.F. Steroid hormones in uterine washings and in plasma of gilts between days 9 and 15 after oestrus and between days 9 and 15 after coitus. J Reprod Fertil 1985, 75:209-221.
20. Miller C., Pavlova A., Sasson D.A. Differential expression patterns of Wnt genes in the murine female reproductive tract during development and the estrous cycle. Mech Dev 1998, 76:91-99.
21. Hayashi K., Erikson D.W., Tilford S.A., Bany B.M., Maclean J.A., Rucker E.B., Johnson G.A., Spencer T.E. Wnt genes in the mouse uterus: potential regulation of implantation. Biol Reprod 2009, 80:989-1000.
22. Tulac S., Nayak N.R., Kao L.C., Van Waes M., Huang J., Lobo S., Germeyer A., Lessey B.A., Taylor R.N., Suchanek E., Giudice L.C. Identification, characterization, and regulation of the canonical Wnt signaling pathway in human endometrium. J Clin Endocrinol Metab 2003, 88:3860-3866.
23. Chen J.C., Wiley A.A., Ho T.Y., Frankshun A.L., Hord K.M., Bartol F.F., Bagnell C.A. Transient estrogen exposure from birth affects uterine expression of developmental markers in neonatal gilts with lasting consequences in pregnant adults. Reproduction 2010, 139:623-630.
24. Bui T.D., Zhang L., Rees M.C., Bicknell R., Harris A.L. Expression and hormone regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in normal human endometrium and endometrial carcinoma. Br J Cancer 1997, 75:1131-1136.
25. Waclawik A., Blitek A., Kaczmarek M.M., Kiewisz J., Ziecik A.J. Antiluteolytic mechanisms and the establishment of pregnancy in the pig. Soc Reprod Fertil Suppl 2009, 66:307-320.
26. Bischof R.J., Lee C.S., Brandon M.R., Meeusen E. Inflammatory response in the pig uterus induced by seminal plasma. J Reprod Immunol 1994, 26:131-146.
27. O'Leary S., Jasper M.J., Warnes G.M., Armstrong D.T., Robertson S.A. Seminal plasma regulates endometrial cytokine expression, leukocyte recruitment and embryo development in the pig. Reproduction 2004, 128:237-247.
28. Blumenthal A., Ehlers S., Lauber J., Buer J., Lange C., Goldmann T., Heine H., Brandt E., Reiling N. The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. Blood 2006, 108:965-973.
29. Blitek A., Kaczmarek M.M., Kiewisz J., Ziecik A.J. Endometrial and conceptus expression of HoxA10, transforming growth factor beta1, leukemia inhibitory factor, and prostaglandin H synthase-2 in early pregnant pigs with gonadotropin-induced estrus. Domest Anim Endocrinol 2010, 38:222-234.
30. Miller C., Degenhardt K., Sassoon D.A. Fetal exposure to DES results in de-regulation of Wnt7a during uterine morphogenesis. Nat Genet 1998, 20:228-230.
31. Gaetje R., Holtrich U., Karn T., Cikrit E., Engels K., Rody A., Kaufmann M. Characterization of WNT7A expression in human endometrium and endometriotic lesions. Fertil Steril 2007, 88:1534-1540.
32. van der Linden P.J., de Goeij A.F., Dunselman G.A., Erkens H.W., Evers J.L. Expression of cadherins and integrins in human endometrium throughout the menstrual cycle. Fertil Steril 1995, 63:1210-1216.