Discoidin domain receptor 1 is a major mediator of inflammation and fibrosis in obstructive nephropathy

American Journal of Pathology

Volumn 179, Issue 1, 2011, Pages 83-91

  Guerrot, Dominique ^a,b,c   Kerroch, Monique ^a,b   Placier, Sandrine ^a   Vandermeersch, Sophie ^a,b   Trivin, Claire ^a   Mael Ainin, Mouna ^a,b   Chatziantoniou, Christos ^a,b   Dussaule, Jean Claude ^a,b,d  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c ROUEN UNIVERSITY HOSPITAL   (France)

^d HÔPITAL SAINT ANTOINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DISCOIDIN DOMAIN RECEPTOR 1; FIBRILLAR COLLAGEN; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; HISTOPATHOLOGY; INTERSTITIAL NEPHRITIS; KIDNEY FIBROSIS; KIDNEY PARENCHYMA; LEUKOCYTE ADHERENCE; LEUKOCYTE ROLLING; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; URETER OBSTRUCTION;

ANIMALS; BLOTTING, WESTERN; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; FIBROSIS; HUMANS; INFLAMMATION; KIDNEY DISEASES; LEUKOCYTES; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 79960964827     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.03.023     Document Type: Article

References (70)

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31. B. Lange-Sperandio, K. Schimpgen, B. Rodenbeck, T. Chavakis, A. Bierhaus, P. Nawroth, B. Thornhill, F. Schaefer, and R. Chevalier Distinct roles of Mac-1 and its counter-receptors in neonatal obstructive nephropathy Kidney Int 69 2006 81 88
32. H. Anders, V. Vielhauer, M. Frink, Y. Linde, C. Cohen, S. Blattner, M. Kretzler, F. Strutz, M. Mack, H. Gröne, J. Onuffer, R. Horuk, P. Nelson, and D. Schlöndorff A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation J Clin Invest 109 2002 251 259
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34. M. Rincón, H. Enslen, J. Raingeaud, M. Recht, T. Zapton, M. Su, L. Penix, R. Davis, and R. Flavell Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway EMBO J 17 1998 2817 2829
35. C. Franco, P.J. Ahmad, G. Hou, E. Wong, and M.P. Bendeck Increased cell and matrix accumulation during atherogenesis in mice with vessel wall-specific deletion of discoidin domain receptor 1 Circ Res 106 2010 1775 1783
36. W.F. Vogel, R. Abdulhussein, and C.E. Ford Sensing extracellular matrix: an update on discoidin domain receptor function Cell Signal 18 2006 1108 1116 (Pubitemid 43674043)
37. R. Lee, K.E. Eidman, S.M. Kren, T.H. Hostetter, and Y. Segal Localization of discoidin domain receptors in rat kidney Nephron Exp Nephrol 97 2004 e62 e70
38. C.A. Curat, and W.F. Vogel Discoidin domain receptor 1 controls growth and adhesion of mesangial cells J Am Soc Nephrol 13 2002 2648 2656 (Pubitemid 35216033)
39. W. Vogel, G.D. Gish, F. Alves, and T. Pawson The discoidin domain receptor tyrosine kinases are activated by collagen Mol Cell 1 1997 13 23 (Pubitemid 127376389)
40. G. Hou, W.F. Vogel, and M.P. Bendeck Tyrosine kinase activity of discoidin domain receptor 1 is necessary for smooth muscle cell migration and matrix metalloproteinase expression Circ Res 90 2002 1147 1149 (Pubitemid 34786897)
41. G. Agarwal, C. Mihai, and D.F. Iscru Interaction of discoidin domain receptor 1 with collagen type 1 J Mol Biol 367 2007 443 455 (Pubitemid 46295432)
42. M. Jonsson, and T. Andersson Repression of Wnt-5a impairs DDR1 phosphorylation and modifies adhesion and migration of mammary cells J Cell Sci 114 2001 2043 2053 (Pubitemid 32586629)
43. C. Franco, G. Hou, P.J. Ahmad, E.Y.K. Fu, L. Koh, W.F. Vogel, and M.P. Bendeck Discoidin domain receptor 1 deletion decreases atherosclerosis by accelerating cell matrix accumulation and reducing inflammation in low-density lipoprotein receptor-deficient mice During Circ Res 102 2008 1202 1211
44. S. Das, P.P. Ongusaha, Y.S. Yang, J.M. Park, S.A. Aaronson, and S.W. Lee Discoidin domain receptor 1 receptor tyrosine kinase induces cyclooxygenase-2 and promotes chemoresistance through nuclear factor-kappaB pathway activation Cancer Res 66 2006 8123 8130 (Pubitemid 44299179)
45. H. Kamohara, S. Yamashiro, C. Galligan, and T. Yoshimura Discoidin domain receptor 1 isoform-a (DDR1alpha) promotes migration of leukocytes in three-dimensional collagen lattices FASEB J 15 2001 2724 2726
46. M. Flamant, S. Placier, A. Rodenas, C.A. Curat, W.F. Vogel, C. Chatziantoniou, and J.C. Dussaule Discoidin domain receptor 1 null mice are protected against hypertension-induced renal disease J Am Soc Nephrol 17 2006 3374 3381 (Pubitemid 44865280)
47. C. Avivi-Green, M. Singal, and W.F. Vogel Discoidin domain receptor 1-deficient mice are resistant to bleomycin-induced lung fibrosis Am J Respir Crit Care Med 174 2006 420 427 (Pubitemid 44223123)
48. G. Hou, W. Vogel, and M.P. Bendeck The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair J Clin Invest 107 2001 727 735 (Pubitemid 32225358)
49. K.K. Lu, D. Trcka, and M.P. Bendeck Collagen stimulates discoidin domain receptor 1-mediated migration of smooth muscle cells through Src Cardiovasc Pathol 20 2010 71 76
50. P.J. Ahmad, D. Trcka, S. Xue, C. Franco, M.Y. Speer, C.M. Giachelli, and M.P. Bendeck Discoidin domain receptor-1 deficiency attenuates atherosclerotic calcification and smooth muscle cell-mediated mineralization Am J Pathol 175 2009 2686 2696
51. W. Vogel, A. Aszódi, F. Alves, and T. Pawson Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development Mol Cell Biol 21 2001 2906 2917 (Pubitemid 32244933)
52. J. Boffa, P. Tharaux, S. Placier, R. Ardaillou, J. Dussaule, and C. Chatziantoniou Angiotensin II activates collagen type I gene in the renal vasculature of transgenic mice during inhibition of nitric oxide synthesis: evidence for an endothelin-mediated mechanism Circulation 100 1999 1901 1908 (Pubitemid 29511144)
53. C. Chatziantoniou, J. Boffa, R. Ardaillou, and J. Dussaule Nitric oxide inhibition induces early activation of type I collagen gene in renal resistance vessels and glomeruli in transgenic mice: role of endothelin J Clin Invest 101 1998 2780 2789 (Pubitemid 28294587)
54. O. Gross, B. Beirowski, S.J. Harvey, C. McFadden, D. Chen, S. Tam, P.S. Thorner, N. Smyth, K. Addicks, W. Bloch, Y. Ninomiya, Y. Sado, M. Weber, and W.F. Vogel DDR1-deficient mice show localized subepithelial GBM thickening with focal loss of slit diaphragms and proteinuria Kidney Int 66 2004 102 111 (Pubitemid 38870086)
55. W. Matsuyama, L. Wang, W.L. Farrar, M. Faure, and T. Yoshimura Activation of discoidin domain receptor 1 isoform b with collagen up-regulates chemokine production in human macrophages: role of p38 mitogen-activated protein kinase and NF-kappa B J Immunol 172 2004 2332 2340 (Pubitemid 38182381)
56. C. Hansen, P. Greengard, A. Nairn, T. Andersson, and W. Vogel Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1 Exp Cell Res 312 2006 4011 4018 (Pubitemid 44828046)
57. V. Heinzelmann-Schwarz, M. Gardiner-Garden, S. Henshall, J. Scurry, R. Scolyer, M. Davies, M. Heinzelmann, L. Kalish, A. Bali, J. Kench, L. Edwards, P. Vanden Bergh, N. Hacker, R. Sutherland, and P. O'Brien Overexpression of the cell adhesion molecules DDR1, Claudin 3, and Ep-CAM in metaplastic ovarian epithelium and ovarian cancer Clin Cancer Res 10 2004 4427 4436 (Pubitemid 38878885)
58. T. Yoshimura, W. Matsuyama, and H. Kamohara Discoidin domain receptor 1: a new class of receptor regulating leukocyte-collagen interaction Immunol Res 31 2005 219 230
59. L. Flynn, A. Blissett, E. Calomeni, and G. Agarwal Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2 J Mol Biol 395 2010 533 543
60. O. Gross, R. Girgert, B. Beirowki, M. Kretzler, H.G. Kang, J. Kruegel, N. Miosge, A.C. Busse, S. Segerer, W.F. Vogel, G.A. Muller, and M. Weber Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease Matrix Biol 29 2010 346 356
61. C. Chatziantoniou, and J.C. Dussaule Insights into the mechanisms of renal fibrosis: is it possible to achieve regression? Am J Physiol Renal Physiol 289 2005 F227 E234
62. R. Chevalier Specific molecular targeting of renal injury in obstructive nephropathy Kidney Int 70 2006 1200 1201 (Pubitemid 44435169)
63. R. Chevalier, M. Forbes, and B. Thornhill Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy Kidney Int 75 2009 1145 1152
64. V. Vielhauer, H. Anders, M. Mack, J. Cihak, F. Strutz, M. Stangassinger, B. Luckow, H. Gröne, and D. Schlöndorff Obstructive nephropathy in the mouse: progressive fibrosis correlates with tubulointerstitial chemokine expression and accumulation of CC chemokine receptor 2- and 5-positive leukocytes J Am Soc Nephrol 12 2001 1173 1187 (Pubitemid 32472630)
65. B. Lange-Sperandio, F. Cachat, B. Thornhill, and R. Chevalier Selectins mediate macrophage infiltration in obstructive nephropathy in newborn mice Kidney Int 61 2002 516 524 (Pubitemid 34102591)
66. B. Lange-Sperandio, K. Schimpgen, B. Rodenbeck, T. Chavakis, A. Bierhaus, P. Nawroth, B. Thornhill, F. Schaefer, and R. Chevalier Distinct roles of Mac-1 and its counter-receptors in neonatal obstructive nephropathy Kidney Int 69 2006 81 88 (Pubitemid 43117742)
67. H. Anders, V. Vielhauer, M. Frink, Y. Linde, C. Cohen, S. Blattner, M. Kretzler, F. Strutz, M. Mack, H. Gröne, J. Onuffer, R. Horuk, P. Nelson, and D. Schlöndorff A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation J Clin Invest 109 2002 251 259 (Pubitemid 34083745)
68. C. Franco, K. Britto, E. Wong, G. Hou, S.N. Zhu, M. Chen, M.I. Cybulsky, and M.P. Bendeck Discoidin domain receptor 1 on bone marrow-derived cells promotes macrophage accumulation during atherogenesis Circ Res 105 2009 1141 1148
69. M. Rincón, H. Enslen, J. Raingeaud, M. Recht, T. Zapton, M. Su, L. Penix, R. Davis, and R. Flavell Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway EMBO J 17 1998 2817 2829
70. C. Franco, P.J. Ahmad, G. Hou, E. Wong, and M.P. Bendeck Increased cell and matrix accumulation during atherogenesis in mice with vessel wall-specific deletion of discoidin domain receptor 1 Circ Res 106 2010 1775 1783