The mitochondrial A3243G mutation involves the peripheral vestibule as well as the cochlea

Laryngoscope

Volumn 121, Issue 8, 2011, Pages 1821-1824

  Iwasaki, Shinichi ^a   Egami, Naoya ^a   Fujimoto, Chisato ^a   Chihara, Yasuhiro ^a   Ushio, Munetaka ^a   Kashio, Akinori ^a   Yamasoba, Tatsuya ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

A3243G mutation; Mitochondrial DNA; sensorineural hearing loss; vestibular dysfunction; vestibular evoked myogenic potential

Indexed keywords

ADULT; AIR CONDUCTION; ARTICLE; CALORIC VESTIBULAR TEST; CLINICAL ARTICLE; COCHLEA; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE MUTATION; HEARING LOSS; HOSPITAL PATIENT; HUMAN; LACTIC ACIDOSIS; MALE; MELAS SYNDROME; MITOCHONDRIAL GENE; MITOCHONDRIAL MUTATION; ONSET AGE; PRIORITY JOURNAL; PROSPECTIVE STUDY; STIMULUS RESPONSE; STROKE; VESTIBULAR DISORDER; VESTIBULAR EVOKED MYOGENIC POTENTIAL; VESTIBULAR FUNCTION; VESTIBULAR STIMULATION; VESTIBULE;

ACOUSTIC STIMULATION; ADULT; AUDITORY THRESHOLD; BODY SURFACE POTENTIAL MAPPING; CALORIC TESTS; COCHLEA; DIABETES COMPLICATIONS; DNA, MITOCHONDRIAL; ELECTROMYOGRAPHY; FEMALE; HEARING LOSS, SENSORINEURAL; HUMANS; MALE; MELAS SYNDROME; MIDDLE AGED; MITOCHONDRIAL DISEASES; POINT MUTATION; VESTIBULAR DISEASES; VESTIBULAR EVOKED MYOGENIC POTENTIALS; VESTIBULAR FUNCTION TESTS;

EID: 79960958252     PISSN: 0023852X     EISSN: 15314995     Source Type: Journal    
DOI: 10.1002/lary.21879     Document Type: Article

References (21)

1. Wallace DC,. Diseases of mitochondrial DNA. Annu Rev Biochem 1992; 61: 1175-1212.
2. Kokotas H, Peterson MB, Willems PJ,. Mitochondrial deafness. Clin Genet 2007; 71: 379-391. (Pubitemid 46730646)
3. Gold M, Rapin I,. Non-Mendelian mitochondrial inheritance as a cause of progressive genetic sensorineural hearing loss. Int J Pediatr Otorhinolaryngol 1994; 30: 91-104. (Pubitemid 24183871)
4. Yamasoba T, Oka Y, Tsukuda K, Nakamura M, Kaga K,. Auditory findings in patients with maternally inherited diabetes and deafness harboring a point mutation in the mitochondrial transfer RNALeu (UUR) gene. Laryngoscope 1996; 106: 49-53.
5. Yamasoba T, Tsukuda K, Oka Y, Kobayashi T, Kaga K,. Cochlear histopathology associated with mitochondrial transfer RNALeu (UUR) gene mutation. Neurology 1999; 52: 1705-1707. (Pubitemid 29220655)
6. Sue CM, Lipsett LJ, Crimmins DS, et al. Cochlear origin of hearing loss in MELAS syndrome. Ann Neurol 1998; 43: 350-359. (Pubitemid 28113598)
7. Tamagawa Y, Kitamura K, Hagiwara H, et al. Audiologic findings in patients with a point mutation at nucleotide 3,243 of mitochondrial DNA. Ann Otol Rhinol Laryngol 1997; 106: 338-342. (Pubitemid 27175025)
8. Welgampola MS, Colebatch JG,. Characteristics and clinical application of vestibular-evoked myogenic potentials. Neurology 2005; 64: 1682-1688. (Pubitemid 40695798)
9. Colebatch JG, Halmagyi GM,. Vestibular evoked potentials in human neck muscles before and after unilateral vestibular deafferentation. Neurology 1992; 42: 1635-1636.
10. Watson SRD, Colebatch JG,. Vestibulocollic reflexes evoked by short-duration galvanic stimulation in man. J Physiol 1998; 513: 587-597. (Pubitemid 28562972)
11. Murofushi T, Takegoshi H, Ohki M, Ozeki H,. Galvanic-evoked myogenic responses in patients with an absence of click-evoked vestibulo-collic reflexes. Clin Neurophysiol 2002; 113: 305-309. (Pubitemid 34164717)
12. Hirano M, Ricci E, Koenigsberger MR, et al. MELAS: an original case and clinical criteria for diagnosis. Neuromuscul Disord 1992; 2: 125-135.
13. van den Ouweland JM, Lemkes HH, Trembath RC, et al. Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA (Leu(UUR)) gene. Diabetes 1994; 43: 746-751
14. Murofushi T, Matsuzaki M, Wu CH,. Short tone burst-evoked myogenic potentials on the sternocleidomastoid muscle: are these potentials also of vestibular origin? Arch Otolaryngol Head Neck Surg 1999; 125: 660-664. (Pubitemid 29269841)
15. Schmal F, Lubben B, Weiberg K, Stoll W,. The minimal ice water caloric test compared with established vestibular caloric test procedures. J Vestib Res 2005; 15: 215-224. (Pubitemid 41634841)
16. Fujimoto C, Murofushi T, Chihara Y, et al. Assessment of diagnostic accuracy of foam posturography for peripheral vestibular disorders: analysis of parameters related to visual and somatosensory dependence. Clin Neurophysiol 2009; 120: 1408-1414.
17. Wangemann P,. Comparison of ion transport mechanism between vestibular dark cells and strial marginal cells. Hear Res 1995; 90: 149-157.
18. Ciuman RR,. Stria vascularis and vestibular dark cells: characterization of main structures responsible for inner-ear homeostasis, and their pathophysiological relations. J Laryngol Otol 2009; 123: 151-162.
19. McCue MP, Guinan JJ Jr,. Acoustically responsive fibers in the vestibular nerve of the cat. J Neurosci 1994; 14: 6058-6070. (Pubitemid 24307798)
20. Murofushi T, Curthoys IS, Topple AN, Colebatch JG, Halmagyi GM,. Responses of guinea pig primary vestibular neurons to clicks. Exp Brain Res 1995; 103: 174-178.
21. Takahashi K, Merchant SN, Miyazawa T, et al. Temporal bone histopathological and quantitative analysis of mitochondrial DNA in MELAS. Laryngoscope 2003; 113: 1362-1628.