Are traditional NSAIDs prescribed appropriately among French elderly with osteoarthritis? Results from the CADEUS cohort

European Journal of Clinical Pharmacology

Volumn 67, Issue 8, 2011, Pages 833-838

  Gulmez, Sinem Ezgi ^a   Droz Perroteau, Cécile ^b   Lassalle, Régis ^a   Blin, Patrick ^a   Bégaud, Bernard ^a   Rossignol, Michel ^c   Moore, Nicholas ^a   Fourrier Réglat, Annie ^a  

^a BORDEAUX UNIVERSITY HOSPITAL   (France)

^b Centre of Clinical Investigation Clinical Epidemiology   (France)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Beers criteria; CADEUS; Elderly; Inappropriate prescribing; Non steroidal anti inflammatory drugs

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; ANTIVITAMIN K; DICLOFENAC; ETODOLAC; FLURBIPROFEN; IBUPROFEN; INDOMETACIN; KETOPROFEN; MELOXICAM; NAPROXEN; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PROTON PUMP INHIBITOR; TENOXICAM;

AGED; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INDICATION; DRUG MEGADOSE; DRUG MONITORING; ELDERLY CARE; ETHNIC GROUP; FEMALE; FRENCH LANGUAGE; HUMAN; INAPPROPRIATE PRESCRIBING; LONG TERM CARE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PRESCRIPTION; PRIORITY JOURNAL; RISK ASSESSMENT; TREATMENT DURATION;

AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; COHORT STUDIES; DICLOFENAC; DRUG INTERACTIONS; FEMALE; FRANCE; GUIDELINE ADHERENCE; HUMANS; INAPPROPRIATE PRESCRIBING; INSURANCE, HEALTH, REIMBURSEMENT; MALE; NATIONAL HEALTH PROGRAMS; OSTEOARTHRITIS; PIROXICAM; PLATELET AGGREGATION INHIBITORS; PRACTICE GUIDELINES AS TOPIC; PROSPECTIVE STUDIES; QUESTIONNAIRES;

EID: 79960955060     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-011-1015-6     Document Type: Article

References (17)

1. Moore N, Diris H, Martin K, Viale R, Fourrier A, Moride Y, Begaud B (2004) NSAID use profiles derived from reimbursement data in France. Therapie 59(5):541-546 (Pubitemid 40051547)
2. Depont F, Fourrier A, Merliere Y, Droz C, Amouretti M, Begaud B, Benichou J, Moride Y, Blin P, Moore N (2007) The CADEUS study: methods and logistics. Pharmacoepidemiol Drug Saf 16(5):571-580 (Pubitemid 46824279)
3. Depont F, Fourrier A, Merliere Y, Droz C, Amouretti M, Begaud B, Benichou J, Moride Y, Velo GP, Sturkenboom M, Blin P, Moore N (2007) Channelling of COX-2 inhibitors to patients at higher gastrointestinal risk but not at lower cardiovascular risk: the Cox2 inhibitors and tNSAIDs description of users (CADEUS) study. Pharmacoepidemiol Drug Saf 16(8):891-900 (Pubitemid 47322589)
4. Vane JR (1971) Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 231(25):232-235
5. Silverstein FE, Faich G, Goldstein JL, Simon LS, Pincus T, Whelton A, Makuch R, Eisen G, Agrawal NM, Stenson WF, Burr AM, Zhao WW, Kent JD, Lefkowith JB, Verburg KM, Geis GS (2000) Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Longterm Arthritis Safety Study. JAMA 284(10):1247-1255
6. Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg MC, Kvien TK, Schnitzer TJ (2000) Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 343 (21):1520-1528
7. Hermann M (2009) Cardiovascular risk associated with nonsteroidal anti-inflammatory drugs. Curr Rheumatol Rep 11(1):31-35
8. Beers MH (1997) Explicit criteria for determining potentially inappropriate medication use by the elderly. An update. Arch Intern Med 157(14):1531-1536
9. Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC (1991) Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med 151(9):1825-1832
10. Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH (2003) Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 163(22):2716-2724 (Pubitemid 37517412)
11. Afssaps (2006) Rappel des règles de bon usage des AINS. Afssaps, France
12. Afssaps (2006) Evaluation des nouvelles données de tolérance cardiovasculaire : Le rapport bénéfice/risque des AINS reste favorable mais les précautions d'emploi doivent être renforcées. In: Afssaps, France
13. Moore N (2003) Place of OTC analgesics and NSAIDs in osteoarthritis. Inflammopharmacology 11(4):355-362
14. Moore N, Verschuren X, Montout C, Callens J, Kong SX, Begaud B (2000) Excess costs related to non-steroidal anti-inflammatory drug utilization in general practice. Therapie 55(1):133-136 (Pubitemid 30319271)
15. Becker JC, Domschke W, Pohle T (2004) Current approaches to prevent NSAID-induced gastropathy - COX selectivity and beyond. Br J Clin Pharmacol 58(6):587-600 (Pubitemid 39665146)
16. Gallagher PF, Barry PJ, Ryan C, Hartigan I, O"Mahony D (2008) Inappropriate prescribing in an acutely ill population of elderly patients as determined by Beers" Criteria. Age Ageing 37(1):96-101
17. O"Mahony D, Gallagher PF (2008) Inappropriate prescribing in the older population: need for new criteria. Age Ageing 37(2):138-141