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Volumn 65, Issue 10, 2011, Pages 1015-1023

The contribution of low-affinity transport mechanisms to serotonin clearance in synaptosomes

Author keywords

D 22; Decynium 22; Knockout; Serotonin; SERT; Transporter; Uptake; Voltammetry

Indexed keywords

SEROTONIN; SEROTONIN TRANSPORTER;

EID: 79960950288     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20929     Document Type: Article
Times cited : (23)

References (41)
  • 1
    • 78149477451 scopus 로고    scopus 로고
    • Repeated swim impairs serotonin clearance via a corticosterone-sensitive mechanism: Organic cation transporter 3, the smoking gun
    • Baganz N, Horton R, Martin K, Holmes A, Daws LC. 2010. Repeated swim impairs serotonin clearance via a corticosterone-sensitive mechanism: Organic cation transporter 3, the smoking gun. J Neurosci 30: 15185-15195.
    • (2010) J Neurosci , vol.30 , pp. 15185-15195
    • Baganz, N.1    Horton, R.2    Martin, K.3    Holmes, A.4    Daws, L.C.5
  • 3
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice
    • Bengel D, Murphy DL, Andrews AM, Wichems CH, Feltner D, Heils A, Mossner R, Westphal H, Lesch KP. 1998. Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice. Mol Pharmacol 53: 649-655.
    • (1998) Mol Pharmacol , vol.53 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3    Wichems, C.H.4    Feltner, D.5    Heils, A.6    Mossner, R.7    Westphal, H.8    Lesch, K.P.9
  • 4
    • 0014115406 scopus 로고
    • 5-Hydroxytryptamine uptake by rat brain in vitro
    • Blackburn KJ, French PC, Merrills RJ. 1967. 5-Hydroxytryptamine uptake by rat brain in vitro. Life Sci 6: 1653-1663.
    • (1967) Life Sci , vol.6 , pp. 1653-1663
    • Blackburn, K.J.1    French, P.C.2    Merrills, R.J.3
  • 6
    • 0032125492 scopus 로고    scopus 로고
    • Quantitative evaluation of 5-hydroxytryptamine (serotonin) neuronal release and uptake: An investigation of extrasynaptic transmission
    • Bunin MA, Wightman RM. 1998. Quantitative evaluation of 5-hydroxytryptamine (serotonin) neuronal release and uptake: An investigation of extrasynaptic transmission. J Neurosci 18: 4854-4860.
    • (1998) J Neurosci , vol.18 , pp. 4854-4860
    • Bunin, M.A.1    Wightman, R.M.2
  • 7
    • 0033198725 scopus 로고    scopus 로고
    • Paracrine neurotransmission in the CNS: Involvement of 5-HT
    • Bunin MA, Wightman RM. 1999. Paracrine neurotransmission in the CNS: Involvement of 5-HT. Trends Neurosci 22: 377-382.
    • (1999) Trends Neurosci , vol.22 , pp. 377-382
    • Bunin, M.A.1    Wightman, R.M.2
  • 8
    • 0035882382 scopus 로고    scopus 로고
    • Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters
    • Chen JJ, Li Z, Pan H, Murphy DL, Tamir H, Koepsell H, Gershon MD. 2001. Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters. J Neurosci 21: 6348-6361.
    • (2001) J Neurosci , vol.21 , pp. 6348-6361
    • Chen, J.J.1    Li, Z.2    Pan, H.3    Murphy, D.L.4    Tamir, H.5    Koepsell, H.6    Gershon, M.D.7
  • 9
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
    • Cheng Y, Prusoff WH. 1973. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol 22: 3099-3108.
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 11
    • 57749097458 scopus 로고    scopus 로고
    • Unfaithful neurotransmitter transporters: Focus on serotonin uptake and implications for antidepressant efficacy
    • Daws LC. 2009. Unfaithful neurotransmitter transporters: Focus on serotonin uptake and implications for antidepressant efficacy. Pharmacol Ther 121: 89-99.
    • (2009) Pharmacol Ther , vol.121 , pp. 89-99
    • Daws, L.C.1
  • 14
    • 85057707864 scopus 로고    scopus 로고
    • High-speed chronoamperometry to study kinetics and mechanisms for serotonin clearance in vivo
    • In: Michael AC,Borland LM, editors. Boca Raton, FL: CRC Press.
    • Daws LC, Toney GM. 2007. High-speed chronoamperometry to study kinetics and mechanisms for serotonin clearance in vivo. In: Michael AC, Borland LM, editors. Electrochemical methods for neuroscience. Boca Raton, FL: CRC Press. p 63-81.
    • (2007) Electrochemical methods for neuroscience , pp. 63-81
    • Daws, L.C.1    Toney, G.M.2
  • 15
    • 27544453846 scopus 로고    scopus 로고
    • Interaction of organic cations with a newly identified plasma membrane monoamine transporter
    • Engel K, Wang J. 2005. Interaction of organic cations with a newly identified plasma membrane monoamine transporter. Mol Pharmacol 68: 1397-1407.
    • (2005) Mol Pharmacol , vol.68 , pp. 1397-1407
    • Engel, K.1    Wang, J.2
  • 16
    • 77950033374 scopus 로고    scopus 로고
    • Organic cation transporter inhibition increases medial hypothalamic serotonin under basal conditions and during mild restraint
    • Feng N, Lowry CA, Lukkes JL, Orchinik M, Forster GL, Renner KJ. 2010. Organic cation transporter inhibition increases medial hypothalamic serotonin under basal conditions and during mild restraint. Brain Res 1326: 105-113.
    • (2010) Brain Res , vol.1326 , pp. 105-113
    • Feng, N.1    Lowry, C.A.2    Lukkes, J.L.3    Orchinik, M.4    Forster, G.L.5    Renner, K.J.6
  • 17
    • 27744531970 scopus 로고    scopus 로고
    • Local inhibition of organic cation transporters increases extracellular serotonin in the medial hypothalamus
    • Feng N, Mo B, Johnson PL, Orchinik M, Lowry CA, Renner KJ. 2005. Local inhibition of organic cation transporters increases extracellular serotonin in the medial hypothalamus. Brain Res 1063: 69-76.
    • (2005) Brain Res , vol.1063 , pp. 69-76
    • Feng, N.1    Mo, B.2    Johnson, P.L.3    Orchinik, M.4    Lowry, C.A.5    Renner, K.J.6
  • 18
    • 0027474725 scopus 로고
    • Rapid and simultaneous determination of monoamine oxidase A and monoamine oxidase B activities in mouse brain homogenates by liquid chromatography with electrochemical detection
    • Freeman KB, Bulawa MC, Zeng Q, Blank CL. 1993. Rapid and simultaneous determination of monoamine oxidase A and monoamine oxidase B activities in mouse brain homogenates by liquid chromatography with electrochemical detection. Anal Biochem 208: 182-196.
    • (1993) Anal Biochem , vol.208 , pp. 182-196
    • Freeman, K.B.1    Bulawa, M.C.2    Zeng, Q.3    Blank, C.L.4
  • 20
    • 33748264554 scopus 로고    scopus 로고
    • Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: Potential role for organic cation transporter 3 in stress-induced modulation of monoaminergic neurotransmission
    • Gasser PJ, Lowry CA, Orchinik M. 2006. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: Potential role for organic cation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci 26: 8758-8766.
    • (2006) J Neurosci , vol.26 , pp. 8758-8766
    • Gasser, P.J.1    Lowry, C.A.2    Orchinik, M.3
  • 21
    • 59649089875 scopus 로고    scopus 로고
    • Distribution of organic cation transporter 3, a corticosterone-sensitive monoamine transporter, in the rat brain
    • Gasser PJ, Orchinik M, Raju I, Lowry CA. 2009. Distribution of organic cation transporter 3, a corticosterone-sensitive monoamine transporter, in the rat brain. J Comp Neurol 512: 529-555.
    • (2009) J Comp Neurol , vol.512 , pp. 529-555
    • Gasser, P.J.1    Orchinik, M.2    Raju, I.3    Lowry, C.A.4
  • 22
    • 77957652856 scopus 로고    scopus 로고
    • Rotating disk electrode voltammetric measurements of serotonin transporter kinetics in synaptosomes
    • Hagan CE, Neumaier JF, Schenk JO. 2010. Rotating disk electrode voltammetric measurements of serotonin transporter kinetics in synaptosomes. J Neurosci Methods 193: 29-38.
    • (2010) J Neurosci Methods , vol.193 , pp. 29-38
    • Hagan, C.E.1    Neumaier, J.F.2    Schenk, J.O.3
  • 23
    • 0001576506 scopus 로고    scopus 로고
    • Liquid chromatographic determination of serotonin in homogenized dog intestine and rat brain tissue using a 2 mm i.d. PEEK column
    • Huang T, Kissinger PT. 1996. Liquid chromatographic determination of serotonin in homogenized dog intestine and rat brain tissue using a 2 mm i.d. PEEK column. Curr Sep 14: 114-119.
    • (1996) Curr Sep , vol.14 , pp. 114-119
    • Huang, T.1    Kissinger, P.T.2
  • 24
    • 0037269107 scopus 로고    scopus 로고
    • Expression and functional characterization of the extraneuronal monoamine transporter in normal human astrocytes
    • Inazu M, Takeda H, Matsumiya T. 2003. Expression and functional characterization of the extraneuronal monoamine transporter in normal human astrocytes. J Neurochem 84: 43-52.
    • (2003) J Neurochem , vol.84 , pp. 43-52
    • Inazu, M.1    Takeda, H.2    Matsumiya, T.3
  • 25
    • 0030845499 scopus 로고    scopus 로고
    • The effects of different stressors on extracellular 5-hydroxytryptamine and 5-hydroxyindoleacetic acid
    • Kirby LG, Chou-Green JM, Davis K, Lucki I. 1997. The effects of different stressors on extracellular 5-hydroxytryptamine and 5-hydroxyindoleacetic acid. Brain Res 760: 218-230.
    • (1997) Brain Res , vol.760 , pp. 218-230
    • Kirby, L.G.1    Chou-Green, J.M.2    Davis, K.3    Lucki, I.4
  • 26
    • 0038002954 scopus 로고    scopus 로고
    • Uptake of serotonin at the apical and basolateral membranes of human intestinal epithelial (Caco-2) cells occurs through the neuronal serotonin transporter (SERT)
    • Martel F, Monteiro R, Lemos C. 2003. Uptake of serotonin at the apical and basolateral membranes of human intestinal epithelial (Caco-2) cells occurs through the neuronal serotonin transporter (SERT). J Pharmacol Exp Ther 306: 355-362.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 355-362
    • Martel, F.1    Monteiro, R.2    Lemos, C.3
  • 27
    • 10344221595 scopus 로고    scopus 로고
    • Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression
    • Mathews TA, Fedele DE, Coppelli FM, Avila AM, Murphy DL, Andrews AM. 2004. Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. J Neurosci Methods 140: 169-181.
    • (2004) J Neurosci Methods , vol.140 , pp. 169-181
    • Mathews, T.A.1    Fedele, D.E.2    Coppelli, F.M.3    Avila, A.M.4    Murphy, D.L.5    Andrews, A.M.6
  • 28
    • 33645452696 scopus 로고    scopus 로고
    • Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
    • Millan MJ. 2006. Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application. Pharmacol Ther 110: 135-370.
    • (2006) Pharmacol Ther , vol.110 , pp. 135-370
    • Millan, M.J.1
  • 29
    • 0037111154 scopus 로고    scopus 로고
    • Differential in vivo clearance of serotonin in rat dorsal raphe nucleus and CA3 region
    • Montanez S, Daws LC, Gould GG, Gerhardt GA, Frazer A. 2002. Differential in vivo clearance of serotonin in rat dorsal raphe nucleus and CA3 region. Brain Res 955: 236-244
    • (2002) Brain Res , vol.955 , pp. 236-244
    • Montanez, S.1    Daws, L.C.2    Gould, G.G.3    Gerhardt, G.A.4    Frazer, A.5
  • 31
    • 0035977577 scopus 로고    scopus 로고
    • Plasticity in serotonin uptake in primary neuronal cultures of serotonin transporter knockout mice
    • Pan Y, Gembom E, Peng W, Lesch KP, Mossner R, Simantov R. 2001. Plasticity in serotonin uptake in primary neuronal cultures of serotonin transporter knockout mice. Brain Res Dev Brain Res 126: 125-129.
    • (2001) Brain Res Dev Brain Res , vol.126 , pp. 125-129
    • Pan, Y.1    Gembom, E.2    Peng, W.3    Lesch, K.P.4    Mossner, R.5    Simantov, R.6
  • 32
    • 0027365495 scopus 로고
    • Cyanine-related compounds: A novel class of potent inhibitors of extraneuronal noradrenaline transport
    • Russ H, Sonna K, Keppler S, Baunach S, Schomig E. 1993. Cyanine-related compounds: A novel class of potent inhibitors of extraneuronal noradrenaline transport. Naunyn Schmiedebergs Arch Pharmacol 348: 458-465.
    • (1993) Naunyn Schmiedebergs Arch Pharmacol , vol.348 , pp. 458-465
    • Russ, H.1    Sonna, K.2    Keppler, S.3    Baunach, S.4    Schomig, E.5
  • 33
    • 0030009888 scopus 로고    scopus 로고
    • The extraneuronal transporter for monoamine transmitters exists in cells derived from human central nervous system glia
    • Russ H, Staust K, Martel F, Gliese M, Schomig E. 1996. The extraneuronal transporter for monoamine transmitters exists in cells derived from human central nervous system glia. Eur J Neurosci 8: 1256-1264.
    • (1996) Eur J Neurosci , vol.8 , pp. 1256-1264
    • Russ, H.1    Staust, K.2    Martel, F.3    Gliese, M.4    Schomig, E.5
  • 34
    • 2442453534 scopus 로고    scopus 로고
    • Toward a rapidly acting antidepressant: The normetanephrine and extraneuronal monoamine transporter (uptake 2) hypothesis
    • Schildkraut JJ, Mooney JJ. 2004. Toward a rapidly acting antidepressant: The normetanephrine and extraneuronal monoamine transporter (uptake 2) hypothesis. Am J Psychiatry 161: 909-911.
    • (2004) Am J Psychiatry , vol.161 , pp. 909-911
    • Schildkraut, J.J.1    Mooney, J.J.2
  • 36
    • 0344406174 scopus 로고    scopus 로고
    • 1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3
    • Shang T, Uihlein AV, van Asten J, Kalyanaraman B, Hillard CJ. 2003. 1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3. J Neurochem 85: 358-367.
    • (2003) J Neurochem , vol.85 , pp. 358-367
    • Shang, T.1    Uihlein, A.V.2    van Asten, J.3    Kalyanaraman, B.4    Hillard, C.J.5
  • 39
    • 75149130839 scopus 로고    scopus 로고
    • Corticotropin-releasing factor in the dorsal raphe nucleus: Linking stress coping and addiction
    • Valentino RJ, Lucki I, van Bockstaele E. 2010. Corticotropin-releasing factor in the dorsal raphe nucleus: Linking stress coping and addiction. Brain Res 1314: 29-37.
    • (2010) Brain Res , vol.1314 , pp. 29-37
    • Valentino, R.J.1    Lucki, I.2    van Bockstaele, E.3
  • 41
    • 66449091213 scopus 로고    scopus 로고
    • Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity
    • Xia L, Zhou M, Kalhorn TF, Ho HT, Wang J. 2009. Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity. Am J Physiol Renal Physiol 296: F1307-F1313.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Xia, L.1    Zhou, M.2    Kalhorn, T.F.3    Ho, H.T.4    Wang, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.