Accuracy of five algorithms to diagnose gambiense human african trypanosomiasis

PLoS Neglected Tropical Diseases

Volumn 5, Issue 7, 2011, Pages

  Checchi, Francesco ^a   Chappuis, François ^b,c   Karunakara, Unni ^b,d   Priotto, Gerardo ^e   Chandramohan, Daniel ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b MÉDECINS SANS FRONTIÈRES   (Switzerland)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^d Columbia University ^*  (United States)

^e EPICENTRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICAN TRYPANOSOMIASIS; ARTICLE; CLASSIFICATION ALGORITHM; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE CLASSIFICATION; DISEASE SEVERITY; MATHEMATICAL MODEL; PREDICTIVE VALUE; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS; ALGORITHM; CONGO; DIAGNOSTIC PROCEDURE; EVALUATION; HUMAN; IMMUNOASSAY; IMMUNOLOGY; ISOLATION AND PURIFICATION; METHODOLOGY; PARASITOLOGY; PATHOLOGY; SUDAN; TRYPANOSOMA; UGANDA;

ALGORITHMS; CONGO; DIAGNOSTIC TECHNIQUES AND PROCEDURES; HUMANS; IMMUNOASSAY; PARASITOLOGY; SENSITIVITY AND SPECIFICITY; SUDAN; TRYPANOSOMA BRUCEI GAMBIENSE; TRYPANOSOMIASIS, AFRICAN; UGANDA;

EID: 79960937642     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001233     Document Type: Article

References (66)

1. Chappuis F, Loutan L, Simarro P, Lejon V, Buscher P, (2005) Options for field diagnosis of human african trypanosomiasis. Clin Microbiol Rev 18: 133-146.
2. Barrett MP, Boykin DW, Brun R, Tidwell RR, (2007) Human African trypanosomiasis: pharmacological re-engagement with a neglected disease. Br J Pharmacol 152: 1155-1171.
3. Blum J, Nkunku S, Burri C, (2001) Clinical description of encephalopathic syndromes and risk factors for their occurrence and outcome during melarsoprol treatment of human African trypanosomiasis. Trop Med Int Health 6: 390-400.
4. Magnus E, Vervoort T, Van Meirvenne N, (1978) A card-agglutination test with stained trypanosomes (C.A.T.T.) for the serological diagnosis of T. B. gambiense trypanosomiasis. Ann Soc Belg Med Trop 58: 169-176.
5. Lejon V, Buscher P, (2005) Review Article: cerebrospinal fluid in human African trypanosomiasis: a key to diagnosis, therapeutic decision and post-treatment follow-up. Trop Med Int Health 10: 395-403.
6. Chappuis F, Stivanello E, Adams K, Kidane S, Pittet A, et al. (2004) Card agglutination test for trypanosomiasis (CATT) end-dilution titer and cerebrospinal fluid cell count as predictors of human African Trypanosomiasis (Trypanosoma brucei gambiense) among serologically suspected individuals in southern Sudan. Am J Trop Med Hyg 71: 313-317.
7. Garcia A, Jamonneau V, Magnus E, Laveissiere C, Lejon V, et al. (2000) Follow-up of Card Agglutination Trypanosomiasis Test (CATT) positive but apparently aparasitaemic individuals in Cote d'Ivoire: evidence for a complex and heterogeneous population. Trop Med Int Health 5: 786-793.
8. Simarro PP, Ruiz JA, Franco JR, Josenando T, (1999) Attitude towards CATT-positive individuals without parasitological confirmation in the African Trypanosomiasis (T.b. gambiense) focus of Quicama (Angola). Trop Med Int Health 4: 858-861.
9. World Health Organization (1998) Control and surveillance of African trypanosomiasis Geneva WHO.
10. Woo PT, (1970) The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis. Acta Trop 27: 384-386.
11. Bailey JW, Smith DH, (1994) The quantitative buffy coat for the diagnosis of trypanosomes. Trop Doct 24: 54-56.
12. Lumsden WH, Kimber CD, Evans DA, Doig SJ, (1979) Trypanosoma brucei: Miniature anion-exchange centrifugation technique for detection of low parasitaemias: Adaptation for field use. Trans R Soc Trop Med Hyg 73: 312-317.
13. Balasegaram M, Harris S, Checchi F, Hamel C, Karunakara U, (2006) Treatment outcomes and risk factors for relapse in patients with early-stage human African trypanosomiasis (HAT) in the Republic of the Congo. Bull World Health Organ 84: 777-782.
14. World Health Organization (2007) Recommendations of the informal consultation on issues for clinical product development for human African trypanosomiasis Geneva World Health Organization WHO/CDS/NTD/IDM/2007.1 WHO/CDS/NTD/IDM/2007.1.
15. Lejon V, Boelaert M, Jannin J, Moore A, Buscher P, (2003) The challenge of Trypanosoma brucei gambiense sleeping sickness diagnosis outside Africa. Lancet Infect Dis 3: 804-808.
16. Lejon V, Reiber H, Legros D, Dje N, Magnus E, et al. (2003) Intrathecal immune response pattern for improved diagnosis of central nervous system involvement in trypanosomiasis. J Infect Dis 187: 1475-1483.
17. Noireau F, Gouteux JP, Duteurtre JP, (1987) [Diagnostic value of a card agglutination test (Testryp CATT) in the mass screening of human trypanosomiasis in the Congo]. Bull Soc Pathol Exot Filiales 80: 797-803.
18. Duvallet G, Saccharin C, Vivant JF, Stanghellini A, (1979) [African human trypanosomiasis: diagnosis by haematocrit centrifuge technique (author's transl)]. Nouv Presse Med 8: 214-215.
19. Henry MC, Kageruka P, Ruppol JF, Bruneel H, Claes Y, (1981) [Evaluation of field diagnosis of trypanosomiasis caused by Trypanosoma brucei gambiense]. Ann Soc Belg Med Trop 61: 79-92.
20. Truc P, Jamonneau V, N'Guessan P, Diallo PB, Garcia A, (1998) Parasitological diagnosis of human African trypanosomiasis: a comparison of the OBC and miniature anion-exchange centrifugation techniques. Trans R Soc Trop Med Hyg 92: 288-289.
21. Simarro PP, Franco JR, Ndongo P, (1999) Field evaluation of several serologic screening tests for sleeping sickness (T.b. gambiense). Bulletin De Liaison et Documentation de l'Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale 32: 28-33.
22. Inojosa WO, Augusto I, Bisoffi Z, Josenado T, Abel PM, et al. (2006) Diagnosing human African trypanosomiasis in Angola using a card agglutination test: observational study of active and passive case finding strategies. Bmj 332: 1479.
23. Pepin J, Guern C, Mercier D, Moore P, (1986) [Use of the CATT Testryp in screening for trypanosomiasis in Nioki, Zaire]. Ann Soc Belg Med Trop 66: 213-224.
24. Ancelle T, Paugam A, Bourlioux F, Merad A, Vigier JP, (1997) [Detection of trypanosomes in blood by the Quantitative Buffy Coat (QBC) technique: experimental evaluation]. Med Trop (Mars) 57: 245-248.
25. Cattand P, Miezan BT, de Raadt P, (1988) Human African trypanosomiasis: use of double centrifugation of cerebrospinal fluid to detect trypanosomes. Bull World Health Organ 66: 83-86.
26. Courtioux B, Bisser S, M'Belesso P, Ngoungou E, Girard M, et al. (2005) Dot enzyme-linked immunosorbent assay for more reliable staging of patients with Human African trypanosomiasis. J Clin Microbiol 43: 4789-4795.
27. Jamonneau V, Solano P, Cuny G, (2001) [Use of molecular biology in the diagnosis of human African trypanosomiasis]. Med Trop (Mars) 61: 347-354.
28. Becker S, Franco JR, Simarro PP, Stich A, Abel PM, et al. (2004) Real-time PCR for detection of Trypanosoma brucei in human blood samples. Diagn Microbiol Infect Dis 50: 193-199.
29. Koffi M, Solano P, Denizot M, Courtin D, Garcia A, et al. (2006) Aparasitemic serological suspects in Trypanosoma brucei gambiense human African trypanosomiasis: a potential human reservoir of parasites? Acta Trop 98: 183-188.
30. Penchenier L, Simo G, Grebaut P, Nkinin S, Laveissiere C, et al. (2000) Diagnosis of human trypanosomiasis, due to Trypanosoma brucei gambiense in central Africa, by the polymerase chain reaction. Trans R Soc Trop Med Hyg 94: 392-394.
31. Radwanska M, Claes F, Magez S, Magnus E, Perez-Morga D, et al. (2002) Novel primer sequences for polymerase chain reaction-based detection of Trypanosoma brucei gambiense. Am J Trop Med Hyg 67: 289-295.
32. Kabiri M, Franco JR, Simarro PP, Ruiz JA, Sarsa M, et al. (1999) Detection of Trypanosoma brucei gambiense in sleeping sickness suspects by PCR amplification of expression-site-associated genes 6 and 7. Trop Med Int Health 4: 658-661.
33. Checchi F, Filipe JA, Haydon DT, Chandramohan D, Chappuis F, (2008) Estimates of the duration of the early and late stage of gambiense sleeping sickness. BMC Infect Dis 8: 16.
34. Miezan TW, Meda AH, Doua F, Cattand P, (1994) [Evaluation of the parasitologic technics used in the diagnosis of human Trypanosoma gambiense trypanosomiasis in the Ivory Coast]. Bull Soc Pathol Exot 87: 101-104.
35. Robays J, Bilengue MM, Van der Stuyft P, Boelaert M, (2004) The effectiveness of active population screening and treatment for sleeping sickness control in the Democratic Republic of Congo. Trop Med Int Health 9: 542-550.
36. Lutumba P, Meheus F, Robays J, Miaka C, Kande V, et al. (2007) Cost-effectiveness of Algorithms for Confirmation Test of Human African Trypanosomiasis. Emerg Infect Dis 13: 1484-1490.
37. Checchi F, Filipe JA, Barrett MP, Chandramohan D, (2008) The natural progression of Gambiense sleeping sickness: what is the evidence? PLoS Negl Trop Dis 2: e303.
38. Cox A, Tilley A, McOdimba F, Fyfe J, Eisler M, et al. (2005) A PCR based assay for detection and differentiation of African trypanosome species in blood. Exp Parasitol 111: 24-29.
39. Deeks JJ, (2001) Systematic reviews in health care: Systematic reviews of evaluations of diagnostic and screening tests. Bmj 323: 157-162.
40. Deville WL, Buntinx F, Bouter LM, Montori VM, de Vet HC, et al. (2002) Conducting systematic reviews of diagnostic studies: didactic guidelines. BMC Med Res Methodol 2: 9.
41. de Clare Bronsvoort BM, von Wissmann B, Fevre EM, Handel IG, Picozzi K, et al. (2010) No gold standard estimation of the sensitivity and specificity of two molecular diagnostic protocols for Trypanosoma brucei spp. in Western Kenya. PLoS One 5: e8628.
42. Enoe C, Georgiadis MP, Johnson WO, (2000) Estimation of sensitivity and specificity of diagnostic tests and disease prevalence when the true disease state is unknown. Prev Vet Med 45: 61-81.
43. Brun R, Balmer O, (2006) New developments in human African trypanosomiasis. Curr Opin Infect Dis 19: 415-420.
44. Campaign for Access to Essential Medicines (2006) Human African Trypanosomiasis- Facing the challenges caused by neglect: the need for new treatment and diagnostics Geneva Medecins Sans Frontieres.
45. Magnus E, Lejon V, Bayon D, Buyse D, Simarro P, et al. (2002) Evaluation of an EDTA version of CATT/Trypanosoma brucei gambiense for serological screening of human blood samples. Acta Trop 81: 7-12.
46. Truc P, Lejon V, Magnus E, Jamonneau V, Nangouma A, et al. (2002) Evaluation of the micro-CATT, CATT/Trypanosoma brucei gambiense, and LATEX/T b gambiense methods for serodiagnosis and surveillance of human African trypanosomiasis in West and Central Africa. Bull World Health Organ 80: 882-886.
47. Noireau F, Lemesre JL, Nzoukoudi MY, Louembet MT, Gouteux JP, et al. (1988) Serodiagnosis of sleeping sickness in the Republic of the Congo: comparison of indirect immunofluorescent antibody test and card agglutination test. Trans R Soc Trop Med Hyg 82: 237-240.
48. Penchenier L, Grebaut P, Njokou F, Eboo Eyenga V, Buscher P, (2003) Evaluation of LATEX/T.b.gambiense for mass screening of Trypanosoma brucei gambiense sleeping sickness in Central Africa. Acta Trop 85: 31-37.
49. Jamonneau V, Truc P, Garcia A, Magnus E, Buscher P, (2000) Preliminary evaluation of LATEX/T. b. gambiense and alternative versions of CATT/T. b. gambiense for the serodiagnosis of human african trypanosomiasis of a population at risk in Cote d'Ivoire: considerations for mass-screening. Acta Trop 76: 175-183.
50. Enyaru JC, Matovu E, Akol M, Sebikali C, Kyambadde J, et al. (1998) Parasitological detection of Trypanosoma brucei gambiense in serologically negative sleeping-sickness suspects from north-western Uganda. Ann Trop Med Parasitol 92: 845-850.
51. Gastellu Etchegorry M, Godin C, Fievet N, Aquadro B, (1987) Study about the specificity and sensitivity of the CATT. Medecins Sans Frontieres.
52. Miezan T, Doua F, Cattand P, de Raadt P, (1991) [Evaluation of Testryp CATT applied to blood samples on filter paper and on diluted blood in a focus of trypanosomiasis due to Trypanosoma brucei gambiense in the Ivory Coast]. Bull World Health Organ 69: 603-606.
53. Bafort JM, Schutte CH, Gathiram V, (1986) Specificity of the Testryp CATT card agglutination test in a non-sleeping-sickness area of Africa. S Afr Med J 69: 541-542.
54. Paquet C, (1992) Depistage de la trypanosomiase en Ouganda: strategie d'utilisation du test d'agglutination sur carte (CATT T.b. gambiense). Bordeaux: Universite de Bordeaux II.
55. Lutumba P, Robays J, Miaka C, Kande V, Mumba D, et al. (2006) [Validity, cost and feasibility of the mAECT and CTC confirmation tests after diagnosis of African of sleeping sickness]. Trop Med Int Health 11: 470-478.
56. Magnus E, Vervoort T, Van Meirvenne N, (1991) Laboratory evaluation of the card agglutination test (CATT) for serodiagnosis of sleeping sickness due to T.b. gambiense. Institute of Tropical Medicine, Antwerp, Belgium.
57. Bailey JW, Smith DH, (1992) The use of the acridine orange QBC technique in the diagnosis of African trypanosomiasis. Trans R Soc Trop Med Hyg 86: 630.
58. Truc P, Bailey JW, Doua F, Laveissiere C, Godfrey DG, (1994) A comparison of parasitological methods for the diagnosis of gambian trypanosomiasis in an area of low endemicity in Cote d'Ivoire. Trans R Soc Trop Med Hyg 88: 419-421.
59. Lumsden WH, Kimber CD, Dukes P, Haller L, Stanghellini A, et al. (1981) Field diagnosis of sleeping sickness in the Ivory Coast. I. Comparison of the miniature anion-exchange/centrifugation technique with other protozoological methods. Trans R Soc Trop Med Hyg 75: 242-250.
60. Kyambadde JW, Enyaru JC, Matovu E, Odiit M, Carasco JF, (2000) Detection of trypanosomes in suspected sleeping sickness patients in Uganda using the polymerase chain reaction. Bull World Health Organ 78: 119-124.
61. Miezan TW, Meda HA, Doua F, Yapo FB, Baltz T, (1998) Assessment of central nervous system involvement in gambiense trypanosomiasis: value of the cerebro-spinal white cell count. Trop Med Int Health 3: 571-575.
62. Jamonneau V, Solano P, Garcia A, Lejon V, Dje N, et al. (2003) Stage determination and therapeutic decision in human African trypanosomiasis: value of polymerase chain reaction and immunoglobulin M quantification on the cerebrospinal fluid of sleeping sickness patients in Cote d'Ivoire. Trop Med Int Health 8: 589-594.
63. Bisser S, Lejon V, Preux PM, Bouteille B, Stanghellini A, et al. (2002) Blood-cerebrospinal fluid barrier and intrathecal immunoglobulins compared to field diagnosis of central nervous system involvement in sleeping sickness. J Neurol Sci 193: 127-135.
64. Burri C, Brun R, (2003) Human African trypanosomiasis. In: Cook GC, Zumla A, editors. Manson's tropical diseases. 21 ed London Elsevier Science limited pp. 1303-1323.
65. Molisho S, Place des techniques serologiques et parasitologiques dans le depistage de la Trypanosomiase Humaine Africaine a Trypanosoma brucei gambiense par les equipes mobiles au Zaïre. In: Habbema JDF, De Muynck A, editors. 1991; Daloa, Cote d'Ivoire Erasmus University pp. 67-72.
66. Programme National de Lutte contre la Trypanosomiase Humaine Africaine (2003) Rapport annuel des activités THA en Equateur Nord Kinshasa Ministry of Health.