Toluene exposure during brain growth spurt and adolescence produces differential effects on N-methyl-d-aspartate receptor-mediated currents in rat hippocampus

Toxicology Letters

Volumn 205, Issue 3, 2011, Pages 336-340

  Chen, Hwei Hsien ^a   Lin, Yi Ruu ^a   Chan, Ming Huan ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Adolescent; EPSCs; Neonatal; NMDA receptor; Solvent

Indexed keywords

2 AMINO 6 PHOSPHONOPENTANOIC ACID; CORN OIL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; TOLUENE; UNCLASSIFIED DRUG;

ADOLESCENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN GROWTH; BRAIN SLICE; CONTROLLED STUDY; ELECTROSTIMULATION; ENVIRONMENTAL EXPOSURE; EVOKED RESPONSE; EXCITATORY POSTSYNAPTIC POTENTIAL; FACILITATION; FEMALE; GROWTH ACCELERATION; HIPPOCAMPUS; NERVE CELL DIFFERENTIATION; NERVE CELL MEMBRANE POTENTIAL; NEUROTOXICITY; NONHUMAN; PAIRED PULSE FACILITATION; PERINATAL PERIOD; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

AGING; ANIMALS; CA1 REGION, HIPPOCAMPAL; ELECTRIC STIMULATION; EXCITATORY AMINO ACID AGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; INHALANT ABUSE; INJECTIONS, INTRAPERITONEAL; MALE; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; NEURAL CONDUCTION; NEURONS; NEUROTOXICITY SYNDROMES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SOLVENTS; TOLUENE;

RATTUS; ZEA MAYS;

EID: 79960913475     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.06.026     Document Type: Article

References (29)

1. Bausch S.B., He S., Dong Y. Inverse relationship between seizure expression and extrasynaptic NMDAR function following chronic NMDAR inhibition. Epilepsia 2010, 51(Suppl. 3):102-105.
2. Bonci A., Williams J.T. Increased probability of GABA release during withdrawal from morphine. J. Neurosci. 1997, 17:796-803.
3. Chan M.H., Chien T.H., Lee P.Y., Chen H.H. Involvement of NO/cGMP pathway in toluene-induced locomotor hyperactivity in female rats. Psychopharmacology (Berl.) 2004, 176:435-439.
4. Chen H.H., Lee Y.F. Neonatal toluene exposure selectively alters sensitivity to different chemoconvulsant drugs in juvenile rats. Pharmacol. Biochem. Behav. 2002, 73:921-927.
5. Chen H.H., Wei C.T., Lin Y.R., Chien T.H., Chan M.H. Neonatal toluene exposure alters agonist and antagonist sensitivity and NR2B subunit expression of NMDA receptors in cultured cerebellar granule neurons. Toxicol. Sci. 2005, 85:666-674.
6. Chien T.H., Chan M.H., Tang Y.C., Chen H.H. Toluene exposure during the brain growth spurt reduces behavioral responses to noncompetitive N-methyl-d-aspartate receptor antagonists in adult rats. Psychopharmacology (Berl.) 2005, 182:468-474.
7. Contestabile A. Roles of NMDA receptor activity and nitric oxide production in brain development. Brain Res. Brain Res. Rev. 2000, 32:476-509.
8. Cruz S.L., Mirshahi T., Thomas B., Balster R.L., Woodward J.J. Effects of the abused solvent toluene on recombinant N-methyl-d-aspartate and non-N-methyl-d-aspartate receptors expressed in Xenopus oocytes. J. Pharmacol. Exp. Ther. 1998, 286:334-340.
9. Cull-Candy S., Brickley S., Farrant M. NMDA receptor subunits: diversity, development and disease. Curr. Opin. Neurobiol. 2001, 11:327-335.
10. Cull-Candy S.G., Leszkiewicz D.N. Role of distinct NMDA receptor subtypes at central synapses. Sci. STKE 2004, 2004:re16.
11. Dobbing J., Sands J. Comparative aspects of the brain growth spurt. Early Hum. Dev. 1979, 3:79-83.
12. Dobrunz L.E., Stevens C.F. Response of hippocampal synapses to natural stimulation patterns. Neuron 1999, 22:157-166.
13. Garriott J.C., Foerster E., Juarez L., de la Garza F., Mendiola I., Curoe J. Measurement of toluene in blood and breath in cases of solvent abuse. Clin. Toxicol. 1981, 18:471-479.
14. Gordon C.J., Gottipolu R.R., Kenyon E.M., Thomas R., Schladweiler M.C., Mack C.M., Shannahan J.H., Wallenborn J.G., Nyska A., MacPhail R.C., Richards J.E., Devito M., Kodavanti U.P. Aging and susceptibility to toluene in rats: a pharmacokinetic, biomarker, and physiological approach. J. Toxicol. Environ. Health A 2010, 73:301-318.
15. Lee Y.F., Lo P.S., Wang Y.J., Hu A., Chen H.H. Neonatal toluene exposure alters N-methyl-d-aspartate receptor subunit expression in the hippocampus and cerebellum in juvenile rats. Neuropharmacology 2005, 48:195-203.
16. Mennerick S., Zorumski C.F. Paired-pulse modulation of fast excitatory synaptic currents in microcultures of rat hippocampal neurons. J. Physiol. 1995, 488:85-101.
17. Monyer H., Burnashev N., Laurie D.J., Sakmann B., Seeburg P.H. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 1994, 12:529-540.
18. Park S.W., Kim N., Yang Y., Seo B., Paeng K.J. Toluene distribution of glue sniffers' biological fluid samples in Korea. J. Forensic Sci. 1998, 43:888-890.
19. Pearson M.A., Hoyme H.E., Seaver L.H., Rimsza M.E. Toluene embryopathy: delineation of the phenotype and comparison with fetal alcohol syndrome. Pediatrics 1994, 93:211-215.
20. Riegel A.C., French E.D. Acute toluene induces biphasic changes in rat spontaneous locomotor activity which are blocked by remoxipride. Pharmacol. Biochem. Behav. 1999, 62:399-402.
21. Scheetz A.J., Constantine-Paton M. Modulation of NMDA receptor function: implications for vertebrate neural development. FASEB J. 1994, 8:745-752.
22. Shelton K.L., Slavova-Hernandez G. Characterization of an inhaled toluene drug discrimination in mice: effect of exposure conditions and route of administration. Pharmacol. Biochem. Behav. 2009, 92:614-620.
23. Shumilina A.V. The experimental transplacental passage of dimethylformamide and toluene. Akush. Ginekol. (Mosk) 1991, 49-51.
24. Spear L.P. The adolescent brain and age-related behavioral manifestations. Neurosci. Biobehav. Rev. 2000, 24:417-463.
25. Thompson C.L., Drewery D.L., Atkins H.D., Stephenson F.A., Chazot P.L. Immunohistochemical localization of N-methyl-d-aspartate receptor subunits in the adult murine hippocampal formation: evidence for a unique role of the NR2D subunit. Brain Res. Mol. Brain Res. 2002, 102:55-61.
26. Tovar K.R., Westbrook G.L. The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro. J. Neurosci. 1999, 19:4180-4188.
27. Wang J.H., Kelly P.T. Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms. J. Neurophysiol. 1997, 78:2707-2716.
28. Zanatta M.S., Schaeffer E., Schmitz P.K., Medina J.H., Quevedo J., Quillfeldt J.A., Izquierdo I. Sequential involvement of NMDA receptor-dependent processes in hippocampus, amygdala, entorhinal cortex and parietal cortex in memory processing. Behav. Pharmacol. 1996, 7:341-345.
29. Zucker R.S., Regehr W.G. Short-term synaptic plasticity. Annu. Rev. Physiol. 2002, 64:355-405.