Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: Evidence for altered adiponectin signalling

Diabetologia

Volumn 54, Issue 8, 2011, Pages 2122-2131

  Holmes, R M ^a,b   Yi, Z ^b   De Filippis, E ^a,b   Berria, R ^a   Shahani, S ^d   Sathyanarayana, P ^d   Sherman, V ^d   Fujiwara, K ^a,b   Meyer, C ^b   Christ Roberts, C ^b   Hwang, H ^b   Finlayson, J ^b   Dong, L Q ^a   Mandarino, L J ^b,c   Bajaj, M ^d  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b College of Liberal Arts and Sciences ^*  (United States)

^c MAYO CLINIC   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Adiponectin; APPL1; Obesity; Type 2 diabetes

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR; MEMBRANE PROTEIN; PHOSPHOTYROSINE BINDING DOMAIN AND LEUCINE ZIPPER MOTIF; PLECKSTRIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; FATTY ACID OXIDATION; FEMALE; GEL ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOPRECIPITATION; INSULIN SENSITIVITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADIPONECTIN; ADULT; BLOTTING, WESTERN; DIABETES MELLITUS, TYPE 2; ELECTROPHORESIS; FEMALE; HUMANS; IMMUNOPRECIPITATION; MALE; MASS SPECTROMETRY; OBESITY; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 79960912411     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2173-x     Document Type: Article

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