Hepatic transplantation outcomes for carefully selected cirrhotic patients with hepatocellular carcinoma: Experience at a small- to medium-volume centre

Irish Journal of Medical Science

Volumn 178, Issue 4, 2009, Pages 469-472

  Qasim, A ^a   Zaman, M B ^a   Maguire, D ^a   Geoghegan, J ^a   Gibney, R ^a   Nolan, N ^a   Traynor, O ^a   Hegarty, J ^a   McCormick, P A ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

Author keywords

Hepatic transplantation; Hepatocellular carcinoma; Mortality and retransplantation outcomes; Small , medium and high volume centres

Indexed keywords

ADULT; AGED; ARTICLE; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; LIVER TUMOR; MIDDLE AGED; PATHOLOGY; TREATMENT OUTCOME;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MIDDLE AGED; TREATMENT OUTCOME;

EID: 79960900908     PISSN: 00211265     EISSN: 18634362     Source Type: Journal    
DOI: 10.1007/s11845-009-0333-5     Document Type: Article

References (18)

1. Llovet JM, Fuster J (1999) Bruix J for the Barcelona Clinic Liver Cancer (BCLC) Group. Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation. Hepatology 30:1434-1440. doi:10.1002/hep.510300629
2. Burix J, Sherman M, Llovet J et al (2001) Clinical management of heatocellular carcinoma. Conclusion of the Barcelona 2000 EASL Conference. J Hepatol 35:421-430. doi:10.1016/S0168-8278(01)00130-1 (Pubitemid 32844200)
3. Cillo U, Vitale A, Bassanello M et al (2004) Liver transplantation for the treatment of moderately or well-differentiated hepatocellular carcinoma. Ann Surg 239:150-159. doi:10.1097/01.sla.0000109146.72827.76 (Pubitemid 38176347)
4. Bismuth H, Chiche L, Adam R et al (1993) Liver resection versus transplantation for hepatocellular carcinoma in cirrhotic patients. Ann Surg 218:145-151. doi:10.1097/00000658-199308000-00005 (Pubitemid 23229140)
5. Romani F, Belli LS, Rondinara SF et al (1994) The role of transplantation in small hepatocellular carcinoma complicating cirrhosis of the liver. J Am Coll Surg 178:379-384 (Pubitemid 24113447)
6. Mazzaferro V, Regalia E, Doci R et al (1996) Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334:693-699. doi:10.1056/NEJM199603143341104 (Pubitemid 26079803)
7. Figueras J, Jaurrieta E, Valls C et al (1997) Survival after liver transplantation in cirrhotic patients with and without hepatocellular carcinoma: a comparative study. Hepatology 25:1485089. doi:10.1002/hep.510250629
8. Yao FY, Ferrell L, Bass NM et al (2001) Liver transplantation for hepatocellular carcinoma: expansion of tumor size does not adversely impact survival. Hepatology 33:1394-1403. doi:10.1053/jhep.2001.24563 (Pubitemid 32496976)
9. Marsh JW, Dvuorchik I, Bonham A et al (2000) Is the pathologic TNM staging system for patients with hepatoma predictive of outcome? Cancer 88:538-543. doi:10.1002/(SICI)1097-0142(20000201)88:3〈538::AID- CNCR7〉3.0.CO;2-H (Pubitemid 30056926)
10. Barbara L, Benzi G, Gaiani S et al (1992) Natural history of small untreated hepatocellular carcinoma in cirrhosis: a multivariate analysis of prognostic factors of tumor growth rate and patient survival. Hepatology 16(1):132-137. doi:10.1002/hep.1840160122
11. Sheu JC, Sung JL, Chen DS et al (1985) Growth rate of asymptomatic hepatocellular carcinoma and its clinical implications. Gastroenterology 89(2):259-266
12. Edmondson H, Steiner P (1954) Primary carcinoma of the liver: a study of 100 cases among 48900 necropsies. Cancer 1:462-503. doi:10.1002/1097- 0142(195405)7:3〈462::AID-CNCR2820070308〉3.0.CO;2-E
13. Kalbfleisch JD, Prentice RL (1997) The statistical analysis of failure time data. Wiley, New York
14. Llovet JM, Beaugrand M (2003) Hepatocellular carcinoma: present status and future prospects. J Hepatol 38:S136. doi:10.1016/S0168-8278(02)00432-4
15. Freeman RB, Mithoefer A, Ruthazer R et al (2006) Optimizing staging for hepatocellular carcinoma before liver transplantation: a retrospective analysis of the UNOS/OPTN database. Liver Transpl 12:1504-1511. doi:10.1002/lt.20847 (Pubitemid 44594281)
16. Santoyo J, Suarez MA, Fernandez-Aguilar JL et al (2005) Liver transplantation results for hepatocellular carcinoma applying strict preoperative selection criteria. Transpl Proc 37:1488-1490. doi:10.1016/j. transproceed.2005.02.059 (Pubitemid 40712094)
17. Decaens T, Roudot-Thoraval F, Hadni-Bresson S et al (2006) Impact of UCSF criteria according to pre- and post-OLT tumor features: analysis of 479 patients listed for HCC with a short waiting time. Liver Transpl 12:1761-1769. doi:10.1002/lt.20884 (Pubitemid 44911801)
18. Qasim A, McCormick A, Tajjudin T et al (2007) Improved survival outcomes for orthotopic liver transplantation. Ir Med J 100(3):389-390