Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information

International Journal of Andrology

Volumn 34, Issue 4 PART 2, 2011, Pages

  Edsgard D ^a   Scheel, M ^b   Hansen, N T ^a   Ralfkiaer, U ^c   Jensen, T S ^a   Skakkebaek N E ^b   Brunak, S ^a   Gupta, R ^a   Rajpert De Meyts, E ^b   Ottesen, A M ^b  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b Rigshospitalet   (Denmark)

^c DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

Array comparative genomic hybridization; Familial testicular germ cell cancer; Relaxin peptides; Relaxin receptor; Systems biology

Indexed keywords

RELAXIN; RELAXIN H1; RELAXIN H2; UNCLASSIFIED DRUG;

ADULT; ALGORITHM; ARTICLE; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE DELETION; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GERM CELL TUMOR; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTEGRATIVE MEDICINE; LEYDIG CELL; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SERTOLI CELL; SPERMATID; TUMOR CELL;

ADOLESCENT; ADULT; BASE SEQUENCE; COMPARATIVE GENOMIC HYBRIDIZATION; DNA COPY NUMBER VARIATIONS; FAMILY; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; NEOPLASMS, GERM CELL AND EMBRYONAL; POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PEPTIDE; RELAXIN; SEQUENCE DELETION; TESTICULAR NEOPLASMS;

EID: 79960892751     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2011.01188.x     Document Type: Article

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