Effectiveness of postoperative radiotherapy in patients with small oral and oropharyngeal squamous cell carcinoma and concomitant ipsilateral singular cervical lymph node metastasis (pN1): A meta-analysis

Strahlentherapie und Onkologie

Volumn 187, Issue 6, 2011, Pages 337-343

  Moergel, Maximilian ^a   Meurer, Philipp ^a   Ingel, Katharina ^b   Wendt, Thomas G ^c   Al Nawas, Bilal ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Cancer; Head and neck; Meta analysis; pN1; Prognosis; Radiation

Indexed keywords

BLEOMYCIN; CISPLATIN; METHOTREXATE;

CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CARCINOMA; CARCINOMATOUS LYMPHANGITIS; CERVICAL LYMPH NODE METASTASIS; EXTERNAL VALIDITY; HEAD AND NECK CANCER; HISTOLOGY; HUMAN; INTERNAL VALIDITY; IRRADIATION; LYMPH NODE METASTASIS; META ANALYSIS; MORTALITY; MOUTH CARCINOMA; OROPHARYNX CARCINOMA; OUTCOME ASSESSMENT; POSTOPERATIVE PERIOD; POSTOPERATIVE RADIOTHERAPY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SMALL ORAL SQUAMOUS CELL CARCINOMA; STATISTICAL SIGNIFICANCE; STATISTICS; SYSTEMATIC REVIEW; THERAPY EFFECT; TUMOR VOLUME; ARTICLE; LYMPH NODE; MOUTH TUMOR; OROPHARYNX TUMOR; PATHOLOGY; RISK FACTOR; SQUAMOUS CELL CARCINOMA; SURVIVAL;

CARCINOMA, SQUAMOUS CELL; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MOUTH NEOPLASMS; OROPHARYNGEAL NEOPLASMS; POSTOPERATIVE PERIOD; RISK FACTORS; SURVIVAL ANALYSIS;

EID: 79960878861     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-011-2206-x     Document Type: Review

References (29)

1. Atkins D, Best D, Briss PA et al. Grading quality of evidence and strength of recommendations. BMJ 2004;328:1490.
2. Balermpas P, Hambek M, Seitz O et al. Combined cetuximab and reirradiation for locoregional recurrent and inoperable squamous cell carcinoma of the head and neck. Strahlenther Onkol 2009;185:775-81.
3. Berger B, Belka C, Weinmann M et al. Reirradiation with alternating docetaxel-based chemotherapy for recurrent head and neck squamous cell carcinoma: update of a single-center prospective phase II protocol. Strahlenther Onkol 2010;186:255-61.
4. Bernier J, Domenge C, Ozsahin M et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004;350:1945-52. (Pubitemid 38580197)
5. Bolke E, Gerber PA, Lammering G et al. Development and management of severe cutaneous side effects in head-and-neck cancer patients during concurrent radiotherapy and cetuximab. Strahlenther Onkol 2008;184:105-10. (Pubitemid 351231657)
6. Bonner JA, Harari PM, Giralt J et al. Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival. Lancet Oncol 11:21-8.
7. Chen TC, Wang CT, Ko JY et al. Postoperative radiotherapy for primary early oral tongue cancer with pathologic N1 neck. Head Neck 2010;32: 555-61.
8. Cooper JS, Pajak TF, Forastiere AA et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004;350:1937-44.
9. Driemel O, Ettl T, Kolbl O et al. Outcome and histopathologic regression in oral squamous cell carcinoma after preoperative radiochemotherapy. Strahlenther Onkol 2009;185:296-302.
10. Jackel MC, Ambrosch P, Christiansen H et al. Value of postoperative radiotherapy in patients with pathologic N1 neck disease. Head Neck 2008;30:875-82. (Pubitemid 352008947)
11. Kao J, Lavaf A, Teng MS et al. Adjuvant radiotherapy and survival for patients with node-positive head and neck cancer: an analysis by primary site and nodal stage. Int J Radiat Oncol Biol Phys 2008;71:362-70.
12. Kies MS, Pecaro BC, Gordon LI et al. Preoperative combination chemotherapy for advanced stage head and neck cancer. Promising early results. Am J Surg 1984;148:367-71. (Pubitemid 14037307)
13. Krebsgesellschaft D, Kurzgefasste interdisziplinäre Leitlinien 2008: Empfehlungen zur Diagnostik und Therapie maligner Erkrankungen. 2008: Zuckerschwerdt.
14. Leemans CR, Tiwari R, Nauta JJ et al. Regional lymph node involvement and its significance in the development of distant metastases in head and neck carcinoma. Cancer 1993;71:452-6. (Pubitemid 23021234)
15. Leemans CR, Tiwari R, Nauta JJ et al. Recurrence at the primary site in head and neck cancer and the significance of neck lymph node metastases as a prognostic factor. Cancer 1994;73:187-90. (Pubitemid 24012742)
16. Lundahl RE, Foote RL, Bonner JA et al. Combined neck dissection and postoperative radiation therapy in the management of the high-risk neck: a matched-pair analysis. Int J Radiat Oncol Biol Phys 1998;40:529-34. (Pubitemid 28104220)
17. Mak-Kregar S, Keus RB, Balm AJ et al. Carcinoma of the soft palate and the posterior oropharyngeal wall. Clin Otolaryngol Allied Sci 1994;19:22-7. (Pubitemid 24081610)
18. Moergel M, Jahn-Eimermacher A, Krummenauer F et al. Effectiveness of adjuvant radiotherapy in patients with oropharyngeal and floor of mouth squamous cell carcinoma and concomitant histological verification of singular ipsilateral cervical lymph node metastasis (pN1-state)-a prospective multicenter randomized controlled clinical trial using a comprehensive cohort design. Trials 2009;10:118.
19. Moher D, Cook DJ, Eastwood S et al. Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses. Lancet 1999;354:1896-900.
20. Nath SK, Simpson DR, Rose BS et al. Recent advances in image-guided radiotherapy for head and neck carcinoma. J Oncol 2009;2009:752135.
21. Sessions DG, Spector GJ, Lenox J et al. Analysis of treatment results for floor-of-mouth cancer. Laryngoscope 2000;110(10 Pt 1):1764-72.
22. Sessions DG, Spector GJ, Lenox J et al. Analysis of treatment results for oral tongue cancer. Laryngoscope 2002;112:616-25. (Pubitemid 34285925)
23. Sessions DG, Lenox J, Spector GJ et al. Analysis of treatment results for base of tongue cancer. Laryngoscope 2003;113:1252-61. (Pubitemid 36835575)
24. Snow GB, Annyas AA, van Slooten EA et al. Prognostic factors of neck node metastasis. Clin Otolaryngol Allied Sci 1982;7:185-92. (Pubitemid 12088842)
25. Szabo G, Kreidler J, Hollmann K et al. Intra-arterial preoperative cytostatic treatment versus preoperative irradiation: A prospective, randomized study of lingual and sublingual carcinomas. Cancer 1999;86:1381-6. (Pubitemid 29489768)
26. Tribius S, Kronemann S, Kilic Y et al. Radiochemotherapy including cisplatin alone versus cisplatin + 5-fluorouracil for locally advanced unresectable stage IV squamous cell carcinoma of the head and neck. Strahlenther Onkol 2009;185:675-81.
27. Vikram B, Strong EW, Shah JP et al. Failure in the neck following multi-modality treatment for advanced head and neck cancer. Head Neck Surg 1984;6:724-9. (Pubitemid 14185489)
28. Werner JA, Dunne AA, Ramaswamy A et al. Number and location of radiolabeled, intraoperatively identified sentinel nodes in 48 head and neck cancer patients with clinically staged N0 and N1 neck. Eur Arch Otorhinolaryngol 2002;259:91-6. (Pubitemid 34185609)
29. Wolfensberger M, Zbaeren P, Dulguerov P et al. Surgical treatment of early oral carcinoma-results of a prospective controlled multicenter study. Head Neck 2001;23:525-30. (Pubitemid 32565524)