Trichinella spiralis infection rapidly induces lung inflammatory response. The lung as the site of helminthocytotoxic activity

Immunobiology

Volumn 216, Issue 9, 2011, Pages 1054-1063

  Gentilini, María V ^a   Nuñez, Guillermo G ^a   Roux, María E ^b   Venturiello, Stella M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Helminthocytotoxic activity; Inflammation response; Lung; Mucosal immunology; Trichinella spiralis

Indexed keywords

EOTAXIN; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHIL; FEMALE; HISTOPATHOLOGY; LUNG INFECTION; MAST CELL; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; RAT; TRICHINOSIS;

ANIMALS; ANTIBODIES, HELMINTH; CELLS, CULTURED; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; EOSINOPHILS; FEMALE; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN ISOTYPES; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINAL MUCOSA; LARVA; LUNG; MAST CELLS; PRIMARY CELL CULTURE; RATS; RATS, WISTAR; TISSUE EXTRACTS; TRICHINELLA SPIRALIS; TRICHINELLOSIS;

EID: 79960841852     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2011.02.002     Document Type: Article

References (45)

1. Bartels J., Schlüter C., Richter E., Noso N., Kulke R., Christophers E., Schröder J.M. Human dermal fibroblasts express eotaxin: molecular cloning, mRNA expression, and identification of eotaxin sequence variants. Biochem. Biophys. Res. Commun. 1996, 225:1045-1051.
2. Binaghi R.A., Perrudet-Badoux A., Boussac-Aron Y. Mechanisms of Immune Defense Against Trichinella spiralis Newborn Larvae 1981, 85-89. Reedbooks, Chertsey, Surrey. V. Trichinellosis, C.W. Kim, E.J. Ruitemberg, J.S. Teppema (Eds.).
3. Bruschi F., Solfanelli S., Binaghi R.A. Trichinella spiralis: modifications of the cuticle of the newborn larva during passage through the lung. Exp. Parasitol. 1992, 75:1-9.
4. Bruschi F. The immune response to the parasitic nematode Trichinella and the ways to escape it. From experimental studies to implications for human infection. Curr. Drug Targets Immune Endocr. Metabol. Disord. 2002, 2:269-280.
5. Czerkinsky C.C., Nilsson L.A., Nygren H., Ouchterlony O., Tarkowski A. A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells. J. Immunol. Methods 1983, 65:109-121.
6. Denham D.A., Martínez R.A. Studies with methyridine and Trichinella spiralis. 2. The use of the drug to study the rate of larval production in mice. J. Helminthol. 1970, 44:357-363.
7. Despommier D.D., Gwadz R.W., Hotez P.J., Knirsch C.A. The nematodes. Parasitic Diseases 2005, 105-174. Apple Trees Productions L.L.C, NY. D.D. Despommier, R.W. Gwadz, P.J. Hotez, C.A. Knirsch (Eds.).
8. Dixon H., Blanchard C., Schoolmeester M.L., Yuill N.C., Christie J.W., Rothenberg M.E., Else K.J. The role of Th2 cytokines, chemokines and parasite products in eosinophil recruitment to the gastrointestinal mucosa during helminth infection. Eur. J. Immunol. 2006, 36:1753-1763.
9. Dupouy-Camet J., Bruschi F. Management and diagnosis of human trichinellosis. Guidelines for the Surveillance, Management, Prevention and Control of Trichinellosis 2007, 37-68. FAO/WHO/OIE. J. Dupouy-Camet, K.D. Murrell (Eds.).
10. Dzik J.M., Golos B., Jagielska E., Kapala A., Walajtys-Rode E. Early response of guinea-pig lungs to Trichinella spiralis infection. Parasite Immunol. 2002, 24:369-379.
11. Faubert G.M. Depression of the plaque-forming cells of sheep red blood cells by the newborn larvae of Trichinella spiralis. Immunology 1976, 30:485-489.
12. Faubert G.M. The reversal of the immunodepression phenomenon in trichinellosis and its effect on the life cycle of the parasite. Parasite Immunol. 1982, 4:13-20.
13. Gansmüller A., Anteunis A., Venturiello S.M., Bruschi F., Binaghi R.A. Antibody-dependent in-vitro cytotoxicity of newborn Trichinella spiralis larvae: nature of the cells involved. Parasite Immunol. 1987, 3:281-292.
14. Gottstein B., Pozio E., Nöckler K. Epidemiology, diagnosis, treatment, and control of trichinellosis. Clin. Microbiol. Rev. 2009, 22:127-145.
15. Harley J.P., Gallicchio V. Trichinella spiralis: migration of larvae in the rat. Exp. Parasitol. 1971, 30:11-21.
16. Holmgren J., Czerkinsky C. Mucosal immunity and vaccines. Nat. Med. 2005, 11:545-553.
17. Humbles A.A., Lu B., Friend D.S., Okinaga S., Lora J., Al-Garawi A., Martin T.R., Gerard N.P., Gerard C. The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:1479-1484.
18. Ierna M.X., Scales H.E., Saunders K.L., Lawrence C.E. Mast cells production of IL-4 and TNF may be required for protective and pathological responses in gastrointestinal helminth infection. Mucosal Immunol. 2008, 1:147-155.
19. John A.E., Thomas M.S., Berlin A.A., Lukacs N.W. Temporal production of CCL28 corresponds to eosinophil accumulation and airway hyperreactivity in allergic airway inflammation. Am. J. Pathol. 2005, 166:345-353.
20. Kazura J.W. Host defense mechanisms against nematode parasites: destruction of newborn Trichinella spiralis larvae by human antibodies and granulocytes. J. Infect. Dis. 1981, 143:712-718.
21. Knight P.A., Brown J.K., Pemberton A.S. Innate immune response mechanism in the intestinal epithelium: potential roles for mast cells and goblet cells in the expulsion of adult Trichinella spiralis. Parasitology 2008, 135:655-670.
22. Lamm M.E., Phillips-Quagliata J.M. Origin and homing of intestinal IgA antibody-secreting cells. J. Exp. Med. 2002, 195:5-8.
23. Lilly C.M., Nakamura H., Kesselman H., Nagler-Anderson C., Asano K., Garcia-Zepeda E.A., Rothenberg M.E., Drazen J.M., Luster A.D. Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids. J. Clin. Invest. 1997, 99:1767-1773.
24. Malmassari S.L., Costantino S.N., Iacono R.F., Venturiello S.M. Human serum antibodies against shared antigens of different stages of Trichinella spiralis: relevance of glycan and protein epitopes. Parasitol. Res. 2003, 91:94-99.
25. Mitre E., Nutman T. Basophils, basophilia and helminth infections. Chem. Immunol. Allergy 2006, 90:141-156.
26. Nuñez G.G., Malmassari S.L., Costantino S.N., Venturiello S.M. Immunoelectrotransfer blot assay in acute and chronic human trichinellosis. J. Parasitol. 2000, 86:1121-1124.
27. Nuñez G.G., Gentile T., Calcagno M.L., Venturiello S.M. Increased parasiticide activity against Trichinella spiralis newborn larvae during pregnancy. Parasitol. Res. 2002, 88:661-667.
28. Nuñez G.G., Gentile T., Costantino S.N., Sarchi M.L., Venturiello S.M. In vitro and in vivo effects of progesterone on Trichinella spiralis newborn larvae. Parasitology 2005, 131:1-5.
29. Reece J.J., Siracusa M.C., Scott A.L. Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages. Infect. Immun. 2006, 74:4970-4981.
30. Roux M.E., Marquez M.G., Olmos S., Frecha C.A., Florin-Christensen A. Compartmentalization between gut and lung mucosae in a model of secondary immunodeficiency: effect of thymomodulin. Int. J. Immunopathol. Pharmacol. 2003, 16:151-156.
31. Sainte-Marie G. A paraffin embedding technique for studies employing immunofluorescence. J. Histochem. Cytochem. 1961, 10:250-256.
32. Silveira M.R., Nunes K.P., Cara D.C., Souza D.G., Corrêa A., Teixeira M.M., Negrão-Corrêa D. Infection with Strongyloides venezuelensis induces transient airway eosinophilic inflammation, an increase in immunoglobulin E, and hyperresponsiveness in rats. Infect. Immun. 2002, 70:6263-6272.
33. Suzuki T., Sasaki T., Takagi H., Sato K., Ueda K. The effectors responsible for the gastrointestinal nematode parasite, Trichinella spiralis, expulsion in rats. Parasitol. Res. 2008, 103:1289-1295.
34. Tomasi V.H., Orrea S.C., Raimondi A.R., Itoiz M.E. A new technique for staining mast cells using ferroin. Biotech. Histochem. 2003, 78:255-259.
35. Tomasi V.H., Pérez M.A., Itoiz M.E. Modification of Luna's technique for staining eosinophils in the hamster check pouch. Biotech. Histochem. 2008, 83:147-151.
36. Venturiello S.M., Giambartolomei G.H., Costantino S.N. Immune killing of newborn Trichinella larvae by human leukocytes. Parasite Immunol. 1993, 10:559-564.
37. Venturiello S.M., Giambartolomei G.H., Costantino S.N. Immune cytotoxic activity of human eosinophils against Trichinella spiralis newborn larvae. Parasite Immunol. 1995, 11:555-559.
38. Venturiello S.M., Costantino S.N., Giambartolomei G.H. Blocking anti-Trichinella spiralis antibodies in chronically infected rats. Parasitol. Res. 1996, 82:77-81.
39. Venturiello S.M., Malmassari S.L., Costantino S.N., Nuñez G.G. Cytotoxicity-blocking antibodies in human chronic trichinellosis. Parasitol. Res. 2000, 86:762-767.
40. Venturiello S.M., Verzoletti M.L., Costantino S.N., Forastiero M.A., Roux M.E. Early pulmonary response in rats infected with Trichinella spiralis. Parasitology 2007, 134:281-288.
41. Villavedra M., Carol H., Hjulström M., Holmgren J., Czerkinsky C. " PERFEXT": a direct method for quantitative assessment of cytokine production in vivo at the local level. Res. Immunol. 1997, 148:257-266.
42. Wagner S.D., Montalvo H., Lars Hauschild C., Vanhoose A.M., Wang C.H. Rapidity and multipilicity of synthesis and expression of immunoglobulin isotypes by B lymphocytes in the small intestine. Front. Biosci. 2004, 9:1642-1653.
43. Wang C.H., Bell R.G. Trichinella spiralis: vascular recirculation and organ retention of newborn larvae in rats. Exp. Parasitol. 1986, 62:430-441.
44. Wang C.H., Bell R.G. Characterization of cellular and molecular immune effectors against Trichinella spiralis newborn larvae in vivo. Cell. Mol. Biol. 1992, 38:311-325.
45. Wang C.H., Richards E.M., Bell R.G. Rapid anti-helminthic response of B lymphocytes in the intestinal mucosal tissues of rats. Cell. Immunol. 1999, 193:59-70.