Synthesis of heterocyclic substituted norcantharidin derivatives

Journal of Heterocyclic Chemistry

Volumn 48, Issue 4, 2011, Pages 808-813

  Deng, Liping ^a,b   Yong, Zhang ^a   Tao, Weifeng ^b   Shen, Jianfeng ^c   Wang, Wei ^b  

^a SHAOXING UNIVERSITY   (China)

^b Zhejiang Supor Pharmaceuticals   (China)

^c Zhejiang Zhenyuan Pharmaceutical Co Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (5 METHYLTHIAZOL 2 YL) 4,7 EPOXY 3A,4,7,7ALPHA TETRAHYDRO 1H ISOINDOLE 1,3(2H) DIONE; 2 (THIAZOL 2 YL) 4,7 EPOXY 3A,4,7,7ALPHA TETRAHYDRO 1H ISOINDOLE 1,3(2H) DIONE; 3 (5 METHYLTHIAZOL 2 YLCARBAMOYL) 7 OXABICYCLO[2.2.1]HEPT 5 ENE 2 CARBOXYLIC ACID; 3 (THIAZOL 2 YLCARBAMOYL) 7 OXABICYCLO[2.2.1]HEPT 5 ENE 2 CARBOXYLIC ACID; 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 1 PHENYL 3 (2 CHLOROPHENYL) 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 1 PHENYL 3 (2 PHENYL 2H 1,2,3 TRIAZOL 4 YL) 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 1 PHENYL 3 (2,3-DICHLOROPHENYL) 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 1 PHENYL 3 (QUINOXALIN 2 YL) 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 1,3 DIPHENYL 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; 6 (THIAZOL 2 YL) 4,8 EPOXY 1 PHENYL 3 (2 CHLOROPHENYL) 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; 6 (THIAZOL 2 YL) 4,8 EPOXY 1 PHENYL 3 (2 PHENYL 2H 1,2,3 TRIAZOL 4 YL) 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; 6 (THIAZOL 2 YL) 4,8 EPOXY 1 PHENYL 3 (QUINOXALIN 2 YL) 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; 6 (THIAZOL 2 YL) 4,8 EPOXY 1,3 DIPHENYL 4,4A,6,7A,8,8A HEXAHYDROPYRROLO[3,4 F]INDAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (3 HYDROXY 4 METHOXYPHENYL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (4 (METHYLSULFINYL)PHENYL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (4 CHLOROPHENYL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (4 FLUOROPHENYL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (5 METHYLTHIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (BENZO[D][1,3]DIOXOL 5 YL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (THIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (3 HYDROXY 4 METHOXYPHENYL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (THIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (4 (METHYLSULFINYL)PHENYL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (THIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (4 CHLOROPHENYL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (THIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (4 FLUOROPHENYL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; EXO,EXO 6 (THIAZOL 2 YL) 4,8 EPOXY 3A,4,4A,7A,8,8A HEXAHYDRO 3 (BENZO[D][1,3]DIOXO 5 YL)PYRROLO[3,4 F] 1,2 BENZISOXAZOLE 5,7(1H,3AH) DIONE; HYDRAZONE DERIVATIVE; ISOXAZOLE; NORCANTHARIDIN; OXIME; PYRAZOLE; THIAZOLE; TOSYLCHLORAMIDE SODIUM; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS; SUBSTITUTION REACTION;

EID: 79960834478     PISSN: 0022152X     EISSN: 19435193     Source Type: Journal    
DOI: 10.1002/jhet.596     Document Type: Article

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