Human cytomegalovirus glycoprotein B genotyping from bronchoalveolar lavage specimens

Canadian Journal of Microbiology

Volumn 57, Issue 4, 2011, Pages 273-277

  Bergallo, Massimiliano ^a   Costa, Cristina ^a   Gambarino, Stefano ^a   Tornicelli, Alessandra ^a   Astegiano, Sara ^a   Terlizzi, Maria Elena ^a   Solidoro, Paolo ^a   Cavallo, Rossana ^a  

^a MOLINETTE HOSPITAL   (Italy)

Author keywords

Bronchoalveolar lavage; Glycoprotein b gene polymorphism; Human cytomegalovirus

Indexed keywords

ADULT PATIENTS; BRONCHOALVEOLAR LAVAGE; CLINICAL FEATURES; FAST PCR; GENE POLYMORPHISM; GENES ENCODING; GENOTYPING; HUMAN CYTOMEGALOVIRUS; IN-VITRO; IN-VIVO; RESPIRATORY TRACT;

GENES; POLYMERASE CHAIN REACTION;

GLYCOPROTEINS;

GLYCOPROTEIN B; VIRUS DNA; VIRUS GLYCOPROTEIN;

BIOCHEMISTRY; GENE EXPRESSION; GENOTYPE; IMMUNE SYSTEM; MEDICINE; POLYMERASE CHAIN REACTION; POLYMORPHISM; PROTEIN; PUBLIC HEALTH; RESPIRATORY DISEASE; VIRUS;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CYTOMEGALOVIRUS; IMMUNE STATUS; LOWER RESPIRATORY TRACT; LUNG LAVAGE; LUNG TRANSPLANTATION; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; ORGAN WEIGHT; PNEUMONIA; PREVALENCE; PRIORITY JOURNAL; RESPIRATORY FAILURE; VIRUS LOAD;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRONCHOALVEOLAR LAVAGE FLUID; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; VIRAL ENVELOPE PROTEINS; VIRAL LOAD; YOUNG ADULT;

HUMAN HERPESVIRUS 5;

EID: 79960805175     PISSN: 00084166     EISSN: 14803275     Source Type: Journal    
DOI: 10.1139/w11-014     Document Type: Article

References (26)

1. Arav-Boger, R., Willoughby, R.E., Pass, R.F., Zong, J.C., Jang, W.J., Alcendor, D., and Hayward, G.S. 2002. Polymorphisms of the cytomegalovirus (CMV)-encoded tumor necrosis factor-a and bchemokine receptors in congenital CMV disease. J. Infect. Dis. 186(8): 1057-1064. doi:10.1086/344238.
2. Bauer, C.C., Jaksch, P., Aberle, S.W., Haber, H., Lang, G., Klepetko, W., 2007. Relationship between cytomegalovirus DNA load in epithelial lining fluid and plasma of lung transplant recipients and analysis of coinfection with Epstein-Barr virus and human herpesvirus 6 in the lung compartment. J. Clin. Microbiol. 45 (2): 324-328. doi:10.1128/JCM.01173-06.
3. Britt, W.J., and Vugler, L.G. 1989. Processing of the gp55-116 envelope glycoprotein complex (gB) of human cytomegalovirus. J. Virol. 63(1): 403-410.
4. Chou, S. 1992. Molecular epidemiology of envelope glycoprotein H of human cytomegalovirus. J. Infect. Dis. 166 (3): 604-607.
5. Chou, S.W., and Dennison, K.M. 1991. Analysis of interstrain variation in cytomegalovirus glycoprotein B sequences encoding neutralization-related epitopes. J. Infect. Dis. 163(6): 1229-1234.
6. Coaquette, A., Bourgeois, A., Dirand, C., Varin, A., Chen, W., and Herbein, G. 2004. Mixed cytomegalovirus glycoprotein B genotypes in immunocompromised patients. Clin. Infect. Dis. 39(2): 155-161. doi:10.1086/421496.
7. Costa, C., Elia, M., Astegiano, S., Sidoti, F., Terlizzi, M.E., Solidoro, P., 2008. Quantitative detection of Epstein-Barr virus in bronchoalveolar lavage from transplant and non-transplant patients. Transplantation, 86(10): 1389-1394. doi:10.1097/TP. 0b013e3181890415.
8. Fries, B.C., Chou, S., Boeckh, M., and Torok-Storb, B. 1994. Frequency distribution of cytomegalovirus envelope glycoprotein genotypes in bone marrow transplant recipients. J. Infect. Dis. 169(4): 769-774.
9. Görzer, I., Kerschner, H., Jaksch, P., Bauer, C., Seebacher, G., Klepetko, W., and Puchhammer-Stöckl, E. 2008. Viral load dynamics of individual CMV-genotypes in lung transplant recipients with mixed-genotype infections. J. Med. Virol. 80(8): 1405-1414. doi:10.1002/jmv.21225.
10. Haberland, M., Meyer-König, U., and Hufert, F.T. 1999. Variation within the glycoprotein B gene of human cytomegalovirus is due to homologous recombination. J. Gen. Virol. 80(Pt 6): 1495-1500.
11. Humar, A., Kumar, D., Gilbert, C., and Boivin, G. 2003. Cytomegalovirus (CMV) glycoprotein B genotypes and response to antiviral therapy, in solid-organ-transplant recipients with CMV disease. J. Infect. Dis. 188(4): 581-584. doi:10.1086/377002.
12. Manuel, O., Asberg, A., Pang, X., Rollag, H., Emery, V.C., Preiksaitis, J.K., 2009. Impact of genetic polymorphisms in cytomegalovirus glycoprotein B on outcomes in solid-organ transplant recipients with cytomegalovirus disease. Clin. Infect. Dis. 49(8): 1160-1166. doi:10.1086/605633.
13. Navarro, D., Lennette, E., Tugizov, S., and Pereira, L. 1997. Humoral immune response to functional regions of human cytomegalovirus glycoprotein B. J. Med. Virol. 52(4): 451-459. doi:10.1002/(SICI) 1096-9071(199708)52:4<451::AID-JMV18>3.0.CO;2-J.
14. Nogueira, E., Ozaki, K.S., Tomiyama, H., Câmara, N.O., and Granato, C.F. 2009. Clinical correlations of human cytomegalovirus strains and viral load in kidney transplant recipients. Int. Immunopharmacol. 9(1): 26-31. doi:10.1016/j.intimp.2008.08.020.
15. Pang, X., Humar, A., and Preiksaitis, J.K. 2008. Concurrent genotyping and quantitation of cytomegalovirus gB genotypes in solid organ transplant recipients using a real-time PCR assay. J. Clin. Microbiol. 46(12): 4004-4010. doi:10.1128/JCM.01341-08.
16. Pignatelli, S., Dal Monte, P., Rossini, G., and Landini, M.P. 2004. Genetic polymorphism among human cytomegalovirus (HCMV) wild-type strains. Rev. Med. Virol. 14(6): 383-410. doi:10.1002/rmv.438.
17. Rasmussen, L., Hong, C., Zipeto, D., Morris, S., Sherman, D., Chou, S., 1997. Cytomegalovirus gB genotype distribution differs in human immunodeficiency virus-infected patients and immunocompromised allograft recipients. J. Infect. Dis. 175(1): 179-184.
18. Rasmussen, L., Geissler, A., Cowan, C., Chase, A., and Winters, M. 2002. The genes encoding the gCIII complex of human cytomegalovirus exist in highly diverse combinations in clinical isolates. J. Virol. 76(21): 10841-10848. doi:10.1128/JVI.76.21.10841-10848.2002.
19. Sarcinella, L., Mazzulli, T., Willey, B., and Humar, A. 2002. Cytomegalovirus glycoprotein B genotype does not correlate with outcomes in liver transplant patients. J. Clin. Virol. 24(1-2): 99-105. doi:10.1016/S1386-6532(01)00238-4.
20. Shepp, D.H., Match, M.E., Lipson, S.M., and Pergolizzi, R.G. 1998. A fifth human cytomegalovirus glycoprotein B genotype. Res. Virol. 149(2): 109-114. doi:10.1016/S0923-2516(98)80086-1.
21. Spaete, R.R., Saxena, A., Scott, P.I., Song, G.J., Probert, W.S., Britt, W.J., 1990. Sequence requirements for proteolytic processing of glycoprotein B of human cytomegalovirus strain Towne. J. Virol. 64(6): 2922-2931.
22. Tarragó, D., Quereda, C., and Tenorio, A. 2003. Different cytomegalovirus glycoprotein B genotype distribution in serum and cerebrospinal fluid specimens determined by a novel multiplex nested PCR. J. Clin. Microbiol. 41(7): 2872-2877. doi:10.1128/JCM.41.7.2872-2877.2003.
23. Torok-Storb, B., Boeckh, M., Hoy, C., Leisenring, W., Myerson, D., and Gooley, T. 1997. Association of specific cytomegalovirus genotypes with death from myelosuppression after marrow transplantation. Blood, 90(5): 2097-2102.
24. Tugizov, S., Wang, Y., Qadri, I., Navarro, D., Maidji, E., and Pereira, L. 1995. Mutated forms of human cytomegalovirus glycoprotein B are impaired in inducing syncytium formation. Virology, 209(2): 580-591. doi:10.1006/viro.1995.1290.
25. Vogelberg, C., Meyer-König, U., Hufert, F.T., Kirste, G., and von Laer, D. 1996. Human cytomegalovirus glycoprotein B genotypes in renal transplant recipients. J. Med. Virol. 50(1): 31-34. doi:10.1002/(SICI)1096-9071(199609)50:1<31::AID-JMV7>3.0.CO;2- U.
26. Wu, X., Wang, Y., Xu, Y., Wu, D., Sun, A., Zhu, Z., 2010. Cytomegalovirus glycoprotein B genotype in hematopoietic stem cell transplant patients from China. Biol. Blood Marrow Transplant. 16(5): 647-652. doi:10.1016/j.bbmt.2009.12.001.