Nonsense-mediated mRNA decay caused by a frameshift mutation in a large kindred of type 2 long QT syndrome

Heart Rhythm

Volumn 8, Issue 8, 2011, Pages 1200-1206

  Zarraga, Ignatius Gerardo ^a   Zhang, Li ^b   Stump, Matthew R ^a   Gong, Qiuming ^a   Vincent, G Michael ^c   Zhou, Zhengfeng ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Long QT syndrome; Mutation; Nonsense mediated mRNA decay; Patch clamp; Potassium channel

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; POTASSIUM CHANNEL HERG; PROTEIN;

ARTICLE; CELL STRAIN HEK293; CLINICAL ARTICLE; DISEASE CLASSIFICATION; DISEASE SEVERITY; FEMALE; FRAMESHIFT MUTATION; GENE CONSTRUCT; GENE EXPRESSION; GENETIC SCREENING; GENOTYPE; HETEROZYGOTE; HUMAN; LONG QT SYNDROME; MALE; NONSENSE MEDIATED MRNA DECAY; NONSENSE MUTATION; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RNA INTERFERENCE;

DNA, COMPLEMENTARY; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; FRAMESHIFT MUTATION; GENETIC ASSOCIATION STUDIES; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; LONG QT SYNDROME; MALE; NONSENSE MEDIATED MRNA DECAY; PATCH-CLAMP TECHNIQUES; PEDIGREE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 79960805106     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2011.03.039     Document Type: Article

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