Topical application of povidone-iodine before wound closure is associated with significant increase in serum iodine level

Surgical Practice

Volumn 15, Issue 3, 2011, Pages 79-82

  Wong, Randolph H L ^a   Wong, Vivien W Y ^a   Hung, Emily C W ^b   Lee, Ping Yin ^a   Ng, Calvin S H ^a   Wan, Innes Y P ^a   Underwood, Malcolm J ^a  

^a Division of Breast Surgery   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Antiseptic; Cardiac surgical procedures; Povidone iodine; Wound infection

Indexed keywords

EID: 79960804235     PISSN: 17441625     EISSN: 17441633     Source Type: Journal    
DOI: 10.1111/j.1744-1633.2011.00547.x     Document Type: Article

References (19)

1. Yap EY, Levine A, Strang T etal. Should additional antibiotics or an iodine washout be given to all patients who suffer an emergency re-sternotomy on the cardiothoracic intensive care units? Interact. Cardiovasc. Thorac. Surg. 2008; 7: 464-69.
2. Schneiter D, Grodzki T, Lardinosis D etal. Accelerated treatment of postpneumonectomy empyema: a binational long-term study. J. Thorac. Cardiovasc. Surg. 2008; 136: 17-85.
3. Scully HE, Leclerc Y, Martin RD etal. Comparison between antibiotic irrigation and mobilization of pectoral muscle flaps in treatment of deep sterna infections. J. Thorac. Cardiovasc. Surg. 1985; 90: 523-31.
4. Ohuchi S, Kawazoe K, Ishihara K, Izumoto H, Eishi K. Management with close irrigation for post-sternotomy mediastinitis: experience with the use of electrolyzed strong acid aqueous solution. Jpn. J. Thorac. Cardiovasc. Surg. 2003; 51: 511-14.
5. Pietsch J, Meakins JL. Complications of povidone-iodine absorption in topically treated burn patients. Lancet 1976; 1: 280-2.
6. Wong RH, Hung EC, Wong VW etal. Povidone-iodine wound irrigation: a word of caution. Surg. Pract. 2009; 13: 123-4.
7. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann. Intern. Med. 1999; 130: 461-70.
8. Sindelar WF, Mason GR. Irrigation of subcutaneous tissue with povidone-iodine solution for prevention of surgical wound infections. Surg. Gynecol. Obstet. 1979; 148: 227-31.
9. Yeginsu A, Karamustafaoglu A, Ozugurlu F, Etikan I. Iodopovidone pleurodesis does not affect thyroid function in normal adults. Interact. Cardiovasc. Thorac. Surg. 2007; 6: 563-4.
10. Kataoka M, Tsumura H, Kaku N, Torisu T. Toxic effects of povidone-iodine on synovial cell and articular cartilage. Clin. Rheumatol. 2006; 25: 632-8.
11. Tsunoda A, Shibusawa M, Tsunoda Y, Kamiyama G, Yamazaki K, Kusano M. Effect of povidone-iodine on anastomotic tumor growth in an experimental model of colorectal cancer surgery. Anticancer Res. 1999; 19: 1149-52.
12. Balin AK, Pratt L. Dilute povidone-iodine solutions inhibit human skin fobroblast growth. Dermatol. Surg. 2002; 28: 210-14.
13. Lowe DO, Knowles SR, Weber EA, Railton CJ, Shear NH. Povidone-iodine induced burn: case report and review of the literature. Pharmacotherapy 2006; 26: 1641-5.
14. de Jong TE, Vierhout RJ, va Vroonhoven TJ. Povidone-iodine irrigation of the subcutaneous tissue to prevent surgical wound infections. Surg. Gynecol. Obstet. 1982; 155: 221-4.
15. Rogers DM, Blouin GS, O'Leary JP. Povidone-iodine wound irrigation and wound sepsis. Surg. Gynecol. Obstet. 1983; 157: 426-30.
16. Vallance S, Waldron R. Antiseptic vs. saline lavage in purulent and faecal peritonitis. J. Hosp. Infect. 1985; 6 (Suppl): 87-91.
17. Glick PL, Guglielmo BJ, Tranbaugh RF, Turley K. Iodine toxicity in a patient treated by continuous povidone-iodine mediatinal irrigation. Ann. Thorac. Surg. 1985; 39: 478-80.
18. Kanakiriya S, De Chazal I, Nath KA, Haugen EN, Albright RC, Juncos LA. Iodine toxicity treated with hemodialysis and continuous venovenous hemodiafiltration. Am. J. Kidney Dis. 2003; 41: 702-8.
19. Ko W, Lazenby WD, Zelano JA, Isom OW, Krieger KH. Effects of shaving methods and intra-operative irrigation on suppurative mediastinitis after bypass operations. Ann. Thorac. Surg. 1992; 53: 301-5.