Long-term treatment with eicosapentaenoic acid ameliorates myocardial ischemia-reperfusion injury in pigs in vivo: Involvement of rho-kinase pathway inhibition

Circulation Journal

Volumn 75, Issue 8, 2011, Pages 1843-1851

  Gao, Jun Yi ^a   Yasuda, Satoshi ^a   Tsuburaya, Ryuji ^a   Ito, Yoshitaka ^a   Shiroto, Takashi ^a   Hao, Kiyotaka ^a   Aizawa, Kentaro ^a   Kikuchi, Yoku ^a   Ito, Kenta ^a   Shimokawa, Hiroaki ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Eicosapentaenoic acid (EPA); Inflammation; Nitric oxide; Reperfusion

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ICOSAPENTAENOIC ACID; RHO KINASE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; ERYTHROCYTE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE ISCHEMIA; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE WALL MOTION; IN VIVO STUDY; INFLAMMATORY INFILTRATE; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SWINE;

ANIMALS; CARDIOTONIC AGENTS; EICOSAPENTAENOIC ACID; ERYTHROCYTES; HEART VENTRICLES; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NITRIC OXIDE SYNTHASE TYPE III; RHO-ASSOCIATED KINASES; STROKE VOLUME; SWINE; TIME FACTORS;

EID: 79960790541     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-11-0209     Document Type: Article

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