Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis

Human Molecular Genetics

Volumn 20, Issue 16, 2011, Pages 3129-3137

  Bijlmakers, Marie José ^a,b   Kanneganti, Seshu K ^a   Barker, Jonathan N ^a   Trembath, Richard C ^a   Capon, Francesca ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DOUBLE STRANDED RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 23; RETINOIC ACID INDUCIBLE PROTEIN I; RNF114 PROTEIN; UBIQUITINATED PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; FUNCTIONAL GENOMICS; GENE ACTIVATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; INNATE IMMUNITY; MOLECULAR PATHOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PSORIASIS; SIGNAL TRANSDUCTION;

CARRIER PROTEINS; CELL LINE; CYTOPLASM; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNITY, INNATE; INTERFERONS; POLY I-C; PROTEIN BINDING; PROTEIN TRANSPORT; PSORIASIS; RNA, DOUBLE-STRANDED; SOLUBILITY; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATED PROTEINS; UP-REGULATION;

EID: 79960784297     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr215     Document Type: Article

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