Strategies for H-score normalization of preanalytical technical variables with potential utility to immunohistochemical-based biomarker quantitation in therapeutic reponse diagnostics

Analytical Cellular Pathology

Volumn 34, Issue 3, 2011, Pages 159-168

  Pierceall, William E ^a   Wolfe, Michele ^a   Suschak, Jessica ^a   Chang, Hua ^a   Chen, Yan ^a   Sprott, Kam M ^a   Kutok, Jeffery L ^b,c   Quan, Stella ^a   Weaver, David T ^a   Ward, Brian E ^a  

^a On Q ity Inc ^*  (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Infinity Pharmaceuticals Inc   (United States)

Author keywords

biomarker; fixation; IHC; preanalytical variation; theranostics

Indexed keywords

ATM PROTEIN; BRCA1 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; SNRNP70 PROTEIN; SNRPA PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG;

ADULT; ANALYTICAL PARAMETERS; ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CONTROLLED STUDY; DIAGNOSTIC VALUE; FEMALE; H SCORE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE MICROARRAY;

BREAST NEOPLASMS; CALIBRATION; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR; TIME FACTORS; TISSUE ARRAY ANALYSIS; TISSUE FIXATION; TUMOR MARKERS, BIOLOGICAL;

EID: 79960780833     PISSN: 22107177     EISSN: 22107185     Source Type: Journal    
DOI: 10.1155/2011/583182     Document Type: Article

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