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Volumn 3, Issue 7, 2011, Pages 982-1000

Correlates of immunity to filovirus infection

Author keywords

Ebola; Filovirus; Immunity; Marburg

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; FILOVIRUS VACCINE; GAMMA INTERFERON; HLA ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS VACCINE;

EID: 79960755551     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v3070982     Document Type: Review
Times cited : (33)

References (125)
  • 1
    • 50649111431 scopus 로고    scopus 로고
    • Filoviruses. A compendium of 40 years of epidemiological, clinical, and laboratory studies
    • Kuhn, J.H. Filoviruses. A compendium of 40 years of epidemiological, clinical, and laboratory studies. Arch. Virol. Suppl. 2008, 20, 13-360.
    • (2008) Arch. Virol. Suppl , vol.20 , pp. 13-360
    • Kuhn, J.H.1
  • 5
    • 38449085116 scopus 로고    scopus 로고
    • Spatial and temporal patterns of Zaire ebolavirus antibody prevalence in the possible reservoir bat species
    • Pourrut, X.; Delicat, A.; Rollin, P.E.; Ksiazek, T.G.; Gonzalez, J.P.; Leroy, E.M. Spatial and temporal patterns of Zaire ebolavirus antibody prevalence in the possible reservoir bat species. J. Infect. Dis. 2007, 196, S176-S183.
    • (2007) J. Infect. Dis , vol.196
    • Pourrut, X.1    Delicat, A.2    Rollin, P.E.3    Ksiazek, T.G.4    Gonzalez, J.P.5    Leroy, E.M.6
  • 6
    • 70449580483 scopus 로고    scopus 로고
    • Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus
    • Pourrut, X.; Souris, M.; Towner, J.S.; Rollin, P.E.; Nichol, S.T.; Gonzalez, J.P.; Leroy, E. Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus. BMC Infect. Dis. 2009, 9, 159.
    • (2009) BMC Infect Dis , vol.9 , pp. 159
    • Pourrut, X.1    Souris, M.2    Towner, J.S.3    Rollin, P.E.4    Nichol, S.T.5    Gonzalez, J.P.6    Leroy, E.7
  • 8
    • 79959345325 scopus 로고    scopus 로고
    • Filovirius vaccines
    • accessed on 16 June 2011
    • Bradfute, S.B.; Dye, J.M., Jr.; Bavari, S. Filovirius vaccines. Hum. Vaccin. 2011, 7. Available online: http://www.landesbioscience.com/journals/vaccines/article/15398/ (accessed on 16 June 2011).
    • (2011) Hum. Vaccin , vol.7
    • Bradfute, S.B.1    Dye Jr., J.M.2    Bavari, S.3
  • 10
    • 77952680862 scopus 로고    scopus 로고
    • Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: A proof-of-concept study
    • Geisbert, T.W.; Lee, A.C.; Robbins, M.; Geisbert, J.B.; Honko, A.N.; Sood, V.; Johnson, J.C.; de Jong, S.; Tavakoli, I.; Judge, A., et al. Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: A proof-of-concept study. Lancet 2010, 375, 1896-1905.
    • (2010) Lancet , vol.375 , pp. 1896-1905
    • Geisbert, T.W.1    Lee, A.C.2    Robbins, M.3    Geisbert, J.B.4    Honko, A.N.5    Sood, V.6    Johnson, J.C.7    de Jong, S.8    Tavakoli, I.9    Judge, A.10
  • 11
    • 0031688699 scopus 로고    scopus 로고
    • A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever
    • Bray, M.; Davis, K.; Geisbert, T.; Schmaljohn, C.; Huggins, J. A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever. J. Infect. Dis. 1998, 178, 651-661.
    • (1998) J. Infect. Dis , vol.178 , pp. 651-661
    • Bray, M.1    Davis, K.2    Geisbert, T.3    Schmaljohn, C.4    Huggins, J.5
  • 13
    • 0031442448 scopus 로고    scopus 로고
    • Antigenicity and vaccine potential of Marburg virus glycoprotein expressed by baculovirus recombinants
    • Hevey, M.; Negley, D.; Geisbert, J.; Jahrling, P.; Schmaljohn, A. Antigenicity and vaccine potential of Marburg virus glycoprotein expressed by baculovirus recombinants. Virology 1997, 239, 206-216.
    • (1997) Virology , vol.239 , pp. 206-216
    • Hevey, M.1    Negley, D.2    Geisbert, J.3    Jahrling, P.4    Schmaljohn, A.5
  • 14
    • 0014233863 scopus 로고
    • The aetiology of an unknown human infection transmitted by monkeys (preliminary communication)
    • Siegert, R.; Shu, H.L.; Slenczka, H.L.; Peters, D.; Muller, G. The aetiology of an unknown human infection transmitted by monkeys (preliminary communication). Ger. Med. Mon. 1968, 13, 1-2.
    • (1968) Ger. Med. Mon , vol.13 , pp. 1-2
    • Siegert, R.1    Shu, H.L.2    Slenczka, H.L.3    Peters, D.4    Muller, G.5
  • 17
    • 0034993883 scopus 로고    scopus 로고
    • The role of the Type I interferon response in the resistance of mice to filovirus infection
    • Bray, M. The role of the Type I interferon response in the resistance of mice to filovirus infection. J. Gen. Virol. 2001, 82, 1365-1373.
    • (2001) J. Gen. Virol , vol.82 , pp. 1365-1373
    • Bray, M.1
  • 19
    • 0034096583 scopus 로고    scopus 로고
    • Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-L-homocysteine hydrolase inhibitor
    • Bray, M.; Driscoll, J.; Huggins, J.W. Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-L-homocysteine hydrolase inhibitor. Antivir. Res. 2000, 45, 135-147.
    • (2000) Antivir. Res , vol.45 , pp. 135-147
    • Bray, M.1    Driscoll, J.2    Huggins, J.W.3
  • 20
    • 0035997942 scopus 로고    scopus 로고
    • 3-deazaneplanocin A induces massively increased interferon-alpha production in Ebola virus-infected mice
    • Bray, M.; Raymond, J.L.; Geisbert, T.; Baker, R.O. 3-deazaneplanocin A induces massively increased interferon-alpha production in Ebola virus-infected mice. Antivir. Res. 2002, 55, 151-159.
    • (2002) Antivir. Res , vol.55 , pp. 151-159
    • Bray, M.1    Raymond, J.L.2    Geisbert, T.3    Baker, R.O.4
  • 23
    • 67650866693 scopus 로고    scopus 로고
    • Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery
    • Chang, T.H.; Kubota, T.; Matsuoka, M.; Jones, S.; Bradfute, S.B.; Bray, M.; Ozato, K. Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery. PLoS Pathog. 2009, 5, e1000493.
    • (2009) PLoS Pathog , vol.5
    • Chang, T.H.1    Kubota, T.2    Matsuoka, M.3    Jones, S.4    Bradfute, S.B.5    Bray, M.6    Ozato, K.7
  • 24
    • 0033870894 scopus 로고    scopus 로고
    • Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein
    • Talon, J.; Horvath, C.M.; Polley, R.; Basler, C.F.; Muster, T.; Palese, P.; Garcia-Sastre, A. Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. J. Virol. 2000, 74, 7989-7996.
    • (2000) J. Virol , vol.74 , pp. 7989-7996
    • Talon, J.1    Horvath, C.M.2    Polley, R.3    Basler, C.F.4    Muster, T.5    Palese, P.6    Garcia-Sastre, A.7
  • 26
    • 26244437083 scopus 로고    scopus 로고
    • Homo-oligomerization facilitates the interferon-antagonist activity of the ebolavirus VP35 protein
    • Reid, S.P.; Cardenas, W.B.; Basler, C.F. Homo-oligomerization facilitates the interferon-antagonist activity of the ebolavirus VP35 protein. Virology 2005, 341, 179-189.
    • (2005) Virology , vol.341 , pp. 179-189
    • Reid, S.P.1    Cardenas, W.B.2    Basler, C.F.3
  • 27
    • 73849109409 scopus 로고    scopus 로고
    • Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling
    • Mateo, M.; Reid, S.P.; Leung, L.W.; Basler, C.F.; Volchkov, V.E. Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling. J. Virol. 2010, 84, 1169-1175.
    • (2010) J. Virol , vol.84 , pp. 1169-1175
    • Mateo, M.1    Reid, S.P.2    Leung, L.W.3    Basler, C.F.4    Volchkov, V.E.5
  • 28
    • 37149040796 scopus 로고    scopus 로고
    • Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1
    • Reid, S.P.; Valmas, C.; Martinez, O.; Sanchez, F.M.; Basler, C.F. Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. J. Virol. 2007, 81, 13469-13477.
    • (2007) J. Virol , vol.81 , pp. 13469-13477
    • Reid, S.P.1    Valmas, C.2    Martinez, O.3    Sanchez, F.M.4    Basler, C.F.5
  • 30
    • 63149113399 scopus 로고    scopus 로고
    • Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1
    • Prins, K.C.; Cardenas, W.B.; Basler, C.F. Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. J. Virol. 2009, 83, 3069-3077.
    • (2009) J. Virol , vol.83 , pp. 3069-3077
    • Prins, K.C.1    Cardenas, W.B.2    Basler, C.F.3
  • 32
    • 76249118239 scopus 로고    scopus 로고
    • The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide
    • Jin, H.; Yan, Z.; Prabhakar, B.S.; Feng, Z.; Ma, Y.; Verpooten, D.; Ganesh, B.; He, B. The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide. J. Gen. Virol. 2010, 91, 352-361.
    • (2010) J. Gen. Virol , vol.91 , pp. 352-361
    • Jin, H.1    Yan, Z.2    Prabhakar, B.S.3    Feng, Z.4    Ma, Y.5    Verpooten, D.6    Ganesh, B.7    He, B.8
  • 33
    • 33845728488 scopus 로고    scopus 로고
    • The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR
    • Feng, Z.; Cerveny, M.; Yan, Z.; He, B. The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR. J. Virol. 2007, 81, 182-192.
    • (2007) J. Virol , vol.81 , pp. 182-192
    • Feng, Z.1    Cerveny, M.2    Yan, Z.3    He, B.4
  • 34
    • 43949091157 scopus 로고    scopus 로고
    • Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein
    • Hartman, A.L.; Ling, L.; Nichol, S.T.; Hibberd, M.L. Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein. J. Virol. 2008, 82, 5348-5358.
    • (2008) J. Virol , vol.82 , pp. 5348-5358
    • Hartman, A.L.1    Ling, L.2    Nichol, S.T.3    Hibberd, M.L.4
  • 35
    • 40149109042 scopus 로고    scopus 로고
    • Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus
    • Hartman, A.L.; Bird, B.H.; Towner, J.S.; Antoniadou, Z.A.; Zaki, S.R.; Nichol, S.T. Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus. J. Virol. 2008, 82, 2699-2704.
    • (2008) J. Virol , vol.82 , pp. 2699-2704
    • Hartman, A.L.1    Bird, B.H.2    Towner, J.S.3    Antoniadou, Z.A.4    Zaki, S.R.5    Nichol, S.T.6
  • 37
    • 79955407974 scopus 로고    scopus 로고
    • Marburgvirus VP40 antagonizes IFN signaling in a species-specific manner
    • Valmas, C.; Basler, C.F. Marburgvirus VP40 antagonizes IFN signaling in a species-specific manner. J. Virol. 2011, 85, 4309-4317.
    • (2011) J. Virol , vol.85 , pp. 4309-4317
    • Valmas, C.1    Basler, C.F.2
  • 38
    • 80053929813 scopus 로고    scopus 로고
    • Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells
    • doi:10.1038/icb.2010.169
    • Leung, L.W.; Park, M.S.; Martinez, O.; Valmas, C.; Lopez, C.B.; Basler, C.F. Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells. Immunol. Cell Biol. 2011, doi:10.1038/icb.2010.169.
    • (2011) Immunol. Cell Biol
    • Leung, L.W.1    Park, M.S.2    Martinez, O.3    Valmas, C.4    Lopez, C.B.5    Basler, C.F.6
  • 42
    • 78449261317 scopus 로고    scopus 로고
    • Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis
    • Wauquier, N.; Becquart, P.; Padilla, C.; Baize, S.; Leroy, E.M. Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis. PLoS Negl. Trop. Dis. 2010, 4, e837.
    • (2010) PLoS Negl. Trop. Dis , vol.4
    • Wauquier, N.1    Becquart, P.2    Padilla, C.3    Baize, S.4    Leroy, E.M.5
  • 43
    • 0032997843 scopus 로고    scopus 로고
    • Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection
    • Villinger, F.; Rollin, P.E.; Brar, S.S.; Chikkala, N.F.; Winter, J.; Sundstrom, J.B.; Zaki, S.R.; Swanepoel, R.; Ansari, A.A.; Peters, C.J. Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection. J. Infect. Dis. 1999, 179, S188-S191.
    • (1999) J. Infect. Dis , vol.179
    • Villinger, F.1    Rollin, P.E.2    Brar, S.S.3    Chikkala, N.F.4    Winter, J.5    Sundstrom, J.B.6    Zaki, S.R.7    Swanepoel, R.8    Ansari, A.A.9    Peters, C.J.10
  • 44
    • 44449096726 scopus 로고    scopus 로고
    • IL-10: The master regulator of immunity to infection
    • Couper, K.N.; Blount, D.G.; Riley, E.M. IL-10: The master regulator of immunity to infection. J. Immunol. 2008, 180, 5771-5777.
    • (2008) J. Immunol , vol.180 , pp. 5771-5777
    • Couper, K.N.1    Blount, D.G.2    Riley, E.M.3
  • 46
    • 0036498098 scopus 로고    scopus 로고
    • Proinflammatory response during Ebola virus infection of primate models: Possible involvement of the tumor necrosis factor receptor superfamily
    • Hensley, L.E.; Young, H.A.; Jahrling, P.B.; Geisbert, T.W. Proinflammatory response during Ebola virus infection of primate models: Possible involvement of the tumor necrosis factor receptor superfamily. Immunol. Lett. 2002, 80, 169-179.
    • (2002) Immunol. Lett , vol.80 , pp. 169-179
    • Hensley, L.E.1    Young, H.A.2    Jahrling, P.B.3    Geisbert, T.W.4
  • 48
    • 0034798175 scopus 로고    scopus 로고
    • Multiplex analysis of cytokines in the blood of cynomolgus macaques naturally infected with Ebola virus (Reston serotype)
    • Hutchinson, K.L.; Villinger, F.; Miranda, M.E.; Ksiazek, T.G.; Peters, C.J.; Rollin, P.E. Multiplex analysis of cytokines in the blood of cynomolgus macaques naturally infected with Ebola virus (Reston serotype). J. Med. Virol. 2001, 65, 561-566.
    • (2001) J. Med. Virol , vol.65 , pp. 561-566
    • Hutchinson, K.L.1    Villinger, F.2    Miranda, M.E.3    Ksiazek, T.G.4    Peters, C.J.5    Rollin, P.E.6
  • 51
    • 0030062139 scopus 로고    scopus 로고
    • Inactivated Marburg virus elicits a nonprotective immune response in Rhesus monkeys
    • Ignatyev, G.M.; Agafonov, A.P.; Streltsova, M.A.; Kashentseva, E.A. Inactivated Marburg virus elicits a nonprotective immune response in Rhesus monkeys. J. Biotechnol. 1996, 44, 111-118.
    • (1996) J. Biotechnol , vol.44 , pp. 111-118
    • Ignatyev, G.M.1    Agafonov, A.P.2    Streltsova, M.A.3    Kashentseva, E.A.4
  • 53
    • 38449099004 scopus 로고    scopus 로고
    • Cytokine and chemokine expression in humans infected with Sudan Ebola virus
    • Hutchinson, K.L.; Rollin, P.E. Cytokine and chemokine expression in humans infected with Sudan Ebola virus. J. Infect. Dis. 2007, 196, S357-S363.
    • (2007) J. Infect. Dis , vol.196
    • Hutchinson, K.L.1    Rollin, P.E.2
  • 54
    • 4544228226 scopus 로고    scopus 로고
    • Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: Cellular responses, virus load, and nitric oxide levels
    • Sanchez, A.; Lukwiya, M.; Bausch, D.; Mahanty, S.; Sanchez, A.J.; Wagoner, K.D.; Rollin, P.E. Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: Cellular responses, virus load, and nitric oxide levels. J. Virol. 2004, 78, 10370-10377.
    • (2004) J. Virol , vol.78 , pp. 10370-10377
    • Sanchez, A.1    Lukwiya, M.2    Bausch, D.3    Mahanty, S.4    Sanchez, A.J.5    Wagoner, K.D.6    Rollin, P.E.7
  • 55
    • 0043166564 scopus 로고    scopus 로고
    • Protection from lethal infection is determined by innate immune responses in a mouse model of Ebola virus infection
    • Mahanty, S.; Gupta, M.; Paragas, J.; Bray, M.; Ahmed, R.; Rollin, P.E. Protection from lethal infection is determined by innate immune responses in a mouse model of Ebola virus infection. Virology 2003, 312, 415-424.
    • (2003) Virology , vol.312 , pp. 415-424
    • Mahanty, S.1    Gupta, M.2    Paragas, J.3    Bray, M.4    Ahmed, R.5    Rollin, P.E.6
  • 57
    • 0018188505 scopus 로고
    • Report of a WHO/International Study Team
    • Ebola haemorrhagic fever in Sudan
    • Ebola haemorrhagic fever in Sudan, 1976. Report of a WHO/International Study Team. Bull. World Health Organ. 1978, 56, 247-270.
    • (1976) Bull. World Health Organ , vol.1978 , Issue.56 , pp. 247-270
  • 58
    • 0018104527 scopus 로고
    • World Health Organization International Study Team. Ebola haemorrhagic fever in Zaire
    • World Health Organization International Study Team. Ebola haemorrhagic fever in Zaire, 1976. Bull. World Health Organ. 1978, 56, 271-293.
    • (1976) Bull. World Health Organ , vol.1978 , Issue.56 , pp. 271-293
  • 60
    • 44849135333 scopus 로고    scopus 로고
    • Functional CD8+ T cell responses in lethal Ebola virus infection
    • Bradfute, S.B.; Warfield, K.L.; Bavari, S. Functional CD8+ T cell responses in lethal Ebola virus infection. J. Immunol. 2008, 180, 4058-4066.
    • (2008) J. Immunol , vol.180 , pp. 4058-4066
    • Bradfute, S.B.1    Warfield, K.L.2    Bavari, S.3
  • 61
  • 62
    • 4544293451 scopus 로고    scopus 로고
    • Depletion of peripheral blood T lymphocytes and NK cells during the course of ebola hemorrhagic Fever in cynomolgus macaques
    • Reed, D.S.; Hensley, L.E.; Geisbert, J.B.; Jahrling, P.B.; Geisbert, T.W. Depletion of peripheral blood T lymphocytes and NK cells during the course of ebola hemorrhagic Fever in cynomolgus macaques. Viral. Immunol. 2004, 17, 390-400.
    • (2004) Viral. Immunol , vol.17 , pp. 390-400
    • Reed, D.S.1    Hensley, L.E.2    Geisbert, J.B.3    Jahrling, P.B.4    Geisbert, T.W.5
  • 63
    • 0034066642 scopus 로고    scopus 로고
    • Apoptosis in fatal Ebola infection. Does the virus toll the bell for immune system?
    • Baize, S.; Leroy, E.M.; Mavoungou, E.; Fisher-Hoch, S.P. Apoptosis in fatal Ebola infection. Does the virus toll the bell for immune system? Apoptosis 2000, 5, 5-7.
    • (2000) Apoptosis , vol.5 , pp. 5-7
    • Baize, S.1    Leroy, E.M.2    Mavoungou, E.3    Fisher-Hoch, S.P.4
  • 65
    • 0345445900 scopus 로고    scopus 로고
    • Pathogenesis of Ebola hemorrhagic fever in primate models: Evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells
    • Geisbert, T.W.; Young, H.A.; Jahrling, P.B.; Davis, K.J.; Larsen, T.; Kagan, E.; Hensley, L.E. Pathogenesis of Ebola hemorrhagic fever in primate models: Evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells. Am. J. Pathol. 2003, 163, 2371-2382.
    • (2003) Am. J. Pathol , vol.163 , pp. 2371-2382
    • Geisbert, T.W.1    Young, H.A.2    Jahrling, P.B.3    Davis, K.J.4    Larsen, T.5    Kagan, E.6    Hensley, L.E.7
  • 68
    • 12144288615 scopus 로고    scopus 로고
    • Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome
    • Towner, J.S.; Rollin, P.E.; Bausch, D.G.; Sanchez, A.; Crary, S.M.; Vincent, M.; Lee, W.F.; Spiropoulou, C.F.; Ksiazek, T.G.; Lukwiya, M., et al. Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome. J. Virol. 2004, 78, 4330-4341.
    • (2004) J. Virol , vol.78 , pp. 4330-4341
    • Towner, J.S.1    Rollin, P.E.2    Bausch, D.G.3    Sanchez, A.4    Crary, S.M.5    Vincent, M.6    Lee, W.F.7    Spiropoulou, C.F.8    Ksiazek, T.G.9    Lukwiya, M.10
  • 70
    • 0141958123 scopus 로고    scopus 로고
    • Selective depletion of nonspecific T cells during the early stage of immune responses to infection
    • Jiang, J.; Lau, L.L.; Shen, H. Selective depletion of nonspecific T cells during the early stage of immune responses to infection. J. Immunol. 2003, 171, 4352-4358.
    • (2003) J. Immunol , vol.171 , pp. 4352-4358
    • Jiang, J.1    Lau, L.L.2    Shen, H.3
  • 71
    • 0034968096 scopus 로고    scopus 로고
    • Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses
    • McNally, J.M.; Zarozinski, C.C.; Lin, M.Y.; Brehm, M.A.; Chen, H.D.; Welsh, R.M. Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses. J. Virol. 2001, 75, 5965-5976.
    • (2001) J. Virol , vol.75 , pp. 5965-5976
    • McNally, J.M.1    Zarozinski, C.C.2    Lin, M.Y.3    Brehm, M.A.4    Chen, H.D.5    Welsh, R.M.6
  • 73
    • 38449100363 scopus 로고    scopus 로고
    • Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge
    • Warfield, K.L.; Swenson, D.L.; Olinger, G.G.; Kalina, W.V.; Aman, M.J.; Bavari, S. Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge. J. Infect. Dis. 2007, 196, S430-S437.
    • (2007) J. Infect. Dis , vol.196
    • Warfield, K.L.1    Swenson, D.L.2    Olinger, G.G.3    Kalina, W.V.4    Aman, M.J.5    Bavari, S.6
  • 75
    • 0032506208 scopus 로고    scopus 로고
    • Marburg virus vaccines based upon alphavirus replicons protect guinea pigs and nonhuman primates
    • Hevey, M.; Negley, D.; Pushko, P.; Smith, J.; Schmaljohn, A. Marburg virus vaccines based upon alphavirus replicons protect guinea pigs and nonhuman primates. Virology 1998, 251, 28-37.
    • (1998) Virology , vol.251 , pp. 28-37
    • Hevey, M.1    Negley, D.2    Pushko, P.3    Smith, J.4    Schmaljohn, A.5
  • 78
    • 0034735774 scopus 로고    scopus 로고
    • Development of a preventive vaccine for Ebola virus infection in primates
    • Sullivan, N.J.; Sanchez, A.; Rollin, P.E.; Yang, Z.Y.; Nabel, G.J. Development of a preventive vaccine for Ebola virus infection in primates. Nature 2000, 408, 605-609.
    • (2000) Nature , vol.408 , pp. 605-609
    • Sullivan, N.J.1    Sanchez, A.2    Rollin, P.E.3    Yang, Z.Y.4    Nabel, G.J.5
  • 80
    • 64749097604 scopus 로고    scopus 로고
    • Correlates of protective immunity for Ebola vaccines: Implications for regulatory approval by the animal rule
    • Sullivan, N.J.; Martin, J.E.; Graham, B.S.; Nabel, G.J. Correlates of protective immunity for Ebola vaccines: Implications for regulatory approval by the animal rule. Nat. Rev. Microbiol. 2009, 7, 393-400.
    • (2009) Nat. Rev. Microbiol , vol.7 , pp. 393-400
    • Sullivan, N.J.1    Martin, J.E.2    Graham, B.S.3    Nabel, G.J.4
  • 82
    • 33646135089 scopus 로고    scopus 로고
    • Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: An efficacy assessment
    • Daddario-DiCaprio, K.M.; Geisbert, T.W.; Stroher, U.; Geisbert, J.B.; Grolla, A.; Fritz, E.A.; Fernando, L.; Kagan, E.; Jahrling, P.B.; Hensley, L.E., et al. Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: An efficacy assessment. Lancet 2006, 367, 1399-1404.
    • (2006) Lancet , vol.367 , pp. 1399-1404
    • Daddario-Caprio, K.M.1    Geisbert, T.W.2    Stroher, U.3    Geisbert, J.B.4    Grolla, A.5    Fritz, E.A.6    Fernando, L.7    Kagan, E.8    Jahrling, P.B.9    Hensley, L.E.10
  • 84
    • 67650383786 scopus 로고    scopus 로고
    • Single-injection vaccine protects nonhuman primates against infection with marburg virus and three species of ebola virus
    • Geisbert, T.W.; Geisbert, J.B.; Leung, A.; Daddario-DiCaprio, K.M.; Hensley, L.E.; Grolla, A.; Feldmann, H. Single-injection vaccine protects nonhuman primates against infection with marburg virus and three species of ebola virus. J. Virol. 2009, 83, 7296-7304.
    • (2009) J. Virol , vol.83 , pp. 7296-7304
    • Geisbert, T.W.1    Geisbert, J.B.2    Leung, A.3    Daddario-Dicaprio, K.M.4    Hensley, L.E.5    Grolla, A.6    Feldmann, H.7
  • 87
    • 22144488793 scopus 로고    scopus 로고
    • Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection
    • Warfield, K.L.; Olinger, G.; Deal, E.M.; Swenson, D.L.; Bailey, M.; Negley, D.L.; Hart, M.K.; Bavari, S. Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection. J. Immunol. 2005, 175, 1184-1191.
    • (2005) J. Immunol , vol.175 , pp. 1184-1191
    • Warfield, K.L.1    Olinger, G.2    Deal, E.M.3    Swenson, D.L.4    Bailey, M.5    Negley, D.L.6    Hart, M.K.7    Bavari, S.8
  • 88
    • 0033062193 scopus 로고    scopus 로고
    • Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients
    • International Scientific and Technical Committee
    • Mupapa, K.; Massamba, M.; Kibadi, K.; Kuvula, K.; Bwaka, A.; Kipasa, M.; Colebunders, R.; Muyembe-Tamfum, J.J. Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients. International Scientific and Technical Committee. J. Infect. Dis. 1999, 179, S18-S23.
    • (1999) J. Infect. Dis , vol.179
    • Mupapa, K.1    Massamba, M.2    Kibadi, K.3    Kuvula, K.4    Bwaka, A.5    Kipasa, M.6    Colebunders, R.7    Muyembe-Tamfum, J.J.8
  • 90
    • 0035423215 scopus 로고    scopus 로고
    • Vaccine potential of Ebola virus VP24, VP30, VP35, and VP40 proteins
    • Wilson, J.A.; Bray, M.; Bakken, R.; Hart, M.K. Vaccine potential of Ebola virus VP24, VP30, VP35, and VP40 proteins. Virology 2001, 286, 384-390.
    • (2001) Virology , vol.286 , pp. 384-390
    • Wilson, J.A.1    Bray, M.2    Bakken, R.3    Hart, M.K.4
  • 92
    • 33845584363 scopus 로고    scopus 로고
    • Protective efficacy of neutralizing antibodies against Ebola virus infection
    • Takada, A.; Ebihara, H.; Jones, S.; Feldmann, H.; Kawaoka, Y. Protective efficacy of neutralizing antibodies against Ebola virus infection. Vaccine 2007, 25, 993-999.
    • (2007) Vaccine , vol.25 , pp. 993-999
    • Takada, A.1    Ebihara, H.2    Jones, S.3    Feldmann, H.4    Kawaoka, Y.5
  • 93
    • 0036100307 scopus 로고    scopus 로고
    • Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody
    • Parren, P.W.; Geisbert, T.W.; Maruyama, T.; Jahrling, P.B.; Burton, D.R. Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody. J. Virol. 2002, 76, 6408-6412.
    • (2002) J. Virol , vol.76 , pp. 6408-6412
    • Parren, P.W.1    Geisbert, T.W.2    Maruyama, T.3    Jahrling, P.B.4    Burton, D.R.5
  • 95
    • 0141568802 scopus 로고    scopus 로고
    • Characterization of monoclonal antibodies to Marburg virus (strain Musoke) glycoprotein and identification of two protective epitopes
    • Hevey, M.; Negley, D.; Schmaljohn, A. Characterization of monoclonal antibodies to Marburg virus (strain Musoke) glycoprotein and identification of two protective epitopes. Virology 2003, 314, 350-357.
    • (2003) Virology , vol.314 , pp. 350-357
    • Hevey, M.1    Negley, D.2    Schmaljohn, A.3
  • 96
    • 0035228196 scopus 로고    scopus 로고
    • Detection of antiviral activity of monoclonal antibodies, specific to Marburg virus proteins
    • Razumov, I.A.; Belanov, E.F.; Bormotov, N.I.; Kazachinskaia, E.I. Detection of antiviral activity of monoclonal antibodies, specific to Marburg virus proteins. Vopr. Virusol. 2001, 46, 33-37.
    • (2001) Vopr. Virusol , vol.46 , pp. 33-37
    • Razumov, I.A.1    Belanov, E.F.2    Bormotov, N.I.3    Kazachinskaia, E.I.4
  • 97
  • 98
    • 0035040194 scopus 로고    scopus 로고
    • Passive transfer of antibodies protects immunocompetent and imunodeficient mice against lethal Ebola virus infection without complete inhibition of viral replication
    • Gupta, M.; Mahanty, S.; Bray, M.; Ahmed, R.; Rollin, P.E. Passive transfer of antibodies protects immunocompetent and imunodeficient mice against lethal Ebola virus infection without complete inhibition of viral replication. J. Virol. 2001, 75, 4649-4654.
    • (2001) J. Virol , vol.75 , pp. 4649-4654
    • Gupta, M.1    Mahanty, S.2    Bray, M.3    Ahmed, R.4    Rollin, P.E.5
  • 103
  • 105
    • 27644432120 scopus 로고    scopus 로고
    • Protective cytotoxic T-cell responses induced by venezuelan equine encephalitis virus replicons expressing Ebola virus proteins
    • Olinger, G.G.; Bailey, M.A.; Dye, J.M.; Bakken, R.; Kuehne, A.; Kondig, J.; Wilson, J.; Hogan, R.J.; Hart, M.K. Protective cytotoxic T-cell responses induced by venezuelan equine encephalitis virus replicons expressing Ebola virus proteins. J. Virol. 2005, 79, 14189-14196.
    • (2005) J. Virol , vol.79 , pp. 14189-14196
    • Olinger, G.G.1    Bailey, M.A.2    Dye, J.M.3    Bakken, R.4    Kuehne, A.5    Kondig, J.6    Wilson, J.7    Hogan, R.J.8    Hart, M.K.9
  • 106
    • 70349337161 scopus 로고    scopus 로고
    • Discovery of common marburgvirus protective epitopes in a BALB/c mouse model
    • Kalina, W.V.; Warfield, K.L.; Olinger, G.G.; Bavari, S. Discovery of common marburgvirus protective epitopes in a BALB/c mouse model. Virol. J. 2009, 6, 132.
    • (2009) Virol. J , vol.6 , pp. 132
    • Kalina, W.V.1    Warfield, K.L.2    Olinger, G.G.3    Bavari, S.4
  • 111
    • 78649237330 scopus 로고    scopus 로고
    • Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection
    • Wauquier, N.; Padilla, C.; Becquart, P.; Leroy, E.; Vieillard, V. Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection. Immunogenetics 2010, 62, 767-771.
    • (2010) Immunogenetics , vol.62 , pp. 767-771
    • Wauquier, N.1    Padilla, C.2    Becquart, P.3    Leroy, E.4    Vieillard, V.5
  • 112
    • 38449103506 scopus 로고    scopus 로고
    • Sequence-based human leukocyte antigen-B typing of patients infected with Ebola virus in Uganda in 2000: Identification of alleles associated with fatal and nonfatal disease outcomes
    • Sanchez, A.; Wagoner, K.E.; Rollin, P.E. Sequence-based human leukocyte antigen-B typing of patients infected with Ebola virus in Uganda in 2000: Identification of alleles associated with fatal and nonfatal disease outcomes. J. Infect. Dis. 2007, 196, S329-S336.
    • (2007) J. Infect. Dis , vol.196
    • Sanchez, A.1    Wagoner, K.E.2    Rollin, P.E.3
  • 113
    • 0036149558 scopus 로고    scopus 로고
    • Viral replication and host gene expression in alveolar macrophages infected with Ebola virus (Zaire strain)
    • Gibb, T.R.; Norwood, D.A., Jr.; Woollen, N.; Henchal, E.A. Viral replication and host gene expression in alveolar macrophages infected with Ebola virus (Zaire strain). Clin. Diagn. Lab. Immunol. 2002, 9, 19-27.
    • (2002) Clin. Diagn. Lab. Immunol , vol.9 , pp. 19-27
    • Gibb, T.R.1    Norwood Jr., D.A.2    Woollen, N.3    Henchal, E.A.4
  • 115
    • 0033000979 scopus 로고    scopus 로고
    • Histopathological and immunohistochemical studies of lesions associated with Ebola virus in a naturally infected chimpanzee
    • Wyers, M.; Formenty, P.; Cherel, Y.; Guigand, L.; Fernandez, B.; Boesch, C.; Le Guenno, B. Histopathological and immunohistochemical studies of lesions associated with Ebola virus in a naturally infected chimpanzee. J. Infect. Dis. 1999, 179, S54-S59.
    • (1999) J. Infect. Dis , vol.179
    • Wyers, M.1    Formenty, P.2    Cherel, Y.3    Guigand, L.4    Fernandez, B.5    Boesch, C.6    Le, G.B.7
  • 116
    • 0033037010 scopus 로고    scopus 로고
    • An analysis of features of pathogenesis in two animal models of Ebola virus infection
    • Ryabchikova, E.I.; Kolesnikova, L.V.; Luchko, S.V. An analysis of features of pathogenesis in two animal models of Ebola virus infection. J. Infect. Dis. 1999, 179, S199-202.
    • (1999) J. Infect. Dis , vol.179
    • Ryabchikova, E.I.1    Kolesnikova, L.V.2    Luchko, S.V.3
  • 117
    • 0026559278 scopus 로고
    • Association of Ebola-related Reston virus particles and antigen with tissue lesions of monkeys imported to the United States
    • Geisbert, T.W.; Jahrling, P.B.; Hanes, M.A.; Zack, P.M. Association of Ebola-related Reston virus particles and antigen with tissue lesions of monkeys imported to the United States. J. Comp. Pathol. 1992, 106, 137-152.
    • (1992) J. Comp. Pathol , vol.106 , pp. 137-152
    • Geisbert, T.W.1    Jahrling, P.B.2    Hanes, M.A.3    Zack, P.M.4
  • 119
    • 0031915281 scopus 로고    scopus 로고
    • Marburg hemorrhagic fever: Report of a case studied by immunohistochemistry and electron microscopy
    • Geisbert, T.W.; Jaax, N.K. Marburg hemorrhagic fever: Report of a case studied by immunohistochemistry and electron microscopy. Ultrastruct. Pathol. 1998, 22, 3-17.
    • (1998) Ultrastruct. Pathol , vol.22 , pp. 3-17
    • Geisbert, T.W.1    Jaax, N.K.2
  • 120
    • 0347122085 scopus 로고    scopus 로고
    • Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation
    • Bosio, C.M.; Aman, M.J.; Grogan, C.; Hogan, R.; Ruthel, G.; Negley, D.; Mohamadzadeh, M.; Bavari, S.; Schmaljohn, A. Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation. J. Infect. Dis. 2003, 188, 1630-1638.
    • (2003) J. Infect. Dis , vol.188 , pp. 1630-1638
    • Bosio, C.M.1    Aman, M.J.2    Grogan, C.3    Hogan, R.4    Ruthel, G.5    Negley, D.6    Mohamadzadeh, M.7    Bavari, S.8    Schmaljohn, A.9
  • 121
    • 0037443448 scopus 로고    scopus 로고
    • Cutting edge: Impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses
    • Mahanty, S.; Hutchinson, K.; Agarwal, S.; McRae, M.; Rollin, P.E.; Pulendran, B. Cutting edge: Impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses. J. Immunol. 2003, 170, 2797-2801.
    • (2003) J. Immunol , vol.170 , pp. 2797-2801
    • Mahanty, S.1    Hutchinson, K.2    Agarwal, S.3    McRae, M.4    Rollin, P.E.5    Pulendran, B.6
  • 122
    • 80054775061 scopus 로고    scopus 로고
    • Ebola virus failure to stimulate plasmacytoid dendritic cell interferon responses correlates with impaired cellular entry
    • Dis. 2011, in press
    • Leung, L.W.M.O.; Reynard, O.; Volchkov, V.E.; Basler, C. Ebola virus failure to stimulate plasmacytoid dendritic cell interferon responses correlates with impaired cellular entry. J. Infect. Dis. 2011, in press.
    • J. Infect
    • Leung, L.W.M.O.1    Reynard, O.2    Volchkov, V.E.3    Basler, C.4
  • 123
    • 19344366513 scopus 로고    scopus 로고
    • Ebola virus: The role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever
    • Bray, M.; Geisbert, T.W. Ebola virus: The role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever. Int. J. Biochem. Cell Biol. 2005, 37, 1560-1566.
    • (2005) Int. J. Biochem. Cell Biol , vol.37 , pp. 1560-1566
    • Bray, M.1    Geisbert, T.W.2


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