Diagnosis and management of alcoholic liver disease

Journal of Digestive Diseases

Volumn 12, Issue 4, 2011, Pages 257-262

  McCullough, Arthur J ^a   O'Shea, Robert S ^a   Dasarathy, Srinivasan ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Alcohol; Pentoxifylline; Prognosis; Therapy cortico steroids; Transplantation

Indexed keywords

ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; AMLODIPINE; BILIRUBIN; BLOOD CLOTTING FACTOR 5; C REACTIVE PROTEIN; COLCHICINE; CORTICOSTEROID; CREATININE; CYANOCOBALAMIN; ENDOTOXIN; ETANERCEPT; GLUCAGON; HEMOGLOBIN; INFLIXIMAB; INSULIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; KETONE BODY; LIPOPOLYSACCHARIDE BINDING PROTEIN; OXANDROLONE; PENTOXIFYLLINE; PREDNISOLONE; PREDNISONE; PROPYLTHIOURACIL; SILYMARIN; TESTOSTERONE; TUMOR NECROSIS FACTOR; UNINDEXED DRUG;

AGE; AGE BILIRUBIN INR CREATININE SCORE; ALCOHOL ABSTINENCE; ALCOHOL CONSUMPTION; ALCOHOL LIVER DISEASE; BECLERE MODEL; BRAIN DISEASE; CHILD TURCOTTE PUGH SCORE; COMBINATION CHEMOTHERAPY; COMBINED CLINICAL LABORATORY INDEX OF THE UNIVERSITY OF TORONTO; CORTICOSTEROID THERAPY; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG DOSE REDUCTION; END STAGE LIVER DISEASE; ETHNICITY; FATTY LIVER; GENDER; GLASGOW ALCOHOLIC HEPATITIS SCORE; HEMOGLOBIN BLOOD LEVEL; HEPATITIS; HEPATITIS C; HISPANIC; HUMAN; KIDNEY FAILURE; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER INJURY; LIVER TRANSPLANTATION; MADDREY DISCRIMINANT FUNCTION; MODEL FOR END STAGE LIVER DISEASE; MORTALITY; NUTRITIONAL DEFICIENCY; OBESITY; PRIORITY JOURNAL; PROGNOSIS; PROTHROMBIN TIME; REVIEW; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; STEROID THERAPY; VITAMIN BLOOD LEVEL;

ADRENAL CORTEX HORMONES; HEPATITIS, ALCOHOLIC; HUMANS; LIVER DISEASES, ALCOHOLIC; LIVER TRANSPLANTATION; PENTOXIFYLLINE; TREATMENT OUTCOME;

EID: 79960743999     PISSN: 17512972     EISSN: 17512980     Source Type: Journal    
DOI: 10.1111/j.1751-2980.2010.00470.x     Document Type: Review

References (13)

1. O'Shea RS, Dasarathy S, McCullough AJ. Alcoholic liver disease. AASLD practice guidelines. Hepatology 2010; 51: 307-28.
2. Lucey MR, Brown KA, Everson GT, Fung JJ, Gish R, Keefe EB. Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases. Transplantation 1998; 66: 956-62.
3. O'Shea RS, McCullough AJ. Treatment of alcoholic hepatitis. Clin Liver Dis 2005; 9: 103-34.
4. Mathurin P, Ducharelle V, Ramond MJ etal. Survival and prognostic factor I patients with severe alcoholic hepatitis treated with prednisolone. Gastroenterology 1996; 110: 1847-53.
5. Mathurin P, Abdelnour M, Ramond MJ etal. Early change in bilirubin levels as an important prognostic factor in severe alcoholic hepatitis treated with prednisolone. Hepatology 2003; 33: 1363-9.
6. Srikurejp W, Kyola NL, Runyon R, Hu KQ. MELD score is a better prognostic model than Child-Turcotte-Pugh score or discriminant function score in patients with alcoholic hepatitis. J Hepatol 2005; 42: 700-6.
7. Mathurin P, Mendenhall CL, Caritheres RL, Maddrey WC, Garstide P. Corticosteroids improve short term survival in patients with severe alcoholic hepatitis (AH): individual data analysis of the last three randomized placebo controlled double blind trials of corticosteroids in severe AH. J Hepatol 2002; 36: 480-7.
8. Mendenhall C, Roselle GA, Garstide P Moritz T. Relationship of protein caloric malnutrition to alcoholic liver disease: a reexamination of data from two Veterans Administration Cooperative Studies. Alcohol Clin Exp Res 1995; 19: 636-41.
9. Cabre E, Ridruguez-Iglesias P, Caballeria J, Querr JC, Sanchez-Lombrana JL, Pares A. Short and long term outcome of severe alcohol hepatitis treated with steroids or enteral nutrition: a multicenter randomized trial. Hepatology 2000; l32: 36-42.
10. Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. Pentoxifylline improves short term survival in severe acute alcoholic hepatitis: a double blind placebo controlled trial. Gastroenterology 2000; 119: 1637-48.
11. Louvet A, Diaz E, Dharancy S, Coevoet H etal. Early switch to pentoxifylline in patients with severe alcoholic hepatitis is inefficient in non-responders to corticosteroids. J Hepatol 2008; 48: 465-70.
12. Perney P, Bismuth M, Siguare H, Picot MC, Jacquet E, Puche P. Are preoperative patterns of alcohol consumption predictive of relapse after liver transplantation for alcoholic liver disease? Transpl Int 2005; 18: 1292-7.
13. Mathurin P. Is alcoholic hepatitis an indication for transplantation? Liver Transpl 2005; 11: S21-24.