Pharmacologic reversal of epigenetic silencing of the anticancer protein BRM: A novel targeted treatment strategy

Oncogene

Volumn 30, Issue 29, 2011, Pages 3289-3294

  Gramling, S ^a   Rogers, C ^a   Liu, G ^b   Reisman, D ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

cancer therapy; chromatin remodeling; epigenetic; SWI SNF; target therapy; tumor suppressor

Indexed keywords

ANTINEOPLASTIC AGENT; BRM PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GK 0037; PROTEIN SWI; RH 02032; TRANSCRIPTION FACTOR SNF; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; GENE MUTATION; GENE SILENCING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN TISSUE; ONCOGENE; PRIORITY JOURNAL; SOLID TUMOR; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE;

CELL DIVISION; EPIGENESIS, GENETIC; GENE SILENCING; HUMANS; NEOPLASMS; POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

EID: 79960740365     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.80     Document Type: Article

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