Clinical effectiveness and cost benefit of universal versus targeted methicillin-resistant Staphylococcus aureus screening upon admission in hospitals

Infection Control and Hospital Epidemiology

Volumn 32, Issue 8, 2011, Pages 797-803

  Leonhardt, Kathryn K ^a   Yakusheva, Olga ^b   Phelan, David ^a   Reeths, Anne ^a   Hosterman, Teresa ^a   Bonin, Deborah ^a   Costello, Mike ^a  

^a AURORA HEALTH CARE   (United States)

^b MARQUETTE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; COST BENEFIT ANALYSIS; FEMALE; HEALTH CARE COST; HOSPITAL ADMISSION; HOSPITAL BASED CASE CONTROL STUDY; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INFECTION RATE; INTERMETHOD COMPARISON; INTERVENTION STUDY; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDY; SCREENING TEST;

ADULT; CASE-CONTROL STUDIES; COST-BENEFIT ANALYSIS; CROSS INFECTION; FEMALE; HUMANS; INFECTION CONTROL; MALE; MASS SCREENING; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PATIENT ADMISSION; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; STAPHYLOCOCCAL INFECTIONS; WISCONSIN;

EID: 79960727325     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/660875     Document Type: Article

References (21)

1. Cosgrove SE, Qi Y, Kaye KS, Harbarth S, Karchmer AW, Carmeli Y. The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Infect Control Hosp Epidemiol 2005;26:166-174.
2. Peterson LR, Hacek DM, Robicsek A. Case study: an MRSA intervention at Evanston Northwestern Healthcare. Jt Comm J Qual Patient Saf 2007;33(12):732-738.
3. Harbarth S, Fankhauser C, Schrenzel J, et al. Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients. JAMA 2008;299(10):1149-1157.
4. Robicsek A, Beaumont JL, Paule SM, et al. Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals. Ann Intern Med 2008;148(6):409-418.
5. Peterson LR, Diekema DJ. To screen or not to screen for MRSA. J Clin Microbiol 2010;48(3):683-689.
6. Rodriguez-Bano J, Garcia L, Ramirez E, et al. Long-term control of endemic hospital-wide methicillin-resistant Staphylococcus aureus (MRSA): the impact of targeted active surveillance for MRSA in patients and healthcare workers. Infect Control Hosp Epidemiol 2010;31(8):786-795.
7. Tacconelli E, De Angelis G, de Waure C, Cataldo M, La Torre G, Cauda R. Rapid screening tests for methicillin-resistant Staphylococcus aureus at hospital admission: systematic review and meta-analysis. Lancet Infect Dis 2009;9:546-554.
8. McGinigle K, Gourlay M, Buchanan I. The use of active surveillance cultures in adult intensive care units to reduce methicillin- resistant Staphylococcus aureus-related morbidity, mortality, and costs: a systematic review. Clin Infect Dis 2008;46: 1717-1725.
9. CDC. The National Healthcare Safety Network (NHSN) Manual, Patient Safety Component. Protocol multidrug-resistant organisms. December 2008. http://www.cdc.gov/ncidod/dhqp/pdf/nhsn/MDRO_CDADprotocolv41Dec08final.pdf. Accessed March 15, 2009.
10. Folland S, Goodman AC, Stano M. The Economics of Health and Health Care. 6th ed. Upper Saddle River, NJ: Pearson Education; 2010.
11. Murray MP. Econometrics: A Modern Introduction. Boston: Pearson Education; 2006.
12. Chaix C, Durand-Zaleski I, Alberti C, Brun-Buisson C. Control of endemic methicillin-resistant Staphylococcus aureus: a costbenefit analysis in an intensive care unit. JAMA 1999;282: 1745-1751.
13. Hardy K, Price C, Szczepura A, et al. Reduction in the rate of methicillin-resistant Staphylococcus aureus acquisition in surgical wards by rapid screening for colonization: a prospective, crossover study. Clin Microbiol Infect 2010;16(4):333-339.
14. Harbarth S, Masuet-Aumatell C, Schrenzel J, et al. Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study. Crit Care 2006;10:R25.
15. Jeyaratnam D, Whitty CJ, Phillips K, et al. Impact of rapid screening tests on acquisition of methicillin resistant Staphylococcus aureus: cluster randomised crossover trial. BMJ 2008; 336(7650):927-930.
16. Engemann JJ, Carmeli Y, Cosgrove SE, et al. Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection. Clin Infect Dis 2003;36:592-598.
17. Anderson DJ, Kaye KS, Chen LF, et al. Clinical and financial outcomes due to methicillin resistant Staphylococcus aureus surgical site infection: a multi-center matched outcomes study. PLoS ONE 2009;4(12):e8305.
18. Larcombe L, Waruk J, Schellenberg J, Ormond M. Rapid emergence of methicillin-resistant Staphylococcus aureus (MRSA) among children and adolescents in northern Manitoba, 2003-2006. Can Commun Dis Rep 2007;33(2):9-14.
19. Kallen AJ, Mu Y, Bulens S, et al. Health care-associated invasive MRSA infections, 2005-2008. JAMA 2010;304(6):641-648.
20. Cohen AL, Calfee D, Fridkin SK, et al. Recommendations for metrics for multidrug-resistant organisms in healthcare settings: SHEA/HICPAC position paper. Infect Control Hosp Epidemiol 2008;29(10):901-913.
21. Huang SS, Platt R. Risk of methicillin-resistant Staphylococcus aureus infection after previous infection or colonization. Clin Infect Dis 2003;36:281-285.