The influence of comorbidities on overall survival among older women diagnosed with breast cancer

Journal of the National Cancer Institute

Volumn 103, Issue 14, 2011, Pages 1101-1111

  Patnaik, Jennifer L ^a   Byers, Tim ^a   Diguiseppi, Carolyn ^a   Denberg, Thomas D ^b   Dabelea, Dana ^a  

^a Department of Civil and Environmental Engineering at Colorado State University and the Department of Environmental and Occupational Health at the Colorado School of Public Health   (United States)

^b HARVARD VANGUARD MEDICAL ASSOCIATES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR MARKER;

AGED; ARTICLE; BREAST CANCER; CANCER MORTALITY; CANCER REGISTRY; CANCER STAGING; CANCER SURVIVAL; CEREBROVASCULAR DISEASE; CHRONIC KIDNEY FAILURE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMORBIDITY; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DATA BASE; DEMENTIA; DIABETES MELLITUS; DISEASE ASSOCIATION; ETHNICITY; FEMALE; HAZARD RATIO; HEART INFARCTION; HOSPITAL PATIENT; HUMAN; KAPLAN MEIER METHOD; LIVER DISEASE; MAJOR CLINICAL STUDY; OUTPATIENT CARE; OVERALL SURVIVAL; PARALYSIS; PERIPHERAL VASCULAR DISEASE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RACE; RHEUMATOID ARTHRITIS; STOMACH ULCER;

AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; COMORBIDITY; CONFOUNDING FACTORS (EPIDEMIOLOGY); DATABASES, FACTUAL; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MEDICARE; MORTALITY; ODDS RATIO; PREDICTIVE VALUE OF TESTS; PREVALENCE; PROPORTIONAL HAZARDS MODELS; RISK ASSESSMENT; RISK FACTORS; SEER PROGRAM; UNITED STATES;

EID: 79960723969     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djr188     Document Type: Article

References (49)

1. Horner MJ, Ries LAG, Krapcho M, et al. SEER Cancer Statistics Review, 1975-2006; Bethesda, MD: National Cancer Institute; 2009 http://seer.cancer.gov/ csr/1975-2006/. Accessed May 16, 2011.
2. Lewis JH, Kilgore ML, Goldman DP, et al. Participation of patient 65 years of age or older in cancer clinical trials. J Clin Oncol. 2003;21(7):1383-1389. (Pubitemid 46606420)
3. Trimble EL, Carter CL, Cain D, Freidlin B, Ungerleider RS, Friedman MA. Representation of older patients in cancer treatment trials. Cancer. 1994;74(7):2208-2214. (Pubitemid 24304400)
4. Hutchins LF, Unger JM, Crowley JJ, Coltman CA, Albain KS. Underrepresentation of patients 65 years of age or older in cancer treatment trials. N Engl J Med. 1999;341(27):2061-2067. (Pubitemid 30035956)
5. Murthy VH, Krumholz HM, Gross CP. Participation in cancer clinical trials, race, sex and age-based disparities. JAMA. 2004;291(22):2720-2726. (Pubitemid 38725421)
6. Unger JM, Coltman CA, Crowley JJ, et al. Impact of the year 2000 Medicare policy change on older patient enrollment to cancer clinical trials. J Clin Oncol. 2006;24(1):141-144. (Pubitemid 46630505)
7. Guralnik JM. Assessing the impact of comorbidity in older populations. Ann Epidemiol. 1996;6(5):376-380. (Pubitemid 26372525)
8. Yancik R. Cancer burden in the aged: an epidemiologic and demographic overview. Cancer. 1997;80(7):1273-1283. (Pubitemid 27407230)
9. Ogle KS, Swanson GM, Woods N, Azzouz F. Cancer and comorbidity: redefining chronic diseases. Cancer. 2000;88(3):653-663. (Pubitemid 30056943)
10. Klabunde CN, Warren JL, Legler JM. Assessing comorbidity using claims data: an overview. Med Care. 2002;40(suppl 8):IV26-IV35.
11. Yancik R, Wesley MN, Ries LAG, Havlik RJ, Edwards BK, Yates JW. Effect of age and comorbidity in postmenopausal breast cancer patients aged 55 years and older. JAMA. 2001;285(7):885-892. (Pubitemid 32171549)
12. Louwman WJ, Janssen-Heijnen MLG, Houterman S, et al. Less extensive treatment and inferior prognosis for breast cancer patients with comorbidity: a population-based study. Eur J Cancer. 2005;41(5):779-785. (Pubitemid 40347298)
13. Satariano WA, Ragland DR. The effect of comorbidity on 3-year survival of women with primary breast cancer. Ann Intern Med. 1994;120(2):104-110. (Pubitemid 24027550)
14. Houterman S, Janssen-Heijnen MLG, Verheij CD, et al. Comorbidity has negligible impact on treatment and complications but influences survival in breast cancer patients. Br J Cancer. 2004;90(12):2232-2237.
15. Nagel G, Wedding U, Hoyer H, Rohrig B, Katenkamp D. The impact of comorbidity on the survival of postmenopausal women with breast cancer. J Cancer Res Clin Oncol. 2004;130(11):664-670. (Pubitemid 39506380)
16. Cronin-Fenton DP, Norgaard M, Jacobsen J, et al. Comorbidity and survival of Danish breast cancer patients from 1995 to 2005. Brit J Cancer. 2007;96(9):1462-1468. (Pubitemid 46685783)
17. Janssen-Heijnen MLG, Maas HAAM, Houterman S, Lemmens VE, Rutten HJ, Coebergh JW. Comorbidity in older surgical cancer patients: influence on patient care and outcome. Eur J Cancer. 2007;43(15):2179-2193. (Pubitemid 47539116)
18. West DW, Satariano WA, Ragland DR, Hiatt RA. Comorbidity and breast cancer survival: a comparison between black and white women. Ann Epidemiol. 1996;6(5):413-419. (Pubitemid 26372529)
19. US Public Health Service. International Classification of Diseases, 9th Revision. Washington, DC: US GPO; 1996.
20. American Medical Association. Physicians' Current Procedural Terminology. CPT 95. 5th ed. Chicago, IL: American Medical Association; 1994.
21. Warren JL, Klabunde CN, Schrag D, Bach PB, Riley GF. Overview of the SEER-Medicare data: content, research applications, and generalizability to the United States elderly population. Med Care. 2002;40(8 suppl):3-18.
22. Potosky AL, Riley GF, Lubitz JD, Mentnech RM, Kessler LG. Potential for cancer related health services research using a linked Medicare-tumor registry database. Med Care. 1993;31(8):732-748.
23. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis. 1987;40(5):373-383. (Pubitemid 17055592)
24. Charlson ME, Szatrowski TP, Peterson J, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994;47(11):1245-1251. (Pubitemid 24361532)
25. Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45(6):613-619.
26. Klabunde CN, Potosky AL, Legler JM, Warren JL. Development of a comorbidity index using physician claims data. J Clin Epidemiol. 2000;53(12):1258-1267. (Pubitemid 32007842)
27. Newschaffer CJ, Bush TL, Penberthy LT. Comorbidity measurement in elderly female breast cancer patients with administrative and medical records data. J Clin Epidemiol. 1997;50(6):725-733. (Pubitemid 27341823)
28. National Cancer Institute. SEER-Medicare Database. Bethesda, MD: National Cancer Institute. http://healthservices.cancer.gov/seermedicare/. Accessed December 7, 2009.
29. Du Xl, Key CR, Dickie L, Darling R, Geraci JM, Zhang D. External validation of Medicare claims for breast cancer chemotherapy compared with medical chart reviews. Med Care. 2006;44(2):124-131. (Pubitemid 43755463)
30. Smith Gl, Smith BD, Giordano SH, et al. Risk of hypothyroidism in older breast cancer patients treated with radiation. Cancer. 2008;112(6):1371-1379. (Pubitemid 351429753)
31. Warren Jl, Harlan LC, Fahey A, et al. Utility of the SEER-Medicare data to identify chemotherapy use. Med Care. 2002;40(suppl 8):IV-55-IV-61.
32. Srokowski TP, Fang S, Duan Z, et al. Completion of adjuvant radiation therapy among women with breast cancer. Cancer. 2008;113(1):22-29. (Pubitemid 351976382)
33. Virnig BA, Warren JL, Cooper GS, Klabunde CN, Schussler N, Freeman J. Studying radiation therapy using SEER-Medicare linked data. Med Care. 2002;40(suppl 8):IV49-IV54.
34. Katki HA, Mark S. Survival analysis for cohorts with missing covariate information. R News. 2008;8(1):14-19.
35. Fleming ST, Rastogi A, Dmitrienko A, Johnson KD. A comprehensive prognostic index to predict survival based on multiple comorbidities: a focus on breast cancer. Med Care. 1999;37(6):601-614.
36. Elixhauser A, Claudia S, Harris RD, Coffey RM. Comorbidity measures for use with administrative data. Med Care. 1998;36(1):8-27. (Pubitemid 128456396)
37. Extermann M. Measuring comorbidity in older cancer patients. Eur J Cancer. 2000;36(4):453-471. (Pubitemid 30136223)
38. Havlik RJ, Yancik R, Long S, Ries L, Edwards B. The National Institute on Aging and the National Cancer Institute SEER collaborative study on comorbidity and early diagnosis of cancer in the elderly. Cancer. 1994;74(7):2101-2106. (Pubitemid 24304381)
39. Kahi CJ, Azzouz F, Juliar BE, Imperiale TF. Survival of elderly persons undergoing colonoscopy: implications for colorectal cancer screening and surveillance. Gastrointest Endosc. 2007;66(3):544-550. (Pubitemid 47304413)
40. Alho OP, Hannula K, Luokkala A, Teppo H, Koivunen P, Kantola S. Differential prognostic impact of comorbidity in head and neck cancer. Head Neck. 2007;29(10):913-918.
41. Post PN, Hansen BE, Kil PJ, Janssen-Heijnen ML, Coebergh JW. The independent prognostic value of comorbidity among men aged 〈 75 with localized prostate cancer: a population-based study. BJU Int. 2001;87(9):821-826. (Pubitemid 34204322)
42. Froehner M, Koch R, Litz RJ, Hakenberg OW, Oehlschlaeger S, Wirth MP. Interaction between age and comorbidity as predictors of mortality after radical prostatectomy. J Urol. 2008;179(5):1823-1829.
43. Gross CP, Guo Z, McAvay GJ, Allore HG, Young M, Tinetti ME. Multimorbidity and survival in older persons with colorectal cancer. J Am Geriatr Soc. 2006;54(12):1898-1904. (Pubitemid 44915834)
44. Klabunde CN, Harlan LC, Warren JL. Data sources for measuring comorbidity: a comparison of hospital records and Medicare claims for cancer patients. Med Care. 2006;44(10):921-928. (Pubitemid 44454569)
45. Kirsner RS, Ma F, Fleming L, et al. The effect of Medicare health care delivery systems on survival for patients with breast and colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2006;15(4):769-773.
46. Du X, Goodwin JS. Patterns of use of chemotherapy for breast cancer in older women: findings from Medicare claims data. J Clin Oncol. 2001;19(5):1455-1461. (Pubitemid 32202553)
47. Baxter NN, Durham SB, Phillips KA, Habermann EB, Virning BA. Risk of dementia in older breast cancer survivors: a population-based cohort study of the association with adjuvant chemotherapy. J Am Geriatrics Soc. 2009;57(3):403-411.
48. Kirkpatrick HM, Aitelli CL, Qin H, et al. Referral patterns and adjuvant chemotherapy use in patients with stage II colon cancer. Clin Colorectal Cancer. 2010;9(3):150-156.
49. DeMichele A, Putt M, Zhang Y, Glick JH, Norman S. Older age predicts a decline in adjuvant chemotherapy recomendations for patients with breast carcinoma. Cancer. 2003;97(9):2150-2159.