Evaluation of hypolipidemic and potential antioxidant effects of Pigeon pea (Cajanus cajan (l) mill sp.) leaves in alloxan-induced hyperglycemic rats

Journal of Medicinal Plants Research

Volumn 5, Issue 12, 2011, Pages 2521-2524

  Akinloye, O A ^a   Solanke, O O ^a  

^a FEDERAL UNIVERSITY OF AGRICULTURE   (Nigeria)

Author keywords

Antioxidant activity; Cajanus cajan; Hypolipidemic effect

Indexed keywords

ALANINE AMINOTRANSFERASE; ALLOXAN; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CAJANUS CAJAN EXTRACT; CREATININE; GLIBENCLAMIDE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPOLIPEMIA; IN VITRO STUDY; MALE; NONHUMAN; PIGEONPEA; PLANT LEAF; PROTEIN BLOOD LEVEL; RAT; SOLVENT EXTRACTION; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL; UREA BLOOD LEVEL;

CAJANUS CAJAN; RATTUS;

EID: 79960718676     PISSN: None     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Amarowicz R, Regg RB, Moghaddam PR, Barl BW, Neil JA (2004). A free radical scavenging capacity and antioxidant activity of selected plant species from Canadian praires. Food Chem., 84: 537-562.
2. Asham R, Islam KM, Musaddik A, Haque E (2009). Hepatoprotective activity of methanol extract of some medicinal plants against carbon tetrachloride induced hepatotoxicity in albino rats. Glob. J. Pharmacol., 3(3): 116-122.
3. Baradaran A, Nasri H (2006). Serum cholesterol as a marker of nutrition in end-stage renal failure patients on replacement therapy. Int. J. pharmacol., 2: 184-187.
4. Chakraborty SK, Kumbhar BK, Sarkar BC (2007). Process parameter optimizing for instant pigeon pea ohal using response surface methodology. J. food Eng., 81: 171-178.
5. Draper HH, Hadley M (1990). Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol., 186: 421-431.
6. El BHA (2005). Hepatoprotective effect of green tea (Camellia sinensis) extract against tamoxifen-induced liver injury in rats. J. Biochem. Mol. Biol., 38(5): 563-570.
7. Fu YJ, Zu YG, Liu W, Efferth T, Zhang NJ, Liu XN, Kong Y (2006). Optimization of luteolin separation from pigeon pea (Cajanus cajan (L) mill sp) leaves by macroporous resin. J. Chromatogr., 1137: 145-152.
8. Ghasi S, Nwobodo E, Ofili JO (2000). Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high fat diet fed wister rats. J. Ethnopharm., 69: 21-25.
9. Huang GY, Liao XE, Liao HF, Deng SJ, Tan YH, Zhon JY (2006). Studies on water soluble extracts from Cajanus cajan leaf against hypoxic-ischemic brain damage. Tradit. Chin. Drug Res. Clin. Pharmacol., 17: 172-174.
10. Kundu R, Dasgupta S, Biswas A, Bhattacharya S (2008). Cajanus cajan linn (Leguminosae) prevents alcohol-induced rat liver damage and augments cytoprotective functions. J. Ethnopharmacol., 118: 440-447.
11. Li ZH, Zhon CH, Gu Y, Zhang JY (2001). The present status of study and utilization of pigeon pea in China and its prospects. For. Res., 14: 674-681.
12. Luo QF, Sun L, Si JY, Chen DH (2008). Hypocholesterolemic effect of stilbenes containing extract-fractions from Cajanus cajan L on diet-induced hypercholesterolemia in mice. Phytomed., 15: 932-939.
13. Merina AJ, Swanesan D, Begum VH Sulochana N (2010). Antioxidant and hypolipidemic effect of Plumeria rubra L. in alloxan induced hyperglycemic rats. E-J. Chem., 7(1): 1-5.
14. Okpuzor J, Kareem G, Ejikeme C (2009). Lipid lowering activity of Globimetula braunii. Res. J. Med. Plt., 3(2): 45-51.
15. Sharma B, Satapathi SK, Roy P (2007). Hypoglycemic and hypolipidemic effects of Aegle marmelous (L) leaf extract on streptozotocin induced diabetic mice. Int. J. Pharmacol., 3: 444-452.
16. nd ed McGraw-Hill Book Co., New York.
17. Superko HR, Krauss RM (2000). Garlic powder, effect of plasma lipids, postprandial lipemia, low-density lipoprotein particle size, high-density lipoprotein subclass distribution and lipoprotein. J. Am. Coll. Cardiol., 35: 321-326.
18. Yen GC, Duh PD (1994). Scavenging effect of methanolic extract of peanut hulls on free-radicals and active oxygen species. J. Agric. Foodchem., 42: 629-632.
19. Ziaei S, Hantoshzadeh S, Rezasoltani P, Lamyian M (2001). The effects of garlic tablet on plasma lipids and platelets aggregation in nulliparous pregnants at high risk of pre-eclamsia. Eur. J. Obstet. Gynecol. Reprod. Biol., 99: 201-206.