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Volumn 6, Issue 7, 2011, Pages

Episodic therapy for genital herpes in Sub-Saharan Africa: A pooled analysis from three randomized controlled trials

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; PLACEBO; VIRUS RNA;

EID: 79960713619     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022601     Document Type: Article
Times cited : (6)

References (28)
  • 1
    • 1942531336 scopus 로고    scopus 로고
    • Epidemiology of herpes simplex virus type 2 infection in the developing world
    • Weiss H, (2004) Epidemiology of herpes simplex virus type 2 infection in the developing world. Herpes 11 (Suppl 1): 24A-35A.
    • (2004) Herpes , vol.11 , Issue.SUPPL. 1
    • Weiss, H.1
  • 2
    • 0020578052 scopus 로고
    • Genital herpes simplex virus infections: clinical manifestations, course, and complications
    • Corey L, Adams HG, Brown ZA, Holmes KK, (1983) Genital herpes simplex virus infections: clinical manifestations, course, and complications. Ann Intern Med 98: 958-972.
    • (1983) Ann Intern Med , vol.98 , pp. 958-972
    • Corey, L.1    Adams, H.G.2    Brown, Z.A.3    Holmes, K.K.4
  • 3
    • 84935315195 scopus 로고
    • Treatment of recurrent genital herpes simplex infections with oral acyclovir. A controlled trial
    • Reichman RC, Badger GJ, Mertz GJ, Corey L, Richman DD, et al. (1984) Treatment of recurrent genital herpes simplex infections with oral acyclovir. A controlled trial. JAMA 251: 2103-2107.
    • (1984) JAMA , vol.251 , pp. 2103-2107
    • Reichman, R.C.1    Badger, G.J.2    Mertz, G.J.3    Corey, L.4    Richman, D.D.5
  • 4
    • 10644248985 scopus 로고
    • Double-blind placebo-controlled trial of oral acyclovir in first-episode genital herpes simplex virus infection
    • Mertz GJ, Critchlow CW, Benedetti J, Reichman RC, Dolin R, et al. (1984) Double-blind placebo-controlled trial of oral acyclovir in first-episode genital herpes simplex virus infection. JAMA 252: 1147-1151.
    • (1984) JAMA , vol.252 , pp. 1147-1151
    • Mertz, G.J.1    Critchlow, C.W.2    Benedetti, J.3    Reichman, R.C.4    Dolin, R.5
  • 5
    • 0004111883 scopus 로고    scopus 로고
    • Organization WH, Geneva, World Health Organization, ISBN 92 4 154626 3 ISBN 92 4 154626 3
    • Organization WH (2003) Guidelines for the management of sexually transmitted infections Geneva World Health Organization ISBN 92 4 154626 3 ISBN 92 4 154626 3.
    • (2003) Guidelines for the Management of Sexually Transmitted Infections
  • 6
    • 77955173503 scopus 로고    scopus 로고
    • Genital ulcer disease treatment policies and access to acyclovir in eight sub-Saharan African countries
    • Corbell C, Stergachis A, Ndowa F, Ndase P, Barnes L, et al. (2010) Genital ulcer disease treatment policies and access to acyclovir in eight sub-Saharan African countries. Sex Transm Dis 37: 488-493.
    • (2010) Sex Transm Dis , vol.37 , pp. 488-493
    • Corbell, C.1    Stergachis, A.2    Ndowa, F.3    Ndase, P.4    Barnes, L.5
  • 7
    • 67650649763 scopus 로고    scopus 로고
    • Impact of acyclovir on genital and plasma HIV-1 RNA, genital herpes simplex virus type 2 DNA, and ulcer healing among HIV-1-infected African women with herpes ulcers: a randomized placebo-controlled trial
    • Mayaud P, Legoff J, Weiss HA, Gresenguet G, Nzambi K, et al. (2009) Impact of acyclovir on genital and plasma HIV-1 RNA, genital herpes simplex virus type 2 DNA, and ulcer healing among HIV-1-infected African women with herpes ulcers: a randomized placebo-controlled trial. J Infect Dis 200: 216-226.
    • (2009) J Infect Dis , vol.200 , pp. 216-226
    • Mayaud, P.1    Legoff, J.2    Weiss, H.A.3    Gresenguet, G.4    Nzambi, K.5
  • 8
    • 77958077166 scopus 로고    scopus 로고
    • Impact of aciclovir on ulcer healing, lesional, genital and plasma HIV-1 RNA among patients with genital ulcer disease in Malawi
    • Phiri S, Hoffman IF, Weiss HA, Martinson F, Nyirenda N, et al. (2010) Impact of aciclovir on ulcer healing, lesional, genital and plasma HIV-1 RNA among patients with genital ulcer disease in Malawi. Sex Transm Infect 86: 345-352.
    • (2010) Sex Transm Infect , vol.86 , pp. 345-352
    • Phiri, S.1    Hoffman, I.F.2    Weiss, H.A.3    Martinson, F.4    Nyirenda, N.5
  • 9
    • 70349337700 scopus 로고    scopus 로고
    • Improvement in healing and reduction in HIV shedding with episodic acyclovir therapy as part of syndromic management among men: a randomized, controlled trial
    • Paz-Bailey G, Sternberg M, Puren AJ, Markowitz LE, Ballard R, et al. (2009) Improvement in healing and reduction in HIV shedding with episodic acyclovir therapy as part of syndromic management among men: a randomized, controlled trial. J Infect Dis 200: 1039-1049.
    • (2009) J Infect Dis , vol.200 , pp. 1039-1049
    • Paz-Bailey, G.1    Sternberg, M.2    Puren, A.J.3    Markowitz, L.E.4    Ballard, R.5
  • 10
    • 77952013425 scopus 로고    scopus 로고
    • Revision of the national guideline for first-line comprehensive management and control of sexually transmitted infections: what's new and why?
    • Lewis DA, Marumo E, (2010) Revision of the national guideline for first-line comprehensive management and control of sexually transmitted infections: what's new and why? SA Fam Pract 52: 20-24.
    • (2010) SA Fam Pract , vol.52 , pp. 20-24
    • Lewis, D.A.1    Marumo, E.2
  • 11
    • 1642420994 scopus 로고    scopus 로고
    • A modified poisson regression approach to prospective studies with binary data
    • Zou G, (2004) A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol 159: 702-706.
    • (2004) Am J Epidemiol , vol.159 , pp. 702-706
    • Zou, G.1
  • 12
    • 3042667015 scopus 로고    scopus 로고
    • Genital herpes and human immunodeficiency virus: double trouble
    • Celum C, Levine R, Weaver M, Wald A, (2004) Genital herpes and human immunodeficiency virus: double trouble. Bull World Health Organ 82: 447-453.
    • (2004) Bull World Health Organ , vol.82 , pp. 447-453
    • Celum, C.1    Levine, R.2    Weaver, M.3    Wald, A.4
  • 13
    • 33847145489 scopus 로고    scopus 로고
    • Synergistic copathogens-HIV-1 and HSV-2
    • Corey L, (2007) Synergistic copathogens-HIV-1 and HSV-2. N Engl J Med 356: 854-856.
    • (2007) N Engl J Med , vol.356 , pp. 854-856
    • Corey, L.1
  • 14
    • 68649125096 scopus 로고    scopus 로고
    • Herpes simplex virus type 2: a key role in HIV incidence
    • Glynn JR, Biraro S, Weiss HA, (2009) Herpes simplex virus type 2: a key role in HIV incidence. AIDS 23: 1595-1598.
    • (2009) AIDS , vol.23 , pp. 1595-1598
    • Glynn, J.R.1    Biraro, S.2    Weiss, H.A.3
  • 15
    • 42049102191 scopus 로고    scopus 로고
    • Effect of herpes simplex suppression on incidence of HIV among women in Tanzania
    • Watson-Jones D, Weiss HA, Rusizoka M, Changalucha J, Baisley K, et al. (2008) Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. N Engl J Med 358: 1560-1571.
    • (2008) N Engl J Med , vol.358 , pp. 1560-1571
    • Watson-Jones, D.1    Weiss, H.A.2    Rusizoka, M.3    Changalucha, J.4    Baisley, K.5
  • 16
    • 45249108765 scopus 로고    scopus 로고
    • Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial
    • Celum C, Wald A, Hughes J, Sanchez J, Reid S, et al. (2008) Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial. Lancet 371: 2109-2119.
    • (2008) Lancet , vol.371 , pp. 2109-2119
    • Celum, C.1    Wald, A.2    Hughes, J.3    Sanchez, J.4    Reid, S.5
  • 17
    • 76149129743 scopus 로고    scopus 로고
    • Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2
    • Celum C, Wald A, Lingappa JR, Magaret AS, Wang RS, et al. (2010) Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2. N Engl J Med 362: 427-439.
    • (2010) N Engl J Med , vol.362 , pp. 427-439
    • Celum, C.1    Wald, A.2    Lingappa, J.R.3    Magaret, A.S.4    Wang, R.S.5
  • 18
    • 50849123514 scopus 로고    scopus 로고
    • Suppressive acyclovir therapy reduces HIV cervicovaginal shedding in HIV- and HSV-2-infected women, Chiang Rai, Thailand
    • Dunne EF, Whitehead S, Sternberg M, Thepamnuay S, Leelawiwat W, et al. (2008) Suppressive acyclovir therapy reduces HIV cervicovaginal shedding in HIV- and HSV-2-infected women, Chiang Rai, Thailand. J Acquir Immune Defic Syndr 49: 77-83.
    • (2008) J Acquir Immune Defic Syndr , vol.49 , pp. 77-83
    • Dunne, E.F.1    Whitehead, S.2    Sternberg, M.3    Thepamnuay, S.4    Leelawiwat, W.5
  • 19
    • 57149099591 scopus 로고    scopus 로고
    • A randomised placebo-controlled trial to explore the effect of suppressive therapy with acyclovir on genital shedding of HIV-1 and herpes simplex virus type 2 among Zimbabwean sex workers
    • Cowan FM, Pascoe SJ, Barlow KL, Langhaug LF, Jaffar S, et al. (2008) A randomised placebo-controlled trial to explore the effect of suppressive therapy with acyclovir on genital shedding of HIV-1 and herpes simplex virus type 2 among Zimbabwean sex workers. Sex Transm Infect 84: 548-553.
    • (2008) Sex Transm Infect , vol.84 , pp. 548-553
    • Cowan, F.M.1    Pascoe, S.J.2    Barlow, K.L.3    Langhaug, L.F.4    Jaffar, S.5
  • 20
    • 38449119047 scopus 로고    scopus 로고
    • Herpes simplex virus (HSV) suppression with valacyclovir reduces rectal and blood plasma HIV-1 levels in HIV-1/HSV-2-seropositive men: a randomized, double-blind, placebo-controlled crossover trial
    • Zuckerman RA, Lucchetti A, Whittington WL, Sanchez J, Coombs RW, et al. (2007) Herpes simplex virus (HSV) suppression with valacyclovir reduces rectal and blood plasma HIV-1 levels in HIV-1/HSV-2-seropositive men: a randomized, double-blind, placebo-controlled crossover trial. J Infect Dis 196: 1500-1508.
    • (2007) J Infect Dis , vol.196 , pp. 1500-1508
    • Zuckerman, R.A.1    Lucchetti, A.2    Whittington, W.L.3    Sanchez, J.4    Coombs, R.W.5
  • 21
    • 62349128691 scopus 로고    scopus 로고
    • HSV suppression reduces seminal HIV-1 levels in HIV-1/HSV-2 co-infected men who have sex with men
    • Zuckerman RA, Lucchetti A, Whittington WL, Sanchez J, Coombs RW, et al. (2009) HSV suppression reduces seminal HIV-1 levels in HIV-1/HSV-2 co-infected men who have sex with men. AIDS 23: 479-483.
    • (2009) AIDS , vol.23 , pp. 479-483
    • Zuckerman, R.A.1    Lucchetti, A.2    Whittington, W.L.3    Sanchez, J.4    Coombs, R.W.5
  • 22
    • 56749131188 scopus 로고    scopus 로고
    • Herpes simplex virus (HSV)-suppressive therapy decreases plasma and genital HIV-1 levels in HSV-2/HIV-1 coinfected women: a randomized, placebo-controlled, cross-over trial
    • Baeten JM, Strick LB, Lucchetti A, Whittington WL, Sanchez J, et al. (2008) Herpes simplex virus (HSV)-suppressive therapy decreases plasma and genital HIV-1 levels in HSV-2/HIV-1 coinfected women: a randomized, placebo-controlled, cross-over trial. J Infect Dis 198: 1804-1808.
    • (2008) J Infect Dis , vol.198 , pp. 1804-1808
    • Baeten, J.M.1    Strick, L.B.2    Lucchetti, A.3    Whittington, W.L.4    Sanchez, J.5
  • 23
    • 77950932091 scopus 로고    scopus 로고
    • Long-term impact of acyclovir suppressive therapy on genital and plasma HIV RNA in Tanzanian women: a randomized controlled trial
    • Tanton C, Weiss HA, Rusizoka M, Legoff J, Changalucha J, et al. (2010) Long-term impact of acyclovir suppressive therapy on genital and plasma HIV RNA in Tanzanian women: a randomized controlled trial. J Infect Dis 201: 1285-1297.
    • (2010) J Infect Dis , vol.201 , pp. 1285-1297
    • Tanton, C.1    Weiss, H.A.2    Rusizoka, M.3    Legoff, J.4    Changalucha, J.5
  • 24
    • 62349083377 scopus 로고    scopus 로고
    • Impact of aciclovir on genital and plasma HIV-1 RNA in HSV-2/HIV-1 co-infected women: a randomized placebo-controlled trial in South Africa
    • Delany S, Mlaba N, Clayton T, Akpomiemie G, Capovilla A, et al. (2009) Impact of aciclovir on genital and plasma HIV-1 RNA in HSV-2/HIV-1 co-infected women: a randomized placebo-controlled trial in South Africa. AIDS 23: 461-469.
    • (2009) AIDS , vol.23 , pp. 461-469
    • Delany, S.1    Mlaba, N.2    Clayton, T.3    Akpomiemie, G.4    Capovilla, A.5
  • 25
    • 77649279841 scopus 로고    scopus 로고
    • Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial
    • Lingappa JR, Baeten JM, Wald A, Hughes JP, Thomas KK, et al. (2010) Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial. Lancet 375: 824-833.
    • (2010) Lancet , vol.375 , pp. 824-833
    • Lingappa, J.R.1    Baeten, J.M.2    Wald, A.3    Hughes, J.P.4    Thomas, K.K.5
  • 26
    • 17344366114 scopus 로고    scopus 로고
    • Clinical efficacy of high-dose acyclovir in patients with human immunodeficiency virus infection: a meta-analysis of randomized individual patient data
    • Ioannidis JP, Collier AC, Cooper DA, Corey L, Fiddian AP, et al. (1998) Clinical efficacy of high-dose acyclovir in patients with human immunodeficiency virus infection: a meta-analysis of randomized individual patient data. J Infect Dis 178: 349-359.
    • (1998) J Infect Dis , vol.178 , pp. 349-359
    • Ioannidis, J.P.1    Collier, A.C.2    Cooper, D.A.3    Corey, L.4    Fiddian, A.P.5
  • 27
    • 33746041459 scopus 로고    scopus 로고
    • Management of herpes simplex virus type 2 infection in HIV type 1-infected persons
    • Strick LB, Wald A, Celum C, (2006) Management of herpes simplex virus type 2 infection in HIV type 1-infected persons. Clin Infect Dis 43: 347-356.
    • (2006) Clin Infect Dis , vol.43 , pp. 347-356
    • Strick, L.B.1    Wald, A.2    Celum, C.3
  • 28
    • 0024357248 scopus 로고
    • Development of clinically recognizable genital lesions among women previously identified as having "asymptomatic" herpes simplex virus type 2 infection
    • Langenberg A, Benedetti J, Jenkins J, Ashley R, Winter C, et al. (1989) Development of clinically recognizable genital lesions among women previously identified as having "asymptomatic" herpes simplex virus type 2 infection. Ann Intern Med 110: 882-887.
    • (1989) Ann Intern Med , vol.110 , pp. 882-887
    • Langenberg, A.1    Benedetti, J.2    Jenkins, J.3    Ashley, R.4    Winter, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.