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Volumn 23, Issue 8, 2011, Pages 503-510

Intracellular TLR4/MD-2 in macrophages senses Gram-negative bacteria and induces a unique set of LPS-dependent genes

Author keywords

Innate immunity; LPS; TLR

Indexed keywords

LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; RANTES; THIOGLYCOLIC ACID; TOLL LIKE RECEPTOR;

EID: 79960707808     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxr044     Document Type: Article
Times cited : (42)

References (31)
  • 1
    • 33646183566 scopus 로고    scopus 로고
    • Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large
    • Beutler, B., Jiang, Z., Georgel, P. et al. 2006. Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu. Rev. Immunol. 24:353.
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 353
    • Beutler, B.1    Jiang, Z.2    Georgel, P.3
  • 2
    • 33646147362 scopus 로고    scopus 로고
    • Toll-like receptor function and signaling
    • quiz 988
    • Kaisho, T. and Akira, S. 2006. Toll-like receptor function and signaling. J. Allergy Clin. Immunol. 117:979; quiz 988.
    • (2006) J. Allergy Clin. Immunol. , vol.117 , pp. 979
    • Kaisho, T.1    Akira, S.2
  • 3
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai, T. and Akira, S. 2010. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11:373.
    • (2010) Nat. Immunol. , vol.11 , pp. 373
    • Kawai, T.1    Akira, S.2
  • 4
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • Shimazu, R., Akashi, S., Ogata, H. et al. 1999. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189:1777.
    • (1999) J. Exp. Med. , vol.189 , pp. 1777
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3
  • 5
    • 34250813748 scopus 로고    scopus 로고
    • Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa
    • Ohto, U., Fukase, K., Miyake, K. and Satow, Y. 2007. Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa. Science 316:1632.
    • (2007) Science , vol.316 , pp. 1632
    • Ohto, U.1    Fukase, K.2    Miyake, K.3    Satow, Y.4
  • 6
    • 67349182481 scopus 로고    scopus 로고
    • The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
    • Park, B. S., Song, D. H., Kim, H. M., Choi, B. S., Lee, H. and Lee, J. O. 2009. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 458:1191.
    • (2009) Nature , vol.458 , pp. 1191
    • Park, B.S.1    Song, D.H.2    Kim, H.M.3    Choi, B.S.4    Lee, H.5    Lee, J.O.6
  • 8
    • 40949134086 scopus 로고    scopus 로고
    • TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta
    • Kagan, J. C., Su, T., Horng, T., Chow, A., Akira, S. and Medzhitov, R. 2008. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat. Immunol. 9:361.
    • (2008) Nat. Immunol. , vol.9 , pp. 361
    • Kagan, J.C.1    Su, T.2    Horng, T.3    Chow, A.4    Akira, S.5    Medzhitov, R.6
  • 9
    • 77958487596 scopus 로고    scopus 로고
    • The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
    • Husebye, H., Aune, M. H., Stenvik, J. et al. 2010. The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes. Immunity 33:583.
    • (2010) Immunity , vol.33 , pp. 583
    • Husebye, H.1    Aune, M.H.2    Stenvik, J.3
  • 10
    • 47149099757 scopus 로고    scopus 로고
    • Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling
    • Jain, V., Halle, A., Halmen, K. A. et al. 2008. Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling. Blood 111:4637.
    • (2008) Blood , vol.111 , pp. 4637
    • Jain, V.1    Halle, A.2    Halmen, K.A.3
  • 11
    • 41349102757 scopus 로고    scopus 로고
    • Soluble MD-2 is an acute-phase protein and an opsonin for Gramnegative bacteria
    • Tissieres, P., Dunn-Siegrist, I., Schappi, M. et al. 2008. Soluble MD-2 is an acute-phase protein and an opsonin for Gramnegative bacteria. Blood 111:2122.
    • (2008) Blood , vol.111 , pp. 2122
    • Tissieres, P.1    Dunn-Siegrist, I.2    Schappi, M.3
  • 12
    • 77958514610 scopus 로고    scopus 로고
    • Recycling endosomes and TLR signaling-the Rab11 GTPase leads the way
    • Kagan, J. C. 2010. Recycling endosomes and TLR signaling-the Rab11 GTPase leads the way. Immunity 33:578.
    • (2010) Immunity , vol.33 , pp. 578
    • Kagan, J.C.1
  • 13
    • 0036301797 scopus 로고    scopus 로고
    • Essential role of MD-2 in LPS responsiveness and TLR4 distribution
    • Nagai, Y., Akashi, S., Nagafuku, M. et al. 2002. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3:667.
    • (2002) Nat. Immunol. , vol.3 , pp. 667
    • Nagai, Y.1    Akashi, S.2    Nagafuku, M.3
  • 14
    • 34548608447 scopus 로고    scopus 로고
    • Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
    • Jin, M. S., Kim, S. E., Heo, J. Y. et al. 2007. Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell 130:1071.
    • (2007) Cell , vol.130 , pp. 1071
    • Jin, M.S.1    Kim, S.E.2    Heo, J.Y.3
  • 15
    • 70349506775 scopus 로고    scopus 로고
    • Mutational analysis of Cys(88) of Toll-like receptor 4 highlights the critical role of MD-2 in cell surface receptor expression
    • Nishitani, C., Takahashi, M., Mitsuzawa, H. et al. 2009. Mutational analysis of Cys(88) of Toll-like receptor 4 highlights the critical role of MD-2 in cell surface receptor expression. Int. Immunol. 21:925.
    • (2009) Int. Immunol. , vol.21 , pp. 925
    • Nishitani, C.1    Takahashi, M.2    Mitsuzawa, H.3
  • 16
    • 33746214788 scopus 로고    scopus 로고
    • A protein associated with Toll-like receptor 4 (PRAT4A) regulates cell surface expression of TLR4
    • Wakabayashi, Y., Kobayashi, M., Akashi-Takamura, S. et al. 2006. A protein associated with Toll-like receptor 4 (PRAT4A) regulates cell surface expression of TLR4. J. Immunol. 177:1772.
    • (2006) J. Immunol. , vol.177 , pp. 1772
    • Wakabayashi, Y.1    Kobayashi, M.2    Akashi-Takamura, S.3
  • 17
    • 3242708716 scopus 로고    scopus 로고
    • Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2
    • Jia, H. P., Kline, J. N., Penisten, A. et al. 2004. Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2. Am. J. Physiol. Lung Cell Mol. Physiol. 287:L428.
    • (2004) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.287
    • Jia, H.P.1    Kline, J.N.2    Penisten, A.3
  • 18
    • 36549072863 scopus 로고    scopus 로고
    • A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses
    • Takahashi, K., Shibata, T., Akashi-Takamura, S. et al. 2007. A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses. J. Exp. Med. 204:2963.
    • (2007) J. Exp. Med. , vol.204 , pp. 2963
    • Takahashi, K.1    Shibata, T.2    Akashi-Takamura, S.3
  • 19
    • 33847260278 scopus 로고    scopus 로고
    • Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages
    • Yang, Y., Liu, B., Dai, J. et al. 2007. Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages. Immunity 26:215.
    • (2007) Immunity , vol.26 , pp. 215
    • Yang, Y.1    Liu, B.2    Dai, J.3
  • 20
    • 84857475033 scopus 로고    scopus 로고
    • Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone
    • Liu, B., Yang, Y., Qiu, Z. et al. 2010. Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone. Nat. Commun. 1:79.
    • (2010) Nat. Commun. , vol.1 , pp. 79
    • Liu, B.1    Yang, Y.2    Qiu, Z.3
  • 21
    • 0141890200 scopus 로고    scopus 로고
    • Lipopolysaccharide interaction with cell surface toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14
    • Akashi, S., Saitoh, S.-I, Wakabayashi, Y. et al. 2003. Lipopolysaccharide interaction with cell surface toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14. J. Exp. Med. 198:1035.
    • (2003) J. Exp. Med. , vol.198 , pp. 1035
    • Akashi, S.1    Saitoh, S.-I.2    Wakabayashi, Y.3
  • 22
    • 0038448236 scopus 로고    scopus 로고
    • Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening
    • Hoebe, K., Du, X., Goode, J., Mann, N. and Beutler, B. 2003. Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening. J. Endotoxin. Res. 9:250.
    • (2003) J. Endotoxin. Res. , vol.9 , pp. 250
    • Hoebe, K.1    Du, X.2    Goode, J.3    Mann, N.4    Beutler, B.5
  • 23
    • 10744219675 scopus 로고    scopus 로고
    • TLR9 signals after translocating from the ER to CpG DNA in the lysosome
    • Latz, E., Schoenemeyer, A., Visintin, A. et al. 2004. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat. Immunol. 5:190.
    • (2004) Nat. Immunol. , vol.5 , pp. 190
    • Latz, E.1    Schoenemeyer, A.2    Visintin, A.3
  • 24
    • 0025874032 scopus 로고
    • Recognition and plasma clearance of endotoxin by scavenger receptors
    • Hampton, R. Y., Golenbock, D. T., Penman, M., Krieger, M. and Raetz, C. R. 1991. Recognition and plasma clearance of endotoxin by scavenger receptors. Nature 352:342.
    • (1991) Nature , vol.352 , pp. 342
    • Hampton, R.Y.1    Golenbock, D.T.2    Penman, M.3    Krieger, M.4    Raetz, C.R.5
  • 25
    • 3142690482 scopus 로고    scopus 로고
    • TLR4 is the signaling but not the lipopolysaccharide uptake receptor
    • Dunzendorfer, S., Lee, H. K., Soldau, K. and Tobias, P. S. 2004. TLR4 is the signaling but not the lipopolysaccharide uptake receptor. J. Immunol. 173:1166.
    • (2004) J. Immunol. , vol.173 , pp. 1166
    • Dunzendorfer, S.1    Lee, H.K.2    Soldau, K.3    Tobias, P.S.4
  • 26
    • 0033575792 scopus 로고    scopus 로고
    • Transport of bacterial lipopolysaccharide to the golgi apparatus
    • Thieblemont, N. and Wright, S. D. 1999. Transport of bacterial lipopolysaccharide to the golgi apparatus. J. Exp. Med. 190:523.
    • (1999) J. Exp. Med. , vol.190 , pp. 523
    • Thieblemont, N.1    Wright, S.D.2
  • 27
    • 34948862264 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
    • Lande, R., Gregorio, J., Facchinetti, V. et al. 2007. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature 449:564.
    • (2007) Nature , vol.449 , pp. 564
    • Lande, R.1    Gregorio, J.2    Facchinetti, V.3
  • 28
    • 34247891509 scopus 로고    scopus 로고
    • Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease
    • Marshak-Rothstein, A. and Rifkin, I. R. 2007. Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Annu. Rev. Immunol. 25:419.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 419
    • Marshak-Rothstein, A.1    Rifkin, I.R.2
  • 29
    • 33947629255 scopus 로고    scopus 로고
    • Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
    • Miyake, K. 2007. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin. Immunol. 19:3.
    • (2007) Semin. Immunol. , vol.19 , pp. 3
    • Miyake, K.1
  • 30
    • 0346734122 scopus 로고    scopus 로고
    • Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases
    • Liu, B., Dai, J., Zheng, H., Stoilova, D., Sun, S. and Li, Z. 2003. Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases. Proc. Natl Acad. Sci. USA 100:15824.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 15824
    • Liu, B.1    Dai, J.2    Zheng, H.3    Stoilova, D.4    Sun, S.5    Li, Z.6
  • 31
    • 29044448973 scopus 로고    scopus 로고
    • A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression
    • Konno, K., Wakabayashi, Y., Akashi-Takamura, S. et al. 2006. A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression. Biochem. Biophys. Res. Commun. 339:1076.
    • (2006) Biochem. Biophys. Res. Commun. , vol.339 , pp. 1076
    • Konno, K.1    Wakabayashi, Y.2    Akashi-Takamura, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.