No overt influence of lymphadenectomy on cancer-specific survival in organ-confined versus locally advanced upper urinary tract urothelial carcinoma undergoing radical nephroureterectomy: A retrospective international, multi-institutional study

World Journal of Urology

Volumn 29, Issue 4, 2011, Pages 465-472

  Burger, Maximilian ^a   Shariat, Shahrokh F ^b   Fritsche, Hans Martin ^a   Martinez Salamanca, Juan Ignacio ^c   Matsumoto, Kazumasa ^d   Chromecki, Thomas F ^b   Ficarra, Vincenzo ^e   Kassouf, Wassim ^f   Seitz, Christian ^g   Pycha, Armin ^g   Tritschler, Stefan ^h   Walton, Thomas J ⁱ   Novara, Giacomo ^e  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

^d KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF PADOVA   (Italy)

^f MCGILL UNIVERSITY   (Canada)

^g CENTRAL HOSPITAL OF BOLZANO   (Italy)

^h LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

ⁱ DERBY CITY GENERAL HOSPITAL   (United Kingdom)

Author keywords

Lymph node; Lymphadenectomy; Nephroureterectomy; Survival; Urothelial carcinoma

Indexed keywords

AGED; ARTICLE; CARCINOMA; CLINICAL TRIAL; COMPARATIVE STUDY; FEMALE; HUMAN; INTERNATIONAL COOPERATION; KAPLAN MEIER METHOD; LYMPHADENECTOMY; MALE; METHODOLOGY; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; NEPHRON; PATHOLOGY; PROGNOSIS; REGRESSION ANALYSIS; RETROSPECTIVE STUDY; SURVIVAL RATE; TREATMENT OUTCOME; URETER; URINARY TRACT CANCER; UROLOGIC SURGERY; UROTHELIUM;

AGED; CARCINOMA; FEMALE; HUMANS; INTERNATIONAL COOPERATION; KAPLAN-MEIER ESTIMATE; LYMPH NODE EXCISION; MALE; MIDDLE AGED; NEPHRONS; PROGNOSIS; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME; URETER; UROLOGIC NEOPLASMS; UROLOGIC SURGICAL PROCEDURES; UROTHELIUM;

EID: 79960698780     PISSN: 07244983     EISSN: 14338726     Source Type: Journal    
DOI: 10.1007/s00345-011-0705-0     Document Type: Article

References (26)

1. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ (2007) Cancer statistics, 2007. CA Cancer J Clin 57: 43.
2. NCCN clinical practice guidelines in oncology: bladder cancer. Including upper tract tumors and urothelial carcinoma of the prostate. V. 1. 2010. National Comprehensive Cancer Network Web site. http://www. nccn. org/professionals/physician_gls/f_guidelines. asp.
3. Rouprêt M, Zigeuner R, Palou J, Boehle A, Kaasinen E, Sylvester R, Babjuk M, Oosterlinck W (2011) European guidelines for the diagnosis and management of upper urinary tract urothelial cell carcinomas: 2011 Update. Eur Urol.
4. Cornu JN, Rouprêt M, Carpentier X, Geavlete B, de Medina SG, Cussenot O, Traxer O (2010) Oncologic control obtained after exclusive flexible ureteroscopic management of upper urinary tract urothelial cell carcinoma. World J Urol 28(2): 151-156.
5. Stenzl A, Cowan NC, De Santis M, Jakse G, Kuczyk MA, Merseburger AS, Ribal MJ, Sherif A, Witjes JA (2009) The updated EAU guidelines on muscle-invasive and metastatic bladder cancer. Eur Urol 55(4): 815-825.
6. Dhar NB, Klein EA, Reuther AM, Thalmann GN, Madersbacher S, Studer UE (2008) Outcome after radical cystectomy with limited or extended pelvic lymph node dissection. J Urol 179(3): 873-878.
7. Manoharan M, Katkoori D, Kishore TA, Jorda M, Luongo T, Soloway MS (2010) Lymphovascular invasion in radical cystectomy specimen: is it an independent prognostic factor in patients without lymph node metastases? World J Urol 28(2): 233-237.
8. Holmer M, Bendahl PO, Davidsson T, Gudjonsson S, Månsson W, Liedberg F (2009) Extended lymph node dissection in patients with urothelial cell carcinoma of the bladder: can it make a difference? World J Urol 27(4): 521-526.
9. Karl A, Carroll PR, Gschwend JE, Knüchel R, Montorsi F, Stief CG, Studer UE (2009) The impact of lymphadenectomy and lymph node metastasis on the outcomes of radical cystectomy for bladder cancer. Eur Urol 55(4): 826-835.
10. Zigeuner R, Pummer K (2008) Urothelial carcinoma of the upper urinary tract: surgical approach and prognostic factors. Eur Urol 53(4): 720-731.
11. Capitanio U, Shariat SF, Isbarn H, Weizer A, Remzi M, Roscigno M, Kikuchi E, Raman JD, Bolenz C, Bensalah K, Koppie TM, Kassouf W, Fernández MI, Ströbel P, Wheat J, Zigeuner R, Langner C, Waldert M, Oya M, Guo CC, Ng C, Montorsi F, Wood CG, Margulis V, Karakiewicz PI (2009) Comparison of oncologic outcomes for open and laparoscopic nephroureterectomy: a multi-institutional analysis of 1249 cases. Eur Urol 56(1): 1-9.
12. Novara G, De Marco V, Gottardo F, Dalpiaz O, Bouygues V, Galfano A, Martignoni G, Patard JJ, Artibani W, Ficarra V (2007) Independent predictors of cancer-specific survival in transitional cell carcinoma of the upper urinary tract: multi-institutional dataset from 3 European centres. Cancer 110(8): 1715-1722.
13. Novara G, Matsumoto K, Kassouf W, Walton TJ, Fritsche HM, Bastian PJ, Martínez-Salamanca JI, Seitz C, Lemberger RJ, Burger M, El-Hakim A, Baba S, Martignoni G, Gupta A, Karakiewicz PI, Ficarra V, Shariat SF (2010) Prognostic role of lymphovascular invasion in patients with urothelial carcinoma of the upper urinary tract: an international validation study. Eur Urol 57(6): 1064-1067.
14. Roscigno M, Shariat SF, Freschi M, Margulis V, Karakiewizc P, Suardi N, Remzi M, Zigeuner R, Bolenz C, Kikuchi E, Weizer A, Bensalah K, Sagalowsky A, Koppie TM, Raman J, Fernández M, Ströbel P, Kabbani W, Langner C, Wheat J, Guo CC, Kassouf W, Haitel A, Wood CG, Montorsi F (2009) Assessment of the minimum number of lymph nodes needed to detect lymph node invasion at radical nephroureterectomy in patients with upper tract urothelial cancer. Urology 74(5): 1070-1074.
15. Margulis V, Shariat SF, Matin SF, Kamat AM, Zigeuner R, Kikuchi E, Lotan Y, Weizer A, Raman JD, Wood CG (2009) Upper tract urothelial carcinoma collaboration the upper tract urothelial carcinoma collaboration. Outcomes of radical nephroureterectomy: a series from the upper tract urothelial carcinoma collaboration. Cancer 115(6): 1224-1233.
16. Kondo T, Nakazawa H, Ito F, Hashimoto Y, Toma H, Tanabe K (2007) Impact of the extent of regional lymphadenectomy on the survival of patients with urothelial carcinoma of the upper urinary tract. J Urol 178: 1212.
17. Brausi MA, Gavioli M, De Luca G, Verrini G, Peracchia G, Simonini G et al (2007) Retroperitoneal lymph node dissection (RPLD) in conjunction with nephroureterectomy in the treatment of infiltrative transitional cell carcinoma (TCC) of the upper urinary tract: impact on survival. Eur Urol 52: 1414.
18. Roscigno M, Cozzarini C, Bertini R, Scattoni V, Freschi M, Da Pozzo LF et al (2008) Prognostic value of lymph node dissection in patients with muscle-invasive transitional cell carcinoma of the upper urinary tract. Eur Urol 53: 794.
19. Roscigno M, Shariat SF, Margulis V, Karakiewicz P, Remzi M, Kikuchi E, Langner C, Lotan Y, Weizer A, Bensalah K, Raman JD, Bolenz C, Guo CC, Wood CG, Zigeuner R, Wheat J, Kabbani W, Koppie TM, Ng CK, Suardi N, Bertini R, Fernández MI, Mikami S, Isida M, Michel MS, Montorsi F (2009) Impact of lymph node dissection on cancer specific survival in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy. J Urol 181(6): 2482-2489.
20. Lughezzani G, Jeldres C, Isbarn H, Shariat SF, Sun M, Pharand D, Widmer H, Arjane P, Graefen M, Montorsi F, Perrotte P, Karakiewicz PI (2010) A critical appraisal of the value of lymph node dissection at nephroureterectomy for upper tract urothelial carcinoma. Urology 75(1): 118-124.
21. Greene FL, Gospodarowicz M, Wittekind C et al (2009) American Joint Committee on Cancer (AJCC) staging manual, 7th edn. Springer, Philadelphia.
22. Mostofi FK, Sobin LH, Torloni H (1973) Histological typing of urinary bladder tumours. World Health Organization, Geneva.
23. Margulis V, Youssef RF, Karakiewicz PI et al (2010) Preoperative multivariable prognostic model for prediction of nonorgan confined urothelial carcinoma of the upper urinary tract. J Urol 184(2): 453-458.
24. Feinstein AR, Sosin DM, Wells CK (1985) The Will Rogers phenomenon. Stage migration, new diagnostic techniques as a source of misleading statistics for survival in cancer. N Engl J Med 312: 1604.
25. Shariat SF, Favaretto RL, Gupta A, Fritsche HM, Matsumoto K, Kassouf W, Walton TJ, Tritschler S, Baba S, Matsushita K, Bastian PJ, Martínez-Salamanca JI, Seitz C, Pycha A, Otto W, Karakiewicz PI, Ficarra V, Novara G (1 Oct 2010) Gender differences in radical nephroureterectomy for upper tract urothelial carcinoma. World J Urol [Epub ahead of print].
26. Otto W, Shariat SF, Fritsche HM, Gupta A, Matsumoto K, Kassouf W, Martignoni G, Walton TJ, Tritschler S, Baba S, Bastian PJ, Martínez-Salamanca JI, Seitz C, Pycha A, Burger M, Karakiewicz PI, Ficarra V, Novara G (20 Jan 2011) Concomitant carcinoma in situ as an independent prognostic parameter for recurrence and survival in upper tract urothelial carcinoma: a multicentre analysis of 772 patients. World J Urol [Epub ahead of print].