-
1
-
-
77953888624
-
Trabectedin for advanced sarcomas failing doxorubicin: Analysis of 189 unreported patients in a compassionate use program [abstract]
-
Abstract 10574.
-
Blay J, Penel N, Italiano A, et al. Trabectedin for advanced sarcomas failing doxorubicin: analysis of 189 unreported patients in a compassionate use program [abstract]. J Clin Oncol. 2009; 27 (15S). Abstract 10574.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15
-
-
Blay, J.1
Penel, N.2
Italiano, A.3
-
2
-
-
70249101414
-
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: Results of a randomized phase II study of 2 different schedules
-
Demetri GD, Chawla SP, von Mehren M, et al. Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of 2 different schedules. J Clin Oncol. 2009; 27: 4188-4196.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4188-4196
-
-
Demetri, G.D.1
Chawla, S.P.2
Von Mehren, M.3
-
3
-
-
2342461682
-
Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy
-
DOI 10.1200/JCO.2004.02.098
-
Garcia-Carbonero R, Supko JG, Manola J, et al. Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J Clin Oncol. 2004; 22: 1480-1490. (Pubitemid 41103631)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.8
, pp. 1480-1490
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
Manola, J.3
Seiden, M.V.4
Hannon, D.5
Ryan, D.P.6
Quigley, M.T.7
Merriam, P.8
Canniff, J.9
Goss, G.10
Matulonis, U.11
Maki, R.G.12
Lopez, T.13
Puchalski, T.A.14
Sancho, M.A.15
Gomez, J.16
Guzman, C.17
Jimeno, J.18
Demetri, G.D.19
-
4
-
-
20044372153
-
Phase II study of ET-743 in advanced soft tissue sarcomas: A European Organisation for the Research and Treatment of Cancer (EORTC) Soft Tissue and Bone Sarcoma Group trial
-
DOI 10.1200/JCO.2005.01.180
-
Le Cesne A, Blay JY, Judson I, et al. Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) Soft Tissue and Bone Sarcoma Group trial. J Clin Oncol. 2005; 23: 576-584. (Pubitemid 46224235)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.3
, pp. 576-584
-
-
Blay, J.Y.1
Judson, I.2
Van Oosterom, A.3
Verweij, J.4
Radford, J.5
Lorigan, P.6
Rodenhuis, S.7
Ray-Coquard, I.8
Bonvalot, S.9
Collin, F.10
Jimeno, J.11
Di Paola, E.12
Van Glabbeke, M.13
Nielsen, O.S.14
Cesne, A.L.15
-
5
-
-
1542398698
-
Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients
-
DOI 10.1200/JCO.2004.05.210
-
Yovine A, Riofrio M, Blay JY, et al. Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients. J Clin Oncol. 2004; 22: 890-899. (Pubitemid 41103601)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.5
, pp. 890-899
-
-
Yovine, A.1
Riofrio, M.2
Blay, J.Y.3
Brain, E.4
Alexandre, J.5
Kahatt, C.6
Taamma, A.7
Jimeno, J.8
Martin, C.9
Salhi, Y.10
Cvitkovic, E.11
Misset, J.L.12
-
6
-
-
0035874074
-
Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways
-
DOI 10.1002/ijc.1221
-
Damia G, Silvestri S, Carrassa L, et al. Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways. Int J Cancer. 2001; 92: 583-588. (Pubitemid 32319434)
-
(2001)
International Journal of Cancer
, vol.92
, Issue.4
, pp. 583-588
-
-
Damia, G.1
Silvestri, S.2
Carrassa, L.3
Filiberti, L.4
Faircloth, G.T.5
Liberi, G.6
Foiani, M.7
D'Incalci, M.8
-
7
-
-
0035146702
-
Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action
-
PII S0959804900003579
-
Erba E, Bergamaschi D, Bassano L, et al. Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action. Eur J Cancer. 2001; 37: 97-105. (Pubitemid 32119366)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.1
, pp. 97-105
-
-
Erba, E.1
Bergamaschi, D.2
Bassano, L.3
Damia, G.4
Ronzoni, S.5
Faircloth, G.T.6
D'Incalci, M.7
-
8
-
-
33748035692
-
Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin
-
DOI 10.1158/0008-5472.CAN-06-0179
-
Herrero AB, Martin-Castellanos C, Marco E, Gago F, Moreno S., Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin. Cancer Res. 2006; 66: 8155-8162. (Pubitemid 44299183)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 8155-8162
-
-
Herrero, A.B.1
Martin-Castellanos, C.2
Marco, E.3
Gago, F.4
Moreno, S.5
-
9
-
-
34548706418
-
Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743
-
DOI 10.1073/pnas.0609877104
-
Soares DG, Escargueil AE, Poindessous V, et al. Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743. Proc Natl Acad Sci U S A. 2007; 104: 13062-13067. (Pubitemid 351737593)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.32
, pp. 13062-13067
-
-
Soares, D.G.1
Escargueil, A.E.2
Poindessous, V.3
Sarasin, A.4
De Gramont, A.5
Bonatto, D.6
Henriques, J.A.P.7
Larsen, A.K.8
-
10
-
-
17944374027
-
Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair
-
DOI 10.1038/91008
-
Takebayashi Y, Pourquier P, Zimonjic DB, et al. Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair. Nat Med. 2001; 7: 961-966. (Pubitemid 32756435)
-
(2001)
Nature Medicine
, vol.7
, Issue.8
, pp. 961-966
-
-
Takebayashi, Y.1
Pourquier, P.2
Zimonjic, D.B.3
Nakayama, K.4
Emmert, S.5
Ueda, T.6
Urasaki, Y.7
Kanzaki, A.8
Akiyama, S.-I.9
Popescu, N.10
Kraemer, K.H.11
Pommier, Y.12
-
11
-
-
70349859881
-
DNA damage, aging, and cancer
-
Hoeijmakers JH., DNA damage, aging, and cancer. N Engl J Med. 2009; 361: 1475-1485.
-
(2009)
N Engl J Med
, vol.361
, pp. 1475-1485
-
-
Hoeijmakers, J.H.1
-
12
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan ME, Jasin M., Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol. 2010; 11: 196-207.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
13
-
-
18444404938
-
Unique features of the mode of action of ET-743
-
DOI 10.1634/theoncologist.7-3-210
-
D'Incalci M, Erba E, Damia G, et al. Unique features of the mode of action of ET-743. Oncologist. 2002; 7: 210-216. (Pubitemid 34651224)
-
(2002)
Oncologist
, vol.7
, Issue.3
, pp. 210-216
-
-
D'Incalci, M.1
Erba, E.2
Damia, G.3
Galliera, E.4
Carrassa, L.5
Marchini, S.6
Mantovani, R.7
Tognon, G.8
Fruscio, R.9
Jimeno, J.10
Faircloth, G.T.11
-
14
-
-
38349186343
-
Predicting cisplatin and trabectedin drug sensitivity in ovarian and colon cancers
-
Stevens EV, Nishizuka S, Antony S, et al. Predicting cisplatin and trabectedin drug sensitivity in ovarian and colon cancers. Mol Cancer Ther. 2008; 7: 10-18.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 10-18
-
-
Stevens, E.V.1
Nishizuka, S.2
Antony, S.3
-
15
-
-
75149189204
-
BRCA1 and its toolbox for the maintenance of genome integrity
-
Huen MS, Sy SM, Chen J., BRCA1 and its toolbox for the maintenance of genome integrity. Nat Rev Mol Cell Biol. 2009; 11: 138-148.
-
(2009)
Nat Rev Mol Cell Biol
, vol.11
, pp. 138-148
-
-
Huen, M.S.1
Sy, S.M.2
Chen, J.3
-
16
-
-
20044396161
-
Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naïve patients
-
DOI 10.1158/1535-7163.MCT-04-0316
-
Martinez N, Sanchez-Beato M, Carnero A, et al. Transcriptional signature of ecteinascidin 743 (Yondelis, trabectedin) in human sarcoma cells explanted from chemo-naive patients. Mol Cancer Ther. 2005; 4: 814-823. (Pubitemid 40767126)
-
(2005)
Molecular Cancer Therapeutics
, vol.4
, Issue.5
, pp. 814-823
-
-
Martinez, N.1
Sanchez-Beato, M.2
Carnero, A.3
Moneo, V.4
Tercero, J.C.5
Fernandez, I.6
Navarrete, M.7
Jimeno, J.8
Piris, M.A.9
-
17
-
-
37249019507
-
Cancer pharmacogenomics: Role of DNA repair genetic polymorphisms in individualizing cancer therapy
-
Gossage L, Madhusudan S., Cancer pharmacogenomics: role of DNA repair genetic polymorphisms in individualizing cancer therapy. Mol Diagn Ther. 2007; 11: 361-380. (Pubitemid 350274404)
-
(2007)
Molecular Diagnosis and Therapy
, vol.11
, Issue.6
, pp. 361-380
-
-
Gossage, L.1
Madhusudan, S.2
-
18
-
-
18844409128
-
Predicting drug response and toxicity based on gene polymorphisms
-
DOI 10.1016/j.critrevonc.2005.01.005, PII S1040842805000314
-
Robert J, Morvan VL, Smith D, Pourquier P, Bonnet J., Predicting drug response and toxicity based on gene polymorphisms. Crit Rev Oncol Hematol. 2005; 54: 171-196. (Pubitemid 40693684)
-
(2005)
Critical Reviews in Oncology/Hematology
, vol.54
, Issue.3
, pp. 171-196
-
-
Robert, J.1
Le Morvan, V.2
Smith, D.3
Pourquier, P.4
Bonnet, J.5
-
19
-
-
0036183054
-
Molecular detection of the synovial sarcoma translocation t(X;18) by real-time polymerase chain reaction in paraffin-embedded material
-
DOI 10.1097/00019606-200203000-00004
-
Hostein I, Menard A, Bui BN, et al. Molecular detection of the synovial sarcoma translocation t(X;18) by real-time polymerase chain reaction in paraffin-embedded material. Diagn Mol Pathol. 2002; 11: 16-21. (Pubitemid 34171207)
-
(2002)
Diagnostic Molecular Pathology
, vol.11
, Issue.1
, pp. 16-21
-
-
Hostein, I.1
Menard, A.2
Bui, B.N.3
Lussan, C.4
Wafflart, J.5
Delattre, O.6
Peter, M.7
Benhattar, J.8
Guillou, L.9
Coindre, J.-M.10
-
20
-
-
0030990434
-
A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function
-
DOI 10.1073/pnas.94.7.3116
-
Nouspikel T, Lalle P, Leadon SA, Cooper PK, Clarkson SG., A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: implications for a second XPG function. Proc Natl Acad Sci U S A. 1997; 94: 3116-3121. (Pubitemid 27157273)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.7
, pp. 3116-3121
-
-
Nouspikel, T.1
Lalle, P.2
Leadon, S.A.3
Cooper, P.K.4
Clarkson, S.G.5
-
21
-
-
58049209898
-
Effect of BRCA1 haplotype on survival of non-small-cell lung cancer patients treated with platinum-based chemotherapy
-
Kim HT, Lee JE, Shin ES, et al. Effect of BRCA1 haplotype on survival of non-small-cell lung cancer patients treated with platinum-based chemotherapy. J Clin Oncol. 2008; 26: 5972-5979.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5972-5979
-
-
Kim, H.T.1
Lee, J.E.2
Shin, E.S.3
-
22
-
-
77953214042
-
BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin
-
Shim HJ, Yun JY, Hwang JE, et al. BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin. Cancer Sci. 2010; 101: 1247-1254.
-
(2010)
Cancer Sci
, vol.101
, pp. 1247-1254
-
-
Shim, H.J.1
Yun, J.Y.2
Hwang, J.E.3
-
23
-
-
63049110664
-
Excision repair cross-complementation group 1 (ERCC1) in platinum-based treatment of non-small cell lung cancer with special emphasis on carboplatin: A review of current literature
-
Vilmar A, Sorensen JB., Excision repair cross-complementation group 1 (ERCC1) in platinum-based treatment of non-small cell lung cancer with special emphasis on carboplatin: a review of current literature. Lung Cancer. 2009; 64: 131-139.
-
(2009)
Lung Cancer
, vol.64
, pp. 131-139
-
-
Vilmar, A.1
Sorensen, J.B.2
-
24
-
-
24344479165
-
ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer
-
DOI 10.1158/1078-0432.CCR-04-2216
-
Viguier J, Boige V, Miquel C, et al. ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer. Clin Cancer Res. 2005; 11: 6212-6217. (Pubitemid 41262950)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.17
, pp. 6212-6217
-
-
Viguier, J.1
Boige, V.2
Miquel, C.3
Pocard, M.4
Giraudeau, B.5
Sabourin, J.-C.6
Ducreux, M.7
Sarasin, A.8
Praz, F.9
-
25
-
-
79960697034
-
Trabectedin in soft tissue sarcomas (STS) carrying a chromosomal translocation: An exploratory analysis. Abstract 900. Paper presented at: Connective Tissue Oncology Society (CTOS) 13th Annual Meeting; November 1-3, 2007; Seattle
-
Grosso F., Trabectedin in soft tissue sarcomas (STS) carrying a chromosomal translocation: an exploratory analysis. Abstract 900. Paper presented at: Connective Tissue Oncology Society (CTOS) 13th Annual Meeting; November 1-3, 2007; Seattle, Wash.
-
Wash
-
-
Grosso, F.1
-
26
-
-
69449106265
-
Trabectedin in myxoid liposarcomas (MLS): A long-term analysis of a single-institution series
-
Grosso F, Sanfilippo R, Virdis E, et al. Trabectedin in myxoid liposarcomas (MLS): a long-term analysis of a single-institution series. Ann Oncol. 2009; 20: 1439-1444.
-
(2009)
Ann Oncol
, vol.20
, pp. 1439-1444
-
-
Grosso, F.1
Sanfilippo, R.2
Virdis, E.3
-
27
-
-
60849129809
-
Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors
-
Forni C, Minuzzo M, Virdis E, et al. Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors. Mol Cancer Ther. 2009; 8: 449-457.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 449-457
-
-
Forni, C.1
Minuzzo, M.2
Virdis, E.3
-
28
-
-
0037403380
-
Improved survival in women with BRCA-associated ovarian carcinoma
-
DOI 10.1002/cncr.11310
-
Cass I, Baldwin RL, Varkey T, Moslehi R, Narod SA, Karlan BY., Improved survival in women with BRCA-associated ovarian carcinoma. Cancer. 2003; 97: 2187-2195. (Pubitemid 36444059)
-
(2003)
Cancer
, vol.97
, Issue.9
, pp. 2187-2195
-
-
Cass, I.1
Baldwin, R.L.2
Varkey, T.3
Moslehi, R.4
Narod, S.A.5
Karlan, B.Y.6
-
29
-
-
0036341143
-
A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer
-
Chappuis PO, Goffin J, Wong N, et al. A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer. J Med Genet. 2002; 39: 608-610. (Pubitemid 34864568)
-
(2002)
Journal of Medical Genetics
, vol.39
, Issue.8
, pp. 608-610
-
-
Chappuis, P.O.1
Goffin, J.2
Wong, N.3
Perret, C.4
Ghadirian, P.5
Tonin, P.N.6
Foulkes, W.D.7
-
30
-
-
0037303255
-
Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10-Year follow-up data
-
DOI 10.1002/cncr.11080
-
Goffin JR, Chappuis PO, Begin LR, et al. Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10-year follow-up data. Cancer. 2003; 97: 527-536. (Pubitemid 36125829)
-
(2003)
Cancer
, vol.97
, Issue.3
, pp. 527-536
-
-
Goffin, J.R.1
Chappuis, P.O.2
Begin, L.R.3
Wong, N.4
Brunet, J.-S.5
Hamel, N.6
Paradis, A.-J.7
Boyd, J.8
Foulkes, W.D.9
-
31
-
-
26244453280
-
Risk of breast cancer recurrence and contralateral breast cancer in relation to BRCA1 and BRCA2 mutation status following breast-conserving surgery and radiotherapy
-
DOI 10.1016/j.ejca.2005.02.037, PII S0959804905006027
-
Kirova YM, Stoppa-Lyonnet D, Savignoni A, Sigal-Zafrani B, Fabre N, Fourquet A., Risk of breast cancer recurrence and contralateral breast cancer in relation to BRCA1 and BRCA2 mutation status following breast-conserving surgery and radiotherapy. Eur J Cancer. 2005; 41: 2304-2311. (Pubitemid 41415607)
-
(2005)
European Journal of Cancer
, vol.41
, Issue.15
, pp. 2304-2311
-
-
Kirova, Y.M.1
Stoppa-Lyonnet, D.2
Savignoni, A.3
Sigal-Zafrani, B.4
Fabre, N.5
Fourquet, A.6
-
32
-
-
77954535843
-
Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity
-
Chibon F, Lagarde P, Salas S, et al. Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity. Nat Med. 2010; 16: 781-787.
-
(2010)
Nat Med
, vol.16
, pp. 781-787
-
-
Chibon, F.1
Lagarde, P.2
Salas, S.3
|