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Volumn 53, Issue 2, 2011, Pages 91-98

MicroRNAs in bipolar disorder: Diagnostic and therapeutic applications;MicroARN en el trastorno bipolar: Posibles aplicaciones diagnósticas y terapéuticas

Author keywords

Bipolar disorder; Genetics; Lithium; MicroRNA; MiRNA; Valproate

Indexed keywords

LITHIUM; MICRORNA; VALPROIC ACID;

EID: 79960684150     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.5302.2010661     Document Type: Review
Times cited : (6)

References (60)
  • 2
    • 0034471976 scopus 로고    scopus 로고
    • Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders
    • Akiskal HS, Bourgeois ML, Angst J, Post R, Moller H, Hirschfeld R. Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders. J Affect Disord 2000; 59 (Suppl 1): S5-30.
    • (2000) J Affect Disord , vol.59 , Issue.SUPPL 1
    • Akiskal, H.S.1    Bourgeois, M.L.2    Angst, J.3    Post, R.4    Moller, H.5    Hirschfeld, R.6
  • 5
    • 33646343938 scopus 로고    scopus 로고
    • The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: Evidence that they lie on a dimensional spectrum
    • Akiskal HS, Benazzi F. The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum. J Affect Disord 2006; 92: 45-54.
    • (2006) J Affect Disord , vol.92 , pp. 45-54
    • Akiskal, H.S.1    Benazzi, F.2
  • 6
    • 67749091002 scopus 로고    scopus 로고
    • Searching genetic risk factors for schizophrenia and bipolar disorder: Learn from the past and back to the future
    • Alaerts M, Del Favero J. Searching genetic risk factors for schizophrenia and bipolar disorder: learn from the past and back to the future. Hum Mutat 2009; 30: 1139-52.
    • (2009) Hum Mutat , vol.30 , pp. 1139-1152
    • Alaerts, M.1    del Favero, J.2
  • 7
    • 0036785078 scopus 로고    scopus 로고
    • Have we undersold lithium for bipolar disorder?
    • Pies R. Have we undersold lithium for bipolar disorder? J Clin Psychopharmacol 2002; 22: 445-9.
    • (2002) J Clin Psychopharmacol , vol.22 , pp. 445-449
    • Pies, R.1
  • 8
    • 0036394114 scopus 로고    scopus 로고
    • Rationale for long-term treatment of bipolar disorder and evidence for long-term lithium treatment
    • Goodwin FK. Rationale for long-term treatment of bipolar disorder and evidence for long-term lithium treatment. J Clin Psychiatry 2002; 63 (Suppl 10): S5-12.
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL 10
    • Goodwin, F.K.1
  • 9
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
    • Catterall WA. From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 2000; 26: 13-25.
    • (2000) Neuron , vol.26 , pp. 13-25
    • Catterall, W.A.1
  • 10
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen G, Zeng WZ, Yuan PX, Huang LD, Jiang YM, Zhao ZH, et al. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem 1999; 72: 879-82.
    • (1999) J Neurochem , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.Z.2    Yuan, P.X.3    Huang, L.D.4    Jiang, Y.M.5    Zhao, Z.H.6
  • 11
    • 79960684089 scopus 로고    scopus 로고
    • Bipolar disorder: Neurochemistry and drug mechanisms
    • Belmaker RH, Agam G. Bipolar disorder: neurochemistry and drug mechanisms. Discovery Medicine 2005; 5: 191-8.
    • (2005) Discovery Medicine , vol.5 , pp. 191-198
    • Belmaker, R.H.1    Agam, G.2
  • 12
    • 73749084665 scopus 로고    scopus 로고
    • The genetics of bipolar disorder
    • Barnett JH, Smoller JW. The genetics of bipolar disorder. Neuroscience 2009; 164: 331-43.
    • (2009) Neuroscience , vol.164 , pp. 331-343
    • Barnett, J.H.1    Smoller, J.W.2
  • 13
    • 77049125519 scopus 로고    scopus 로고
    • Genetic research into bipolar disorder: The need for a research framework that integrates sophisticated molecular biology and clinically informed phenotype characterization
    • Schulze TG. Genetic research into bipolar disorder: the need for a research framework that integrates sophisticated molecular biology and clinically informed phenotype characterization. Psychiatr Clin North Am 2010; 33: 67-82.
    • (2010) Psychiatr Clin North Am , vol.33 , pp. 67-82
    • Schulze, T.G.1
  • 14
    • 25444466232 scopus 로고    scopus 로고
    • Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q
    • McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, et al. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet 2005; 77: 582-95.
    • (2005) Am J Hum Genet , vol.77 , pp. 582-595
    • McQueen, M.B.1    Devlin, B.2    Faraone, S.V.3    Nimgaonkar, V.L.4    Sklar, P.5    Smoller, J.W.6
  • 15
    • 47749156793 scopus 로고    scopus 로고
    • The genetics of bipolar disorder: Genome 'hot regions' genes, new potential candidates and future directions
    • Serretti A, Mandelli L. The genetics of bipolar disorder: genome 'hot regions' genes, new potential candidates and future directions. Mol Psychiatry 2008; 13: 742-71.
    • (2008) Mol Psychiatry , vol.13 , pp. 742-771
    • Serretti, A.1    Mandelli, L.2
  • 17
    • 72849127300 scopus 로고    scopus 로고
    • Melatonin, circadian rhythms, and the clock genes in bipolar disorder
    • Dallaspezia S, Benedetti F. Melatonin, circadian rhythms, and the clock genes in bipolar disorder. Curr Psychiatry Rep 2009; 11: 488-93.
    • (2009) Curr Psychiatry Rep , vol.11 , pp. 488-493
    • Dallaspezia, S.1    Benedetti, F.2
  • 18
    • 38349128462 scopus 로고    scopus 로고
    • A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
    • Baum AE, Akula N, Cabanero M, Cardona I, Corona W, Klemens B, et al. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry 2008; 13: 197-207.
    • (2008) Mol Psychiatry , vol.13 , pp. 197-207
    • Baum, A.E.1    Akula, N.2    Cabanero, M.3    Cardona, I.4    Corona, W.5    Klemens, B.6
  • 19
    • 77956650793 scopus 로고    scopus 로고
    • Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness)
    • Le-Niculescu H, Patel SD, Niculescu AB. Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness). Curr Opin Pharmacol 2010; 10: 594-600.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 594-600
    • Le-Niculescu, H.1    Patel, S.D.2    Niculescu, A.B.3
  • 20
    • 42349094538 scopus 로고    scopus 로고
    • Meta-analysis of two genome-wide association studies of bipolar disorder reveals important points of agreement
    • Baum AE, Hamshere M, Green E, Cichon S, Rietschel M, Noethen MM, et al. Meta-analysis of two genome-wide association studies of bipolar disorder reveals important points of agreement. Mol Psychiatry 2008; 13: 466-7.
    • (2008) Mol Psychiatry , vol.13 , pp. 466-467
    • Baum, A.E.1    Hamshere, M.2    Green, E.3    Cichon, S.4    Rietschel, M.5    Noethen, M.M.6
  • 21
    • 50449089356 scopus 로고    scopus 로고
    • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
    • Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, et al. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 2008; 40: 1056-8.
    • (2008) Nat Genet , vol.40 , pp. 1056-1058
    • Ferreira, M.A.1    O'Donovan, M.C.2    Meng, Y.A.3    Jones, I.R.4    Ruderfer, D.M.5    Jones, L.6
  • 22
    • 21844435448 scopus 로고    scopus 로고
    • Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population
    • Thomson PA, Wray NR, Millar JK, Evans KL, Hellard SL, Condie A, et al. Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Mol Psychiatry 2005; 10: 657-68.
    • (2005) Mol Psychiatry , vol.10 , pp. 657-668
    • Thomson, P.A.1    Wray, N.R.2    Millar, J.K.3    Evans, K.L.4    Hellard, S.L.5    Condie, A.6
  • 23
    • 77957923276 scopus 로고    scopus 로고
    • Novel association strategy with copy number variation for identifying new risk Loci of human diseases
    • Chen X, Li X, Wang P, Liu Y, Zhang Z, Zhao G, et al. Novel association strategy with copy number variation for identifying new risk Loci of human diseases. PloS One 2010; 5: 1-10.
    • (2010) PloS One , vol.5 , pp. 1-10
    • Chen, X.1    Li, X.2    Wang, P.3    Liu, Y.4    Zhang, Z.5    Zhao, G.6
  • 25
    • 67349209853 scopus 로고    scopus 로고
    • Next-generation DNA sequencing techniques
    • Ansorge WJ. Next-generation DNA sequencing techniques. N Biotechnol 2009; 25: 195-203.
    • (2009) N Biotechnol , vol.25 , pp. 195-203
    • Ansorge, W.J.1
  • 26
    • 45749158144 scopus 로고    scopus 로고
    • Psychiatric genetics: Progress amid controversy
    • Burmeister M, McInnis MG, Zollner S. Psychiatric genetics: progress amid controversy. Nat Rev Genet 2008; 9: 527-40.
    • (2008) Nat Rev Genet , vol.9 , pp. 527-540
    • Burmeister, M.1    McInnis, M.G.2    Zollner, S.3
  • 29
    • 77955299096 scopus 로고    scopus 로고
    • High-resolution analysis of parent-of-origin allelic expression in the mouse brain
    • Gregg C, Zhang J, Weissbourd B, Luo S, Schroth GP, Haig D, et al. High-resolution analysis of parent-of-origin allelic expression in the mouse brain. Science 2010; 329: 643-8.
    • (2010) Science , vol.329 , pp. 643-648
    • Gregg, C.1    Zhang, J.2    Weissbourd, B.3    Luo, S.4    Schroth, G.P.5    Haig, D.6
  • 30
    • 77952574649 scopus 로고    scopus 로고
    • MicroRNA dysregulation in psychiatric disease
    • Miller BH, Wahlestedt C. MicroRNA dysregulation in psychiatric disease. Brain Res 2010; 1338: 89-99.
    • (2010) Brain Res , vol.1338 , pp. 89-99
    • Miller, B.H.1    Wahlestedt, C.2
  • 31
    • 54149095553 scopus 로고    scopus 로고
    • Biological principles of microRNA-mediated regulation: Shared themes amid diversity
    • Flynt AS, Lai EC. Biological principles of microRNA-mediated regulation: shared themes amid diversity. Nat Rev Genet 2008; 9: 831-42.
    • (2008) Nat Rev Genet , vol.9 , pp. 831-842
    • Flynt, A.S.1    Lai, E.C.2
  • 32
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 33
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 2010; 11: 597-610.
    • (2010) Nat Rev Genet , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 34
    • 33644768174 scopus 로고    scopus 로고
    • Control of translation and mRNA degradation by miRNAs and siRNAs
    • Valencia-Sánchez MA, Liu J, Hannon GJ, Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev 2006; 20: 515-24.
    • (2006) Genes Dev , vol.20 , pp. 515-524
    • Valencia-Sánchez, M.A.1    Liu, J.2    Hannon, G.J.3    Parker, R.4
  • 35
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature 2004; 431: 350-5.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 36
    • 49649104486 scopus 로고    scopus 로고
    • MicroRNAs in brain function and disease
    • Kuss AW, Chen W. MicroRNAs in brain function and disease. Curr Neurol Neurosci Rep 2008; 8: 190-7.
    • (2008) Curr Neurol Neurosci Rep , vol.8 , pp. 190-197
    • Kuss, A.W.1    Chen, W.2
  • 38
    • 33751254116 scopus 로고    scopus 로고
    • The neuronal microRNA system
    • Kosik KS. The neuronal microRNA system. Nat Rev Neurosci 2006; 7: 911-20.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 911-920
    • Kosik, K.S.1
  • 39
    • 78650847643 scopus 로고    scopus 로고
    • Circulating miRNA signatures: Promising prognostic tools for cancer
    • Heneghan HM, Miller N, Kerin MJ. Circulating miRNA signatures: promising prognostic tools for cancer. J Clin Oncol 2010; 28: 573-4.
    • (2010) J Clin Oncol , vol.28 , pp. 573-574
    • Heneghan, H.M.1    Miller, N.2    Kerin, M.J.3
  • 40
    • 67349273027 scopus 로고    scopus 로고
    • MicroRNA in autoimmunity and autoimmune diseases
    • Pauley KM, Cha S, Chan EK. MicroRNA in autoimmunity and autoimmune diseases. J Autoimmun 2009; 32: 189-94.
    • (2009) J Autoimmun , vol.32 , pp. 189-194
    • Pauley, K.M.1    Cha, S.2    Chan, E.K.3
  • 41
    • 77956378275 scopus 로고    scopus 로고
    • Expression of miR-146a/b is associated with the Toll-like receptor 4 signal in coronary artery disease: Effect of renin-angiotensin system blockade and statins on miRNA-146a/b and Toll-like receptor 4 levels
    • (Lond)
    • Takahashi Y, Satoh M, Minami Y, Tabuchi T, Itoh T, Nakamura M. Expression of miR-146a/b is associated with the Toll-like receptor 4 signal in coronary artery disease: effect of renin-angiotensin system blockade and statins on miRNA-146a/b and Toll-like receptor 4 levels. Clin Sci (Lond) 2010; 119: 395-405.
    • (2010) Clin Sci , vol.119 , pp. 395-405
    • Takahashi, Y.1    Satoh, M.2    Minami, Y.3    Tabuchi, T.4    Itoh, T.5    Nakamura, M.6
  • 42
    • 79952216572 scopus 로고    scopus 로고
    • Los niveles de expresión de los receptores toll-like 2 y 4 en neutrófilos se asocian con el pronóstico de los pacientes con ictus isquémico
    • Brea D, Blanco M, Sobrino T, Ramos-Cabrer P, Castillo J. Los niveles de expresión de los receptores toll-like 2 y 4 en neutrófilos se asocian con el pronóstico de los pacientes con ictus isquémico. Rev Neurol 2011; 52: 12-9.
    • (2011) Rev Neurol , vol.52 , pp. 12-19
    • Brea, D.1    Blanco, M.2    Sobrino, T.3    Ramos-Cabrer, P.4    Castillo, J.5
  • 44
    • 49749147199 scopus 로고    scopus 로고
    • MicroRNA function in neuronal development, plasticity and disease
    • Fiore R, Siegel G, Schratt G. MicroRNA function in neuronal development, plasticity and disease. Biochim Biophys Acta 2008; 1779: 471-8.
    • (2008) Biochim Biophys Acta , vol.1779 , pp. 471-478
    • Fiore, R.1    Siegel, G.2    Schratt, G.3
  • 45
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 2004; 5: 13.
    • (2004) Genome Biol , vol.5 , pp. 13
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 46
    • 78249275505 scopus 로고    scopus 로고
    • MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders
    • Kim AH, Reimers M, Maher B, Williamson V, McMichael O, McClay JL, et al. MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders. Schizophr Res 2010; 124: 183-91.
    • (2010) Schizophr Res , vol.124 , pp. 183-191
    • Kim, A.H.1    Reimers, M.2    Maher, B.3    Williamson, V.4    McMichael, O.5    McClay, J.L.6
  • 48
    • 70450248489 scopus 로고    scopus 로고
    • MicroRNAs at the synapse
    • Schratt G. MicroRNAs at the synapse. Nat Rev Neurosci 2009; 10: 842-9.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 842-849
    • Schratt, G.1
  • 50
    • 77956997715 scopus 로고    scopus 로고
    • Mechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disorders
    • Lin YC, Koleske AJ. Mechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disorders. Annu Rev Neurosci 2010; 33: 349-78.
    • (2010) Annu Rev Neurosci , vol.33 , pp. 349-378
    • Lin, Y.C.1    Koleske, A.J.2
  • 52
    • 64949159019 scopus 로고    scopus 로고
    • Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers
    • Zhou R, Yuan P, Wang Y, Hunsberger JG, Elkahloun A, Wei Y, et al. Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers. Neuropsychopharmacology 2009; 34: 1395-405.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1395-1405
    • Zhou, R.1    Yuan, P.2    Wang, Y.3    Hunsberger, J.G.4    Elkahloun, A.5    Wei, Y.6
  • 53
  • 55
    • 75949101467 scopus 로고    scopus 로고
    • Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132
    • Edbauer D, Neilson JR, Foster KA, Wang CF, Seeburg DP, Batterton MN, et al. Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron 2010; 65: 373-84.
    • (2010) Neuron , vol.65 , pp. 373-384
    • Edbauer, D.1    Neilson, J.R.2    Foster, K.A.3    Wang, C.F.4    Seeburg, D.P.5    Batterton, M.N.6
  • 56
    • 1642540373 scopus 로고    scopus 로고
    • Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
    • Jin P, Zarnescu DC, Ceman S, Nakamoto M, Mowrey J, Jongens TA, et al. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci 2004; 7: 113-7.
    • (2004) Nat Neurosci , vol.7 , pp. 113-117
    • Jin, P.1    Zarnescu, D.C.2    Ceman, S.3    Nakamoto, M.4    Mowrey, J.5    Jongens, T.A.6
  • 57
    • 33845429380 scopus 로고    scopus 로고
    • Inositol monophosphatase regulates localization of synaptic components and behavior in the mature nervous system of C. elegans
    • Tanizawa Y, Kuhara A, Inada H, Kodama E, Mizuno T, Mori I. Inositol monophosphatase regulates localization of synaptic components and behavior in the mature nervous system of C. elegans. Genes Dev 2006; 20: 3296-310.
    • (2006) Genes Dev , vol.20 , pp. 3296-3310
    • Tanizawa, Y.1    Kuhara, A.2    Inada, H.3    Kodama, E.4    Mizuno, T.5    Mori, I.6
  • 58
    • 48249084896 scopus 로고    scopus 로고
    • The mood stabilizer valproate inhibits both inositol-and diacylglycerol-signaling pathways in Caenorhabditis elegans
    • Tokuoka SM, Saiardi A, Nurrish SJ. The mood stabilizer valproate inhibits both inositol-and diacylglycerol-signaling pathways in Caenorhabditis elegans. Mol Biol Cell 2008; 19: 2241-50.
    • (2008) Mol Biol Cell , vol.19 , pp. 2241-2250
    • Tokuoka, S.M.1    Saiardi, A.2    Nurrish, S.J.3
  • 59
    • 36549029252 scopus 로고    scopus 로고
    • Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder
    • Schloesser RJ, Huang J, Klein PS, Manji HK. Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology 2008; 33: 110-33.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 110-133
    • Schloesser, R.J.1    Huang, J.2    Klein, P.S.3    Manji, H.K.4
  • 60
    • 77952584927 scopus 로고    scopus 로고
    • RNAi therapeutics for CNS disorders
    • Boudreau RL, Davidson BL. RNAi therapeutics for CNS disorders. Brain Res 2010; 1338: 112-21.
    • (2010) Brain Res , vol.1338 , pp. 112-121
    • Boudreau, R.L.1    Davidson, B.L.2


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