How dynein and microtubules rotate the nucleus

Journal of Cellular Physiology

Volumn 226, Issue 10, 2011, Pages 2666-2674

  Wu, Jun ^a   Lee, Kristen C ^b   Dickinson, Richard B ^a   Lele, Tanmay P ^a  

^a J Crayton Pruitt Family Department of Biomedical Engineering   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE;

ARTICLE; CELL ACTIVITY; CELL NUCLEUS; CENTROSOME; CONTROLLED STUDY; MICROTUBULE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NUCLEAR ROTATION ANGLE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TENSION; TORQUE;

ANIMALS; BIOMECHANICS; CELL NUCLEUS; CENTROSOME; COMPUTER SIMULATION; CYTOPLASMIC DYNEINS; FLUORESCENT DYES; LUMINESCENT PROTEINS; MICE; MICROTUBULES; MODELS, BIOLOGICAL; NIH 3T3 CELLS; ROTATION; TORQUE;

EID: 79960679617     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22616     Document Type: Article

References (37)

1. Albrecht-Buehler G. 1984. Movement of nucleus and centrosphere in 3T3 cells. In: Levine AJ, Woude GFV, Toop WC, Watson JD, editors. Cancer cells: The transformed phenotype. New York: Cold Spring Harbor Laboratory. pp 87-96.
2. Allen VW, Kropf DL. 1992. Nuclear rotation and lineage specification in Pelvetia embryos. Development 115, 873-883.
3. Brock AL, Ingber DE. 2005. Control of the direction of lamellipodia extension through changes in the balance between Rac and Rho activities. Mol Cell Biomech 2: 135-143.
4. Burakov A, Nadezhdina E, Slepchenko B, Rodionov V. 2003. Centrosome positioning in interphase cells. J Cell Biol 162: 963-969.
5. Chancellor TJ, Lee J, Thodeti CK, Lele T. 2010. Actomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation. Biophys J 99(1): 115-123.
6. Evans E. 2001. Probing the relation between force-lifetime-and chemistry in single molecular bonds. Annu Rev Biophys Biomol Struct 30: 105-128.
7. Fink J, Thery M, Azioune A, Dupont R, Chatelain F, Bornens M, Piel M. 2007. Comparative study and improvement of current cell micro-patterning techniques. Lab Chip 7: 672-680.
8. Fridolfsson HN, Ly N, Meyerzon M, Starr DA. 2010. UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Dev Biol 338: 237-250.
9. Gennerich A, Carter AP, Reck-Peterson SL, Vale RD. 2007. Force-induced bidirectional stepping of cytoplasmic dynein. Cell 131: 952-965.
10. Gerashchenko MV, Chernoivanenko IS, Moldaver MV, Minin AA. 2009. Dynein is a motor for nuclear rotation while vimentin IFs is a "brake." Cell Biol Int 33: 1057-1064.
11. Gliksman NR, Skibbens RV, Salmon ED. 1993. How the transition frequencies of microtubule dynamic instability (nucleation, catastrophe, and rescue) regulate microtubule dynamics in interphase and mitosis: Analysis using a Monte Carlo computer simulation. Mol Biol Cell 4: 1035-1050.
12. Gomes ER, Jani S, Gundersen GG. 2005. Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. Cell 121: 451-463.
13. Gros-Louis F, Dupre N, Dion P, Fox MA, Laurent S, Verreault S, Sanes JR, Bouchard JP, Rouleau GA. 2007. Mutations in SYNE1 lead to a newly discovered form of autosomal recessive cerebellar ataxia. Nat Genet 39: 80-85.
14. Howard J. 2006. Elastic and damping forces generated by confined arrays of dynamic microtubules. Phys Biol 3: 54-66.
15. Jaalouk DE, Lammerding J. 2009. Mechanotransduction gone awry. Nat Rev Mol Cell Biol 10: 63-73.
16. Ji JY, Lee RT, Vergnes L, Fong LG, Stewart CL, Reue K, Young SG, Zhang Q, Shanahan CM, Lammerding J. 2007. Cell nuclei spin in the absence of lamin b1. J Biol Chem 282: 20015-20026.
17. Khatau SB, Hale CM, Stewart-Hutchinson PJ, Patel MS, Stewart CL, Searson PC, Hodzic D, Wirtz D. 2009. A perinuclear actin cap regulates nuclear shape. Proc Natl Acad Sci USA 106: 19017-19022.
18. King SJ, Brown CL, Maier KC, Quintyne NJ, Schroer TA. 2003. Analysis of the dynein-dynactin interaction in vitro and in vivo. Mol Biol Cell 14: 5089-5097.
19. Lee JS, Chang MI, Tseng Y, Wirtz D. 2005. Cdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under mechanical shear stress. Mol Biol Cell 16: 871-880.
20. Levy JR, Holzbaur EL. 2008. Dynein drives nuclear rotation during forward progression of motile fibroblasts. J Cell Sci 121: 3187-3195.
21. Morris NR. 2003. Nuclear positioning: The means is at the ends. Curr Opin Cell Biol 15: 54-59.
22. Paddock SW, Albrecht-Buehler G. 1988. Rigidity of the nucleus during nuclear rotation in 3T3 cells. Exp Cell Res 175: 409-413.
23. Parker KK, Brock AL, Brangwynne C, Mannix RJ, Wang N, Ostuni E, Geisse NA, Adams JC, Whitesides GM, Ingber DE. 2002. Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces. FASEB J 16: 1195-1204.
24. Pomerat CM. 1953. Rotating nuclei in tissue cultures of adult human nasal mucosa. Exp Cell Res 5: 191-196.
25. Quintyne NJ, Gill SR, Eckley DM, Crego CL, Compton DA, Schroer TA. 1999. Dynactin is required for microtubule anchoring at centrosomes. J Cell Biol 147: 321-334.
26. Russell RJ, Xia SL, Dickinson RB, Lele TP. 2009. Sarcomere mechanics in capillary endothelial cells. Biophys J 97: 1578-1585.
27. Shelden E, Wadsworth P. 1993. Observation and quantification of individual microtubule behavior in vivo: Microtubule dynamics are cell-type specific. J Cell Biol 120: 935-945.
28. Starr DA. 2009. A nuclear-envelope bridge positions nuclei and moves chromosomes. J Cell Sci 122: 577-586.
29. Thery M, Racine V, Piel M, Pepin A, Dimitrov A, Chen Y, Sibarita JB, Bornens M. 2006. Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity. Proc Natl Acad Sci USA 103: 19771-19776.
30. Toba S, Watanabe TM, Yamaguchi-Okimoto L, Toyoshima YY, Higuchi H. 2006. Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein. Proc Natl Acad Sci USA 103: 5741-5745.
31. Vogel SK, Pavin N, Maghelli N, Julicher F, Tolic-Norrelykke IM. 2009. Self-organization of dynein motors generates meiotic nuclear oscillations. PLoS Biol 7: e1000087.
32. Wang N, Tytell JD, Ingber DE. 2009. Mechanotransduction at a distance: Mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol 10: 75-82.
33. Warren DT, Zhang Q, Weissberg PL, Shanahan CM. 2005. Nesprins: Intracellular scaffolds that maintain cell architecture and coordinate cell function? Expert Rev Mol Med 7: 1-15.
34. Yamada M, Toba S, Takitoh T, Yoshida Y, Mori D, Nakamura T, Iwane AH, Yanagida T, Imai H, Yu-Lee LY, Schroer T, Wynshaw-Boris A, Hirotsune S. 2010. mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1. EMBO J 29: 517-531.
35. Yao KT, Ellingson DJ. 1969. Observations on nuclear rotation and oscillation in Chinese hamster germinal cells in vitro. Exp Cell Res 55: 39-42.
36. Zhang X, Xu R, Zhu B, Yang X, Ding X, Duan S, Xu T, Zhuang Y, Han M. 2007. Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation. Development 134: 901-908.
37. Zhou K, Rolls MM, Hall DH, Malone CJ, Hanna-Rose W. 2009. A ZYG-12-dynein interaction at the nuclear envelope defines cytoskeletal architecture in the C. elegans gonad. J Cell Biol 186: 229-241.