Sulfated glycosaminoglycans are required for specific and sensitive Fibroblast Growth Factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho

Journal of Biological Chemistry

Volumn 286, Issue 30, 2011, Pages 26418-26423

  Nakamura, Masao ^a,b   Uehara, Yuriko ^a   Asada, Masahiro ^a   Honda, Emi ^a   Nagai, Naoko ^c   Kimata, Koji ^c   Suzuki, Masashi ^a,b   Imamura, Toru ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b IBARAKI UNIVERSITY   (Japan)

^c AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHONDROITIN SULFATES; CO-PRESENCE; FGF RECEPTORS; FIBROBLAST GROWTH FACTOR; HEPARAN SULFATES; HUMAN FIBROBLAST; NANOMOLAR LEVELS; PHYSIOLOGICAL CONCENTRATIONS; PICOMOLAR LEVELS; SULFATED GLYCOSAMINOGLYCANS;

CELL CULTURE; FIBROBLASTS; PEPTIDES; POLYSACCHARIDES;

SIGNALING;

BETA KLOTHO PROTEIN; CHONDROITIN SULFATE; FIBROBLAST GROWTH FACTOR 19; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR 4; HEPARAN SULFATE; HEPARIN; KLOTHO PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; LIVER; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN ISOLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CATTLE; CELL LINE; FIBROBLAST GROWTH FACTORS; GLYCOSAMINOGLYCANS; HUMANS; LIVER; MEMBRANE PROTEINS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 4; SIGNAL TRANSDUCTION;

EID: 79960677449     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.251140     Document Type: Article

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