Barx1-Mediated inhibition of Wnt signaling in the mouse thoracic foregut controls Tracheo-Esophageal septation and epithelial differentiation

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Woo, Janghee ^a,b   Miletich, Isabelle ^c   Kim, Byeong Moo ^a   Sharpe, Paul T ^c   Shivdasani, Ramesh A ^a,d  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD UNIVERSITY   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; HOMEODOMAIN PROTEIN; PROTEIN BARX1; UNCLASSIFIED DRUG; WNT PROTEIN; BARX1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FOREGUT DEVELOPMENT; MALE; MOUSE; MOUSE EMBRYO; NONHUMAN; ORGANOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; ENDODERM; EPITHELIUM CELL; ESOPHAGUS; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; HISTOLOGY; MESODERM; METABOLISM; PRENATAL DEVELOPMENT; THORAX; TRACHEA;

ANIMALIA; FISTULA; VERTEBRATA;

ANIMALS; CELL DIFFERENTIATION; ENDODERM; EPITHELIAL CELLS; ESOPHAGUS; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MALE; MESODERM; MICE; SIGNAL TRANSDUCTION; THORAX; TRACHEA; TRANSCRIPTION FACTORS; WNT PROTEINS;

EID: 79960669901     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022493     Document Type: Article

References (23)

1. Kaufman MH, (1992) The atlas of mouse development. London Academic Press.
2. Que J, Choi M, Ziel JW, Klingensmith J, Hogan BL, (2006) Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps. Differentiation 74: 422-437.
3. Kim BM, Buchner G, Miletich I, Sharpe PT, Shivdasani RA, (2005) The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling. Dev Cell 8: 611-622.
4. Morrisey EE, Hogan BL, (2010) Preparing for the first breath: genetic and cellular mechanisms in lung development. Dev Cell 18: 8-23.
5. Que J, Luo X, Schwartz RJ, Hogan BL, (2009) Multiple roles for Sox2 in the developing and adult mouse trachea. Development 136: 1899-1907.
6. Brunner HG, van Bokhoven H, (2005) Genetic players in esophageal atresia and tracheoesophageal fistula. Curr Opin Genet Dev 15: 341-347.
7. Goss AM, Tian Y, Tsukiyama T, Cohen ED, Zhou D, et al. (2009) Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell 17: 290-298.
8. Harris-Johnson KS, Domyan ET, Vezina CM, Sun X, (2009) beta-Catenin promotes respiratory progenitor identity in mouse foregut. Proc Natl Acad Sci U S A 106: 16287-16292.
9. Tissier-Seta JP, Mucchielli ML, Mark M, Mattei MG, Goridis C, et al. (1995) Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach. Mech Dev 51: 3-15.
10. Kim BM, Miletich I, Mao J, McMahon AP, Sharpe PA, et al. (2007) Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development 134: 3603-3613.
11. Minoo P, Hamdan H, Bu D, Warburton D, Stepanik P, et al. (1995) TTF-1 regulates lung epithelial morphogenesis. Dev Biol 172: 694-698.
12. Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, et al. (2007) Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development 134: 2521-2531.
13. Senoo M, Pinto F, Crum CP, McKeon F, (2007) p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 129: 523-536.
14. Yu HM, Jerchow B, Sheu TJ, Liu B, Costantini F, et al. (2005) The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development 132: 1995-2005.
15. DasGupta R, Fuchs E, (1999) Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 126: 4557-4568.
16. Litingtung Y, Lei L, Westphal H, Chiang C, (1998) Sonic hedgehog is essential to foregut development. Nat Genet 20: 58-61.
17. Motoyama J, Liu J, Mo R, Ding Q, Post M, et al. (1998) Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Nat Genet 20: 54-57.
18. De Moerlooze L, Spencer-Dene B, Revest JM, Hajihosseini M, Rosewell I, et al. (2000) An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development 127: 483-492.
19. Sekine K, Ohuchi H, Fujiwara M, Yamasaki M, Yoshizawa T, et al. (1999) Fgf10 is essential for limb and lung formation. Nat Genet 21: 138-141.
20. Li Y, Litingtung Y, Ten Dijke P, Chiang C, (2007) Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresia. Dev Dyn 236: 746-754.
21. Rodriguez P, Da Silva S, Oxburgh L, Wang F, Hogan BL, et al. (4171-4176).
22. Mitsiadis TA, Angeli I, James C, Lendahl U, Sharpe PT, (2003) Role of Islet1 in the patterning of murine dentition. Development 130: 4451-4460.
23. Tucker AS, Matthews KL, Sharpe PT, (1998) Transformation of tooth type induced by inhibition of BMP signaling. Science 282: 1136-1138.