Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growth

Respiratory Research

Volumn 12, Issue , 2011, Pages

  Lin, Miao ^a   Chamoto, Kenji ^a   Gibney, Barry C ^a   Lee, Grace S ^a   Collings Simpson, Dinee ^a   Houdek, Jan ^b   Konerding, Moritz A ^b   Tsuda, Akira ^c   Mentzer, Steven J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; COL18A1 PROTEIN; COL4A3 PROTEIN; CSF3 PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPIDERMAL GROWTH FACTOR; EREG PROTEIN; F2 PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; KERATINOCYTE GROWTH FACTOR; LECT1 PROTEIN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN; SCATTER FACTOR; SPHINGOSINE KINASE 1; UNCLASSIFIED DRUG; VASCULOTROPIN A; MESSENGER RNA;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SELECTION; CLUSTER ANALYSIS; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME DEGRADATION; FLOW CYTOMETRY; GENE EXPRESSION; GENE INTERACTION; GENETIC TRANSCRIPTION; LUNG GROWTH; LUNG RESECTION; LUNG VOLUME; MALE; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; THORACOTOMY; TISSUE GROWTH; ANIMAL; C57BL MOUSE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; LUNG; METABOLISM; METHODOLOGY; POLYMERASE CHAIN REACTION; REGENERATION; TIME; VASCULARIZATION;

ANIMALS; ANTIGENS, CD31; CLUSTER ANALYSIS; ENDOTHELIAL CELLS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; LUNG; MALE; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; PNEUMONECTOMY; POLYMERASE CHAIN REACTION; REGENERATION; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 79960669891     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-12-98     Document Type: Article

References (58)

1. Degraff AC, Grover RF, Johnson RL, Hammond JW, Miller JM. Diffusing capacity of lung in caucasians native to 3,100 m. J Appl Physiol 1970, 29(1):71-76.
2. Hopkins N, McLoughlin P. The structural basis of pulmonary hypertension in chronic lung disease: remodelling, rarefaction or angiogenesis?. J Anat 2002, 201(4):335-348. 10.1046/j.1469-7580.2002.00096.x, 1570922, 12430958.
3. Schraufnagel DE. Monocrotaline-induced angiogenesis. Differences in the bronchial and pulmonary vasculature. Am J Pathol 1990, 137(5):1083-1090. 1877663, 1700616.
4. Ravnic DJ, Konerding MA, Pratt JP, Wolloscheck T, Huss HT, Mentzer SJ. The murine bronchopulmonary microcirculation in hapten-induced inflammation. J Thorac Cardiovasc Surg 2007, 133:97-103. 10.1016/j.jtcvs.2006.08.054, 17198790.
5. Grover RF, Wagner WW, McMurtry IF, Reeves JT. Pulmonary circulation. Handbook of Physiology The Cardiovascular System, Peripheral Circulation and Organ Blood Flow 1983, 3:103-136. Bethesda: Am. Physiol. Soc.
6. Schraufnagel DE, Malik R, Goel V, Ohara N, Chang SW. Lung capillary changes in hepatic cirrhosis in rats. Am J Physiol-Lung Cell Mol Physiol 1997, 272(1):L139-L147.
7. Hopkins N, Cadogan E, Giles S, McLoughlin P. Chronic airway infection leads to angiogenesis in the pulmonary circulation. J Appl Physiol 2001, 91(2):919-928.
8. Nannmark U, Johansson BR, Bryant JL, Unger ML, Hokland ME, Goldfarb RH, Basse PH. Microvessel origin and distribution in pulmonary metastases of B16 melanoma: implication for adoptive immunotherapy. Cancer Res 1995, 55(20):4627-4632.
9. Hsia CCW, Herazo LF, Fryderdoffey F, Weibel ER. Compensatory lung growth occurs in adult dogs after right pneumonectomy. J Clin Investig 1994, 94(1):405-412. 10.1172/JCI117337, 296323, 8040282.
10. Addis T. Compensatory hypertrophy of the lung after unilateral pneumectomy. J Exp Med 1928, 47(1):51-56. 2131336, 19869400.
11. Brody JS, Burki R, Kaplan N. Deoxyribonucleic-acid synthesis in lung-cells during compensatory lung growth after pneumonectomy. Am Rev Respir Dis 1978, 117(2):307-316.
12. Heuer GJ, Dunn GR. Experimental pneumectomy. Bull Johns Hopkins Hosp 1920, 31:31-42.
13. Fehrenbach H, Voswinickel R, Michl V, Mehling T, Fehrenbach A, Seeger W, Nyengaard JR. Neoalveolarisation contributes to compensatory lung growth following pneumonectomy in mice. Eur Respir J 2008, 31(3):515-522. 10.1183/09031936.00109407, 18032439.
14. Muhlfeld C, Weibel ER, Hahn U, Kummer W, Nyengaard JR, Ochs M. Is Length an Appropriate Estimator to Characterize Pulmonary Alveolar Capillaries? A Critical Evaluation in the Human Lung. Anat Rec 2010, 293(7):1270-1275.
15. Landesberg LJ, Ramalingam R, Lee K, Rosengart TK, Crystal RG. Upregulation of transcription factors in lung in the early phase of postpneumonectomy lung growth. Am J Physiol Lung Cell Mol Physiol 2001, 281(5):L1138-1149.
16. Kaza AK, Kron IL, Leuwerke SM, Tribble CG, Laubach VE. Keratinocyte growth factor enhances post-pneumonectomy lung growth by alveolar proliferation. Circulation 2002, 106:I120-I124.
17. Sakamaki Y, Matsumoto K, Mizuno S, Miyoshi S, Matsuda H, Nakamura T. Hepatocyte growth factor stimulates proliferation of respiratory epithelial cells during postpneumonectomy compensatory lung growth in mice. Am J Respir Cell Mol Biol 2002, 26(5):525-533.
18. Zhang Q, Bellotto DJ, Ravikumar P, Moe OW, Hogg RT, Hogg DC, Estrera AS, Johnson RL, Hsia CC. Postpneumonectomy lung expansion elicits hypoxia-inducible factor-1alpha signaling. Am J Physiol Lung Cell Mol Physiol 2007, 293(2):L497-504. 10.1152/ajplung.00393.2006, 17513452.
19. Leuwerke SM, Kaza AK, Tribble CG, Kron IL, Laubach VE. Inhibition of compensatory lung growth in endothelial nitric oxide synthase-deficient mice. Am J Physiol Lung Cell Mol Physiol 2002, 282(6):L1272-1278.
20. Yuan SZ, Hannam V, Belcastro R, Cartel N, Cabacungan J, Wang JX, Diambomba Y, Johnstone L, Post M, Tanswell AK. A role for platelet-derived growth factor-BB in rat postpneumonectomy compensatory lung growth. Pediatr Res 2002, 52(1):25-33. 10.1203/00006450-200207000-00007, 12084843.
21. Jancelewicz T, Grethel EJ, Chapin CJ, Clifton MS, Nobuhara KK. Vascular Endothelial Growth Factor Isoform and Receptor Expression During Compensatory Lung Growth. J Surg Res 2008, 160(1):107-113.
22. Paxson JA, Parkin CD, Iyer LK, Mazan MR, Ingenito EP, Hoffman AM. Global gene expression patterns in the post-pneumonectomy lung of adult mice. Respir Res 2009, 10(92):1-15. 2626579, 19134192.
23. Wolff JC, Wilhelm J, Fink L, Seeger W, Voswinckel R. Comparative gene expression profiling of post-natal and post-pneumonectomy lung growth. Eur Respir J 2010, 35(3):655-666. 10.1183/09031936.00059709, 19717484.
24. Gibney B, Lee GS, Houdek J, Lin M, Chamoto K, Konerding MA, Tsuda A, Mentzer SJ. Dynamic determination of oxygenation and lung compliance in murine pneumonectomy. Exp Lung Res 2011, 37:301-309. 10.3109/01902148.2011.561399, 21574875.
25. Abdi K, Rogers RA, Li X, Lopez P, Rawn J, Mentzer SJ. In situ fluorescence labeling of sheep lung microvascular endothelium. In Vitro Cell Dev Biol Anim 1995, 31(4):310-315. 10.1007/BF02634006, 7795850.
26. Shankey TV, Rabinovitch PS, Bagwell B, Bauer KD, Duque RE, Hedley DW, Mayall BH, Wheeless L. Guidelines for implementation of clinical DNA cytometry. Cytometry 1993, 14(5):472-477. 10.1002/cyto.990140503, 8354117.
27. Wersto RP, Chrest FJ, Leary JF, Morris C, Stetler-Stevenson M, Gabrielson E. Doublet discrimination in DNA cell-cycle analysis. Cytometry 2001, 46(5):296-306. 10.1002/cyto.1171, 11746105.
28. Baldwin HS, Shen HM, Yan HC, DeLisser HM, Chung A, Mickanin C, Trask T, Kirschbaum NE, Newman PJ, Albelda SM, et al. Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): Alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development 1994, 120:2539-2553.
29. Springer T, Galfre G, Secher DS, Milstein C. MAC-1 - a macrophage differentiation antigen identified by monoclonal antibody. Eur J Immunol 1979, 9(4):301-306. 10.1002/eji.1830090410, 89034.
30. Ledbetter JA, Herzenberg LA. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol Rev 1979, 47:63-90. 10.1111/j.1600-065X.1979.tb00289.x, 398327.
31. Su M, He C, West CA, Mentzer SJ. Cytolytic peptides induce biphasic permeability changes in mammalian cell membranes. JImmunolMethods 2001, 252(1-2):63-71.
32. Schroeder A, Mueller O, Stocker S, Salowsky R, Leiber M, Gassmann M, Lightfoot S, Menzel W, Granzow M, Ragg T. The RIN: an RNA integrity number for assigning integrity values to RNA measurements. BMC Mol Biol 2006, 7:1-14. 10.1186/1471-2199-7-1, 1382243, 16412221.
33. Kendziorski C, Irizarry RA, Chen KS, Haag JD, Gould MN. On the utility of pooling biological samples in microarray experiments. Proc Natl Acad Sci USA 2005, 102(12):4252-4257. 10.1073/pnas.0500607102, 552978, 15755808.
34. Stolovitzky G, Cecchi G. Efficiency of DNA replication in the polymerase chain reaction. Proc Natl Acad Sci USA 1996, 93(23):12947-12952. 10.1073/pnas.93.23.12947, 24026, 8917524.
35. Pratt JP, Zeng QT, Ravnic D, Rawn J, Huss H, Mentzer SJ. Heirarchical clustering of antibody reactivity patterns in non-human species. Cytometry 2009, 75(9):734-742. 2867243, 19639632.
36. Zeng QT, Pratt JP, Pak J, Ravnic D, Huss H, Mentzer SJ. Feature-guided clustering of multi-dimensional flow cytometry datasets. J Biomed Inform 2007, 40(3):325-331. 10.1016/j.jbi.2006.06.005, 16901761.
37. Wen XL, Fuhrman S, Michaels GS, Carr DB, Smith S, Barker JL, Somogyi R. Large-scale temporal gene expression mapping of central nervous system development. Proc Natl Acad Sci USA 1998, 95(1):334-339. 10.1073/pnas.95.1.334, 18216, 9419376.
38. Kho AT, Bhattacharya S, Mecham BH, Hong J, Kohane IS, Mariani TJ. Expression Profiles of the Mouse Lung Identify a Molecular Signature of Time-to-Birth. Am J Respir Cell Mol Biol 2009, 40(1):47-57. 2606946, 18664640.
39. Yosef N, Regev A. Impulse Control: Temporal Dynamics in Gene Transcription. Cell 2011, 144(6):886-896. 10.1016/j.cell.2011.02.015, 21414481.
40. Wells A. EGF receptor. Int J Biochem Cell Biol 1999, 31(6):637-643. 10.1016/S1357-2725(99)00015-1, 10404636.
41. Taylor DS, Cheng XB, Pawlowski JE, Wallace AR, Ferrer P, Molloy CJ. Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombin. Proc Natl Acad Sci USA 1999, 96(4):1633-1638. 10.1073/pnas.96.4.1633, 15542, 9990076.
42. Yang R, Amir J, Liu HB, Chaqour B. Mechanical strain activates a program of genes functionally involved in paracrine signaling of angiogenesis. Physiol Genomics 2008, 36(1):1-14. 10.1152/physiolgenomics.90291.2008, 2604786, 18854370.
43. Roy S, Khanna S, Rink C, Biswas S, Sen CK. Characterization of the acute temporal changes in excisional murine cutaneous wound inflammation by screening of the wound-edge transcriptome. Physiol Genomics 2008, 34(2):162-184. 10.1152/physiolgenomics.00045.2008, 2494843, 18460641.
44. Burri PH, Dbaly J, Weibel ER. Postnatal-growth of rat lung.1. Morphometry. Anat Rec 1974, 178(4):711-730. 10.1002/ar.1091780405, 4592625.
45. Caduff JH, Fischer LC, Burri PH. Scanning electron microscope study of the developing microvasculature in the postnatal rat lung. Anat Rec 1986, 216(2):154-164. 10.1002/ar.1092160207, 3777448.
46. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25(4):402-408. 10.1006/meth.2001.1262, 11846609.
47. Tsopanoglou NE, Maragoudakis ME. On the mechanism of thrombin-induced angiogenesis. Potentiation of vascular endothelial growth factor activity on endothelial cells by up-regulation of its receptors. J Biol Chem 1999, 274(34):23969-23976. 10.1074/jbc.274.34.23969, 10446165.
48. Schmitt WA, Raab RM, Stephanopoulos G. Elucidation of gene interaction networks through time-lagged correlation analysis of transcriptional data. Genome Res 2004, 14(8):1654-1663. 10.1101/gr.2439804, 509275, 15289483.
49. Segal E, Shapira M, Regev A, Pe'er D, Botstein D, Koller D, Friedman N. Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Nat Genet 2003, 34(2):166-176. 10.1038/ng1165, 12740579.
50. Csete ME, Doyle JC. Reverse engineering of biological complexity. Science 2002, 295(5560):1664-1669. 10.1126/science.1069981, 11872830.
51. Yamamoto H, Yun EJ, Gerber HP, Ferrara N, Whitsett JA, Vu TH. Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis. Dev Biol 2007, 308(1):44-53. 10.1016/j.ydbio.2007.04.042, 17583691.
52. Tokuyama W, Mikami T, Masuzawa M, Okayasu I. Autocrine and paracrine roles of VEGF/VEGFR-2 and VEGF-C/VEGFR-3 signaling in angiosarcomas of the scalp and face. Hum Pathol 2010, 41(3):407-414. 10.1016/j.humpath.2009.08.021, 19913279.
53. Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, et al. Loss of HIF-2 and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nature Medicine 2002, 8(7):702-710.
54. Gerber HP, Dixit V, Ferrara N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 1998, 273(21):13313-13316. 10.1074/jbc.273.21.13313, 9582377.
55. Olsson AK, Dimberg A, Kreuger J, Claesson-Welsh L. VEGF receptor signalling - in control of vascular function. Nat Rev Mol Cell Biol 2006, 7(5):359-371. 10.1038/nrm1911, 16633338.
56. Tabruyn SP, Griffioen AW. Molecular pathways of angiogenesis inhibition. Biochem Biophys Res Commun 2007, 355(1):1-5. 10.1016/j.bbrc.2007.01.123, 17276388.
57. Nyberg P, Xie L, Kalluri R. Endogenous inhibitors of angiogenesis. Cancer Res 2005, 65(10):3967-3979. 10.1158/0008-5472.CAN-04-2427, 15899784.
58. Maeshima Y, Sudhakar A, Lively JC, Ueki K, Kharbanda S, Kahn CR, Sonenberg N, Hynes RO, Kalluri R. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science 2002, 295(5552):140-143. 10.1126/science.1065298, 11778052.