The sterol-sensing domain (SSD) directly mediates signal-regulated endoplasmic reticulum-associated degradation (ERAD) of 3-hydroxy-3- methylglutaryl (HMG)-CoA reductase isozyme Hmg2

Journal of Biological Chemistry

Volumn 286, Issue 30, 2011, Pages 26298-26307

  Theesfeld, Chandra L ^a   Pourmand, Deeba ^a   Davis, Talib ^a   Garza, Renee M ^a   Hampton, Randolph Y ^a  

^a SECTION OF CELL AND DEVELOPMENTAL BIOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR QUALITY CONTROL; DEGRADATION PATHWAYS; ENDOPLASMIC RETICULUM; FEEDBACK REGULATION; HMG-COA REDUCTASE; MAMMALIAN COUNTERPARTS; MAMMALIAN PROTEINS; MEMBRANE PROTEINS; OXYSTEROLS; SIGNAL RECOGNITION; STEROL SENSING; STRUCTURAL CHANGE;

BIOLOGICAL MEMBRANES; DEGRADATION; FEEDBACK CONTROL; GENES; ISOENZYMES; MAMMALS; PROTEINS; QUALITY CONTROL; SIGNAL PROCESSING; YEAST;

ALCOHOLS;

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MEMBRANE PROTEIN; STEROL SENSING DOMAIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYMATIC DEGRADATION; FEEDBACK SYSTEM; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; MUTAGENESIS; NONHUMAN; PHENOTYPE; PLASTICITY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN STABILITY; QUALITY CONTROL; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; UBIQUITINATION;

ENDOPLASMIC RETICULUM; HYDROXYMETHYLGLUTARYL COA REDUCTASES; ISOENZYMES; POLYISOPRENYL PHOSPHATES; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA; MAMMALIA;

EID: 79960663655     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.244798     Document Type: Article

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