Activation of arterial matrix metalloproteinases leads to vascular calcification in chronic kidney disease

American Journal of Nephrology

Volumn 34, Issue 3, 2011, Pages 211-219

  Chen, Neal X ^a   O'Neill, Kalisha D ^a   Chen, Xianming ^a   Kiattisunthorn, Kraiwiporn ^c   Gattone, Vincent H ^a   Moe, Sharon M ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Chronic kidney disease; Gelatinase; Matrix metalloproteinase; Vascular calcification

Indexed keywords

GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL CALCIFICATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DEGRADATION; DISEASE COURSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; EXTRACELLULAR MATRIX; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE; ZYMOGRAPHY;

ANIMALS; CHRONIC DISEASE; KIDNEY DISEASES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; RATS; UP-REGULATION; VASCULAR CALCIFICATION;

EID: 79960662431     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000330175     Document Type: Article

References (20)

1. Moe SM, Chen NX: Mechanisms of vascular calcification in chronic kidney disease. J Am Soc Nephrol 2008;19:213-216. (Pubitemid 351240642)
2. Ortega N, Behonick DJ, Werb Z: Matrix remodeling during endochondral ossification. Trends Cell Biol 2004;14:86-93. (Pubitemid 38186642)
3. Lijnen HR: Metalloproteinases in development and progression of vascular disease. Pathophysiol Haemost Thromb 2003;33:275-281. (Pubitemid 40278695)
4. Back M, Ketelhuth DF, Agewall S: Matrix metalloproteinases in atherothrombosis. Prog Cardiovasc Dis 2010;52:410-428.
5. Beaudeux JL, Giral P, Bruckert E, Foglietti MJ, Chapman MJ: Matrix metalloproteinases, inflammation and atherosclerosis: therapeutic perspectives. Clin Chem Lab Med 2004;42:121-131. (Pubitemid 38401437)
6. Pawlak K, Pawlak D, Mysliwiec M: Serum matrix metalloproteinase-2 and increased oxidative stress are associated with carotid atherosclerosis in hemodialyzed patients. Atherosclerosis 2007;190:199-204. (Pubitemid 44908316)
7. Fondard O, Detaint D, Iung B, et al: Extracellular matrix remodelling in human aortic valve disease: the role of matrix metalloproteinases and their tissue inhibitors. Eur Heart J 2005;26:1333-1341. (Pubitemid 41435466)
8. Liu PY, Tsai WC, Lin CC, Hsu CH, Haung YY, Chen JH: Invasive measurements of pulse wave velocity correlate with the degree of aortic valve calcification and severity associated with matrix metalloproteinases in elderly patients with aortic valve stenosis. Clin Sci (Lond) 2004;107:415-422.
9. Qin X, Corriere MA, Matrisian LM, Guzman RJ: Matrix metalloproteinase inhibition attenuates aortic calcification. Arterioscler Thromb Vasc Biol 2006;26:1510-1516. (Pubitemid 44288976)
10. Moe SM, Seifert MF, Chen NX, et al: R-568 reduces ectopic calcification in a rat model of chronic kidney disease-mineral bone disorder (CKD-MBD). Nephrol Dial Transplant 2009;24:2371-2377.
11. Moe SM, Chen NX, Seifert MF, et al: A rat model of chronic kidney disease-mineral bone disorder. Kidney Int 2009;75:176-184.
12. El Bedoui J, Oak MH, Anglard P, Schini-Kerth VB: Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression. Cardiovasc Res 2005;67:317-325. (Pubitemid 40943625)
13. Moe SM, Duan D, Doehle BP, O'Neill KD, Chen NX: Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels. Kidney Int 2003;63:1003-1011. (Pubitemid 36315578)
14. Lomashvili KA, Cobbs S, Hennigar RA, Hardcastle KI, O'Neill WC: Phosphate-induced vascular calcification: role of pyrophosphate and osteopontin. J Am Soc Nephrol 2004;15:1392-1401. (Pubitemid 38679664)
15. Chen NX, Chen X, O'Neill KD, Atkinson SJ, Moe SM: RhoA/Rho kinase (ROCK) alters fetuin-A uptake and regulates the calcification in bovine vascular smooth muscle cells (BVSMC). Am J Physiol Renal Physiol 2010;299:F674-F680.
16. Kieffer P, Giummelly P, Schjoth B, et al: Activation of metalloproteinase-2, loss of matrix scleroprotein content and coronary artery calcification. Atherosclerosis 2001;157:251-254. (Pubitemid 32539377)
17. Basalyga DM, Simionescu DT, Xiong W, Baxter BT, Starcher BC, Vyavahare NR: Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases. Circulation 2004;110:3480-3487. (Pubitemid 39602227)
18. Chung AW, Yang HH, Kim JM, et al: Upregulation of matrix metalloproteinase-2 in the arterial vasculature contributes to stiffening and vasomotor dysfunction in patients with chronic kidney disease. Circulation 2009;120:792-801.
19. Chung AW, Yang HH, Sigrist MK, et al: Matrix metalloproteinase-2 and-9 exacerbate arterial stiffening and angiogenesis in diabetes and chronic kidney disease. Cardiovasc Res 2009;84:494-504.
20. Peiskerova M, Kalousova M, Kratochvilova M, et al: Fibroblast growth fac tor 23 and matrix metalloproteinases in patients with chronic kidney disease: are they associated with cardiovascular disease? Kidney Blood Press Res 2009;32:276-283.