The G1613A mutation in the HBV genome affects HBeAg expression and viral replication through altered core promoter activity

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Li, Man Shan ^a   LauTerrence, Terrence Chi Kong ^b   ChanSophie, Sophie Ka Ping ^a   Wong, Chi Hang ^a   NgPatrick, Patrick Kwok Shing ^a   SungJoseph, Joseph Jao Yiu ^a   ChanHenry, Henry Lik Yuen ^a   TsuiStephen, Stephen Kwok Wing ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B(E) ANTIGEN; RECOMBINANT PROTEIN; RECOMBINANT PROTEIN RFX1; UNCLASSIFIED DRUG; VIRUS DNA; DNA BINDING PROTEIN; HEPATITIS B SURFACE ANTIGEN; LUCIFERASE; REGULATORY FACTOR X TRANSCRIPTION FACTORS; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; ENZYME REPRESSION; ENZYME SYNTHESIS; FEMALE; GENE MUTATION; GENE SEQUENCE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PREVALENCE; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; VIRUS GENOME; VIRUS LOAD; VIRUS REPLICATION; WILD TYPE; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENETICS; LIVER TUMOR; METABOLISM; MUTATION; NORTHERN BLOTTING; REAL TIME POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; SOUTHERN BLOTTING; TUMOR CELL CULTURE; VIRION; VIROLOGY; WESTERN BLOTTING;

HEPATITIS B VIRUS;

BLOTTING, NORTHERN; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; DNA, VIRAL; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION, VIRAL; GENOME, VIRAL; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; LIVER NEOPLASMS; LUCIFERASES; MALE; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; VIRAL LOAD; VIRION; VIRUS REPLICATION;

EID: 79960649009     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021856     Document Type: Article

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