Lipoprotein(a)-cholesterol: A significant component of serum cholesterol

Clinica Chimica Acta

Volumn 412, Issue 19-20, 2011, Pages 1783-1787

  Kinpara, Kiyoko ^a   Okada, Hiroshi ^b   Yoneyama, Akiko ^a   Okubo, Minoru ^a,c   Murase, Toshio ^a,c  

^a TORANOMON HOSPITAL   (Japan)

^b SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^c Okinaka Memorial Institute for Medical Research   (Japan)

Author keywords

Lipoprotein(a); Lipoprotein(a) cholesterol; The Friedewald formula

Indexed keywords

CHOLESTEROL; LIPOPROTEIN A;

ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; HYPERTRIGLYCERIDEMIA; IMMUNOAFFINITY GEL ASSAY; IMMUNOASSAY; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS;

AGED; CHOLESTEROL; CHROMATOGRAPHY, AFFINITY; FEMALE; HUMANS; LIPOPROTEIN(A); MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS;

CAPRA HIRCUS;

EID: 79960646130     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2011.05.036     Document Type: Article

References (20)

1. Utermann G. Lipoprotein(a). The metabolic and molecular bases of inherited diseases 2001, 2753-2789. McGraw-Hill, NewYork. 8nd edn. C.R. Scriber, A.L. Beaudet, W.S. Aly, O. Vallo (Eds.).
2. Danesh J., Collins R., Peto R. Lipoprotein(a) and coronary heart disease: meta-analysis of prospective studies. Circulation 2000, 102:1082-1085.
3. Kamstrup P.R., Tybjærg-Hansen, Steffensen R., Nordestgaard B.G. Genetically elevated lipoprotein(a) and increased risk of myocardial infarction. JAMA 2009, 301:2331-2339.
4. Erqou S., Kaptoge, Perry P.L., et al. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA 2009, 302:412-423.
5. Nordestgaard B.G., Chapman M.J., Ray K., et al. Lipoprotein(a) as a cardiovascular risk factor: current status. Eur Heart J 2010, 31:2844-2853.
6. Berg K. A new serum type system in man: the Lp(a) system. Acta Pathol Microbiol Scand 1963, 59:362-382.
7. Scanu A.M., Fless G.M. Lipoprotein(a). Heterogeneity and biological relevance. J Clin Invest 1990, 85:1709-1715.
8. Murase T., Okubo M., Amemiya-Kudo M., et al. Impact of markedly elevated serum lipoprotein(a) concentrations (≥100mg/dl) on the risk of coronary heart disease. Metabolism 2007, 56:1187-1191.
9. Gaubatz J.W., Heideman C., Gotto A., Morrisett J.D., Dahlen G.H. Human plasma lipoprotein[a]: structural properties. J Biol Chem 1983, 256:4582-4589.
10. Fless G.M., Rolih C.A., Scanu A.M. Heterogeneity of human plasma lipoprotein (a): isolation and characterization of the lipoprotein subspecies and their apoproteins. J Biol Chem 1984, 259:11470-11476.
11. Kostner G.M., Ibovnik A., Holzer H., Grillhofer H. Preparation of a stable fresh frozen primary lipoprotein[a] (Lp[a]) standard. J Lipid Res 1999, 40:2255-2263.
12. Marcovina S.M., Albers J.J., Scanu A.M., et al. Use of a reference material proposed by the International Federation of Clinical and Laboratory Medicine to evaluate analytical methods for the determination of plasma lipoprotein(a). Clin Chem 2000, 46:1956-1967.
13. Li K.M., Wilcken D.E.L., Dudman N.P.B. Effect of serum lipoprotein(a) on estimation of low-density lipoprotein cholesterol by the Friedewald formula. Clin Chem 1994, 40:571-573.
14. Seman L.J., Jenner J.L., McNamara J.R., Schaefer E.J. Quantification of lipoprotein(a) in plasma by assaying cholesterol in lecithin-bound plasma fraction. Clin Chem 1994, 40:400-403.
15. World Health Organization Report of a WHO consultation, Part 1: diagnosis and classification of diabetes mellitus and itsu complication 1999, World Health Organization, Geneva.
16. Hiraga T., Shimada M., Okubo M., Nakanishi K., Kobayashi T., Murase T. Lipoprotein(a) is an independent risk factor for multiple cerebral infarction. Atherosclerosis 1996, 122:29-32.
17. Murase T., Okubo M., Amemiya-Kudo M., Ebara T., Mori Y. Impact of elevated serum lipoprotein (a) concentrations on the risk of coronary heart disease in patients with type 2 diabetes mellitus. Metabolism 2008, 57:791-795.
18. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502. ed.
19. Seman L.J., DeLuca C., Jenner J.L., et al. Lipoprotein(a)-cholesterol and coronary heart disease in the Framingham Heart Study. Clin Chem 1999, 45:1039-1046.
20. Clarke R., Peden J.F., Hopewell J.C., et al. Genetic variants associated with Lp(a) lipoprotein concentration and coronary disease. N Engl J Med 2009, 361:2518-2528.