Chronic haematogenous osteomyelitis in children: An unsolved problem

Journal of Bone and Joint Surgery - Series B

Volumn 93 B, Issue 8, 2011, Pages 1005-1010

  Wynn Jones, H ^a,b   Beckles, V L L ^a,c   Akinola, B ^a,d   Stevenson, A J ^a   Harrison, W J ^a  

^a Beit Cure International Hospital   (Malawi)

^b WRIGHTINGTON HOSPITAL   (United Kingdom)

^c NORTH MIDDLESEX UNIVERSITY HOSPITAL   (United Kingdom)

^d BEDFORD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BONE CEMENT; METHACRYLIC ACID METHYL ESTER;

ANEMIA; ANTIBIOTIC THERAPY; BACTEREMIA; BONE DEFECT; BONE INFECTION; BONE REMODELING; BONE TRANSPLANTATION; CD4 LYMPHOCYTE COUNT; CHILDHOOD DISEASE; CHRONIC OSTEOMYELITIS; DEBRIDEMENT; DENTAL CARE; DISEASE CLASSIFICATION; DISEASE COURSE; DISEASE PREDISPOSITION; DISEASE SEVERITY; FOLLOW UP; HEMATOGENOUS OSTEOMYELITIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYGIENE; INCIDENCE; MALARIA; MALNUTRITION; MEDICAL AUDIT; MORBIDITY; MUSCULOSKELETAL DISEASE; ORTHOPEDIC SURGERY; PEDIATRIC SURGERY; POSTOPERATIVE CARE; PREVALENCE; PRIORITY JOURNAL; REVIEW; SALMONELLOSIS; SEASONAL VARIATION; SEQUESTROTOMY; SICKLE CELL ANEMIA; SOCIAL STIGMA; SYSTEMIC THERAPY;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHRONIC DISEASE; HIV INFECTIONS; HUMANS; OSTEOMYELITIS; RISK FACTORS;

EID: 79960623654     PISSN: 0301620X     EISSN: None     Source Type: Journal    
DOI: 10.1302/0301-620X.93B8     Document Type: Review

References (47)

1. Blyth MJ, Kincaid R, Craigen MA, Bennet GC. The changing epidemiology of acute and subacute haematogenous osteomyelitis in children. J Bone Joint Surg [Br] 2001;83-B:99-102. (Pubitemid 32170970)
2. Lavy CB, Peek AC, Manjolo G. The incidence of septic arthritis in Malawian children. Int Orthop 2005;29:195-6. (Pubitemid 40922348)
3. Shaw BA, Kasser JR. Acute septic arthritis in infancy and childhood. Clin Orthop 1990;257:212-25. (Pubitemid 20246745)
4. Atijosan O, Rischewski D, Simms V, et al. A national survey of musculoskeletal impairment in Rwanda: prevalence, causes and service implications. PLoS One 2008;3:e2851.
5. Rischewski D, Kuper H, Atijosan O, et al. Poverty and musculoskeletal impairment in Rwanda. Trans R Soc Trop Med Hyg 2008;102:608-17.
6. No authors listed. Childhood under threat: the state of the world's children 2005. http://www.unicef.org/sowc05/english/Table6-E.xls (date last accessed 27 June 2011).
7. Bickler SW, Sanno-Duanda B. Epidemiology of paediatric surgical admissions to a government referral hospital in the Gambia. Bull World Health Organ 2000;78:1330-6.
8. Lavy C, Tindall A, Steinlechner C, Mkandawire N, Chimangeni S. Surgery in Malawi: a national survey of activity in rural and urban hospitals. Ann R Coll Surg Engl 2007;89:722-4. (Pubitemid 47577789)
9. Steinlechner C, Tindall A, Lavy C, Mkandawire N, Chimangeni S. A national survey of surgical activity in hospitals in Malawi. Trop Doct 2006;36:158-60. (Pubitemid 44161976)
10. Stanley CM, Rutherford GW, Morshed S, Coughlin RR, Beyeza T. Estimating the healthcare burden of osteomyelitis in Uganda. Trans R Soc Trop Med Hyg 2010;104:139-42.
11. Beckles VL, Jones HW, Harrison WJ. Chronic haematogenous osteomyelitis in children: a retrospective review of 167 patients in Malawi. J Bone Joint Surg [Br] 2010;92-B:1138-43.
12. Smith SP, Thyoka M, Lavy CB, Pitani A. Septic arthritis of the shoulder in children in Malawi: a randomised, prospective study of aspiration versus arthrotomy and washout. J Bone Joint Surg [Br] 2002;84-B:1167-72.
13. Burnett MW, Bass JW, Cook BA. Etiology of osteomyelitis complicating sickle cell disease. Pediatrics 1998;101:296-7. (Pubitemid 28076667)
14. Epps CH Jr, Bryant DD 3rd, Coles MJ, Castro O. Osteomyelitis in patients who have sickle-cell disease: diagnosis and management. J Bone Joint Surg [Am] 1991;73-A:1281-94.
15. Dormans JP, Fisher RC, Pill SG. Orthopaedics in the developing world: present and future concerns. J Am Acad Orthop Surg 2001;9:289-96.
16. Waldvogel FA, Medoff G, Swartz MN. Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects. N Engl J Med 1970;282:198-206.
17. Cierny G 3rd, Mader JT, Penninck JJ. A clinical staging system for adult osteomyelitis. Clin Orthop 2003;414:7-24.
18. Thomas DK, Sanchez P, Hoffman EB. Chronic haematogenous osteomyelitis in children. South African Orthopaedic Journal 2007;6:8-12.
19. Wynn Jones H, Harrison JW, Bates J, Evans GA, Lubega N. Radiologic classification of chronic hematogenous osteomyelitis in children. J Pediatr Orthop 2009;29:822-7.
20. Mkandawire N, Ngulube C, Lavy C. Orthopaedic clinical officer program in Malawi: a model for providing orthopaedic care. Clin Orthop 2008;466:2385-91.
21. Daoud A, Saighi-Bouaouina A. Treatment of sequestra, pseudarthroses, and defects in the long bones of children who have chronic hematogenous osteomyelitis. J Bone Joint Surg [Am] 1989;71-A:1448-68. (Pubitemid 20054461)
22. Lauschke FH, Frey CT. Hematogenous osteomyelitis in infants and children in the northwestern region of Namibia: management and two-year results. J Bone Joint Surg [Am] 1994;76-A:502-10. (Pubitemid 24154121)
23. Ascherl R, Stemberger A, Lechner F, et al. Treatment of chronic osteomyelitis with a collagen-antibiotic compound: preliminary report. Unfallchirurg 1986;12:125-7 (in German).
24. Agaja SB, Ayorinde RO. Chronic osteomyelitis in Ilorin, Nigeria. S Afr J Surg 2008;46:116-18.
25. Eyichukwu GO, Anyaehie UE. Outcome of management of chronic osteomyelitis at National Orthopaedic Hospital, Enugu. Niger J Med 2009;18:194-8.
26. Fowles JV, Lehoux J, Zlitni M, Kassab MT, Nolan B. Tibial defect due to acute haematogenous osteomyelitis: treatment and results in twenty-one children. J Bone Joint Surg [Br] 1979;61-B:77-81. (Pubitemid 10127708)
27. Langenskiöld A. Femur remodelled during growth after osteomyelitis causing coxa vara and shaft necrosis. J Pediatr Orthop 1982;2:289-94. (Pubitemid 13102003)
28. Spiegel DA, Penny JN. Chronic osteomyelitis in children. Tech in Orthop 2005;20:142-52. (Pubitemid 40800111)
29. Jain AK, Sharma DK, Kumar S, et al. Incorporation of diaphyseal sequestra in chronic haematogenous osteomyelitis. Int Orthop 1995;19:238-41.
30. Varma BP, Tuli SM, Srivastava TP, Mohindra YD. Reincorporation of early diaphyseal sequestra and bone remodelling in extensive haematogenous osteomyelitis in children. Ind J Orthop 1974;8:39-44.
31. Griffiths JC. Defects in long bones from severe neglected osteitis. J Bone Joint Surg [Br] 1968;50-B:813-21.
32. Bertram FW, Harrison J, Freeman R. The role of the periosteum in healing a large structural defect following sequestrectomy. Trop Doct 2011;41:54-60.
33. Ciampolini J, Harding KG. Pathophysiology of chronic bacterial osteomyelitis: why do antibiotics fail so often? Postgrad Med J 2000;76:479-83. (Pubitemid 30636113)
34. Meier DE, Tarpley JL, Olaolorun DA, Howard CR, Price CT. Haematogenous osteomyelitis in the developing world: a practical approach to classification and treatment with limited resources. Contemporary Orthopaedics 1993;26:495-505.
35. Bar-On E, Weigl DM, Bor N, et al. Chronic osteomyelitis in children: treatment by intramedullary reaming and antibiotic-impregnated cement rods. J Pediatr Orthop 2010;30:508-13.
36. Cho SH, Song HR, Koo KH, Jeong ST, Park YJ. Antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis. Bull Hosp Jt Dis 1997;56:140-4.
37. Alonge TO, Ogunlade SO, Omololu AB, Fashina AN, Oluwatosin A. Management of chronic osteomyelitis in a developing country using ceftriaxone-PMMA beads: an initial study. Int J Clin Pract 2002;56:181-3. (Pubitemid 34477199)
38. Grime PD, Bowerman JE, Weller PJ. Gentamicin impregnated polymethylmethacrylate (PMMA) beads in the treatment of primary chronic osteomyelitis of the mandible. Br J Oral Maxillofac Surg 1990;28:367-74.
39. Höök M, Lindberg L. Treatment of chronic osteomyelitis with gentamicin-PMMA beads: a prospective study in Nepal. Trop Doct 1987;17:157-63. (Pubitemid 17145583)
40. Mehdi M, Yahiaoui MA, Arama M, Mammeri M, Isselnane R. Local antibiotic therapy in the form of gentamycin acrylic cement beads in the treatment of chronic osteomyelitis: apropos of 87 cases. Acta Orthop Belg 1983;49:610-25 (in French).
41. Bouillet R, Bouillet B, Kadima N, Gillard J. Treatment of chronic osteomyelitis in Africa with plaster implants impregnated with antibiotics. Acta Orthop Belg 1989;55:1-11 (in French).
42. Steinlechner CW, Mkandawire NC. Non-vascularised fibular transfer in the management of defects of long bones after sequestrectomy in children. J Bone Joint Surg [Br] 2005;87-B:1259-63. (Pubitemid 41387569)
43. Ribault L. Treatment of chronic tibial osteomyelitis with total diaphyseal resection and non vascularized secondary fibular graft: a propos of 3 cases in African children. J Chir (Paris) 1991;128:22-5 (in French).
44. Zahiri CA, Zahiri H, Tehrany F. Limb salvage in advanced chronic osteomyelitis in children. Int Orthop 1997;21:249-52. (Pubitemid 27464620)
45. Kucukkaya M, Kabukcuoglu Y, Tezer M, Kuzgun U. Management of childhood chronic tibial osteomyelitis with the Ilizarov method. J Pediatr Orthop 2002;22:632-7. (Pubitemid 34966809)
46. Lavy C, Schmidt C, Kalua E, Phuka J. The resistable rise of surgical sepsis in Malawi. Trop Doct 2002;32:98-9. (Pubitemid 34280576)
47. Aird J, Noor S, Lavy C, Rollinson P. The effect of HIV on early wound healing in open fractures treated with internal and external fixation. J Bone Joint Surg [Br] 2011;93-B:678-83.