Oral resveratrol therapy inhibits cancer-induced skeletal muscle and cardiac atrophy in vivo

Nutrition and Cancer

Volumn 63, Issue 5, 2011, Pages 749-762

  Shadfar, Scott ^a   Couch, Marion E ^a,b   McKinney, Kibwei A ^a   Weinstein, Lisa J ^a   Yin, Xiaoying ^a,b   Rodriguez, Jessica E ^a   Guttridge, Denis C ^c   Willis, Monte ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; MESSENGER RNA; RESVERATROL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BODY COMPOSITION; CACHEXIA; CANCER CACHEXIA; CANCER CELL; CANCER INHIBITION; CANCER TRANSPLANTATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DISCRIMINATION; DRUG EXCRETION; DRUG METABOLISM; ECHOCARDIOGRAPHY; ENZYME INHIBITION; FEMALE; GASTROCNEMIUS MUSCLE; HEART FAILURE; HEART MUSCLE; IN VIVO STUDY; MOLECULAR INTERACTION; MOUSE; MUSCLE ATROPHY; MUSCULAR DYSTROPHY; NONHUMAN; PROTEIN DEGRADATION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SARCOMERE; SKELETAL MUSCLE;

ADENOCARCINOMA; ADMINISTRATION, ORAL; ANIMALS; BODY COMPOSITION; CACHEXIA; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ECHOCARDIOGRAPHY; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEART; MICE; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; MYOCARDIUM; NEOPLASM TRANSPLANTATION; RANDOM ALLOCATION; RNA, MESSENGER; STILBENES; TRANSCRIPTION FACTOR RELA; UBIQUITIN-PROTEIN LIGASES; WEIGHT LOSS;

VITACEAE;

EID: 79960591506     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2011.563032     Document Type: Article

References (3)

1. OConnell TM, Ardeshirpour F, Asher SA, Winnike JH, Yin X, et al.: Metabolomic analysis of cancer cachexia reveals distinct lipid and glucose alterations. Metabolomics 4, 216-225, 2008.
2. Acharyya S, Ladner KJ, Nelsen LL, Damrauer J, Reiser PJ, et al.: Cancer cachexia is regulated by selective targeting of skeletal muscle gene products. J Clin Invest 114, 370-378, 2004. (Pubitemid 39071609)
3. Tinsley FC, Taicher GZ, and Heiman ML: Evaluation of a quantitative magnetic resonance method for mouse whole body composition analysis. Obes Res 12, 150-160, 2004. (Pubitemid 41137499)