Limited impact of palliative chemotherapy on survival in advanced solid tumours in patients with poor performance status

Clinical and Translational Oncology

Volumn 13, Issue 6, 2011, Pages 426-429

  Sánchez Muñoz, Alfonso ^a   Pérez Ruiz, Elisabeth ^a   Sáez, María Isabel ^a   Trigo, José Manuel ^a   Galindo, M Mar ^a   Manzaneque, Lourdes ^a   Jiménez, Begoña ^a   Muros, Begoña ^a   Alba, Emilio ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

Author keywords

Advanced solid tumours; Palliative chemotherapy; Poor performance status

Indexed keywords

ANTINEOPLASTIC AGENT;

ACUTE DISEASE; ADOLESCENT; ADULT; ADVANCED CANCER; AGED; ANEMIA; ANOREXIA; ARTICLE; BLOOD DISEASE; BLOOD TOXICITY; CACHEXIA; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER PALLIATIVE THERAPY; CANCER SURVIVAL; CARDIOTOXICITY; COMORBIDITY; CONTROLLED STUDY; DRUG FATALITY; FUNCTIONAL STATUS; HUMAN; LEUKOENCEPHALOPATHY; LIFE EXPECTANCY; LUNG EMBOLISM; MAJOR CLINICAL STUDY; METASTASIS; MULTIPLE CYCLE TREATMENT; NEUTROPENIA; OVERALL SURVIVAL; RETROSPECTIVE STUDY; RISK BENEFIT ANALYSIS; SEPSIS; SOLID TUMOR; SURVIVAL TIME; THROMBOCYTOPENIA;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; FEMALE; FOLLOW-UP STUDIES; HEALTH STATUS INDICATORS; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; PALLIATIVE CARE; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 79960575969     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-011-0677-y     Document Type: Article

References (25)

1. E.J. Emanuel Y. Young-Xu N.G. Levinsky, et al. 2003 Chemotherapy use among Medicare beneficiaries at the end of life Ann Intern Med 138 639 643 12693886
2. C.C. Earle B.A. Neville M.B. Landrum, et al. 2004 Trends in the aggressiveness of cancer care near the end of life J Clin Oncol 22 315 321 14722041 10.1200/JCO.2004.08.136 (Pubitemid 41095097)
3. B. Keam D.Y. Oh S.H. Lee, et al. 2008 Aggressiveness of cancer-care near the end-of-life in Korea Jpn J Clin Oncol 38 381 386 18411260 10.1093/jjco/hyn031 (Pubitemid 351753571)
4. E.B. Lamont N.A. Christakis 2003 Complexities in prognostication in advanced cancer: "to help them live their lives the way they want to" JAMA 290 98 104 12837717 10.1001/jama.290.1.98 (Pubitemid 37432871)
5. M. Maltoni A. Caraceni C. Brunelli, et al. 2005 Prognostic factors in advanced cancer patients: evidence-based clinical recommendations: a study by the Steering Committee of the European Association for Palliative Care J Clin Oncol 23 6240 6248 16135490 10.1200/JCO.2005.06.866
6. W.D. Dewys C. Begg P.T. Lavin, et al. 1980 Prognostic effect of weight loss prior to chemotherapy in cancer patients Eastern Cooperative Oncology Group. Am J Med 69 491 497 1:STN:280:DyaL3M%2Fjs1yhsw%3D%3D (Pubitemid 10018703)
7. M.A. Rosenthal V.J. Gebski R.F. Kefford R.C. Stuart-Harris 1993 Prediction of life expectancy in hospice patients: identification of novel prognostic factors Palliat Med 7 199 204 8261188 10.1177/026921639300700306 1:STN:280:DyaK2c%2FosVeruw%3D%3D (Pubitemid 23217437)
8. M. Maltoni M. Pirovano O. Nanni, et al. 1997 Biological indices predictive of survival in 519 Italian terminally ill cancer patients. Italian Multicenter Study Group on Palliative Care J Pain Symptom Manage 13 1 9 9029856 10.1016/S0885-3924(96)00265-5 1:STN:280:DyaK2s7otFKqtw%3D%3D (Pubitemid 27063350)
9. C.L. Loprinzi J.A. Laurie H.S. Wieand, et al. 1994 Prospective evaluation of prognostic variables from patient-completed questionnaires. North Central Cancer Treatment Group J Clin Oncol 12 601 607 8120560 1:STN:280: DyaK2c7msFKqtQ%3D%3D (Pubitemid 24079905)
10. H.A. Burris M.J. Moore J. Andersen, et al. 1997 Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial J Clin Oncol 15 2403 2413 9196156 1:CAS:528:DyaK2sXlsFKksLY%3D (Pubitemid 27251144)
11. D. Cunningham S. Pyrhönen R.D. James, et al. 1998 Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer Lancet 352 1413 1418 9807987 10.1016/S0140-6736(98)02309-5 1:CAS:528:DyaK1cXnsVSmsLs%3D (Pubitemid 28510874)
12. M.H. Cullen L.J. Billingham C.M. Woodroffe, et al. 1999 Mitomycin, ifosfamide, and cisplatin in unresectable non-small-cell lung cancer: effects on survival and quality of life J Clin Oncol 17 3188 3194 10506617 1:CAS:528:DyaK1MXmslGmtLg%3D (Pubitemid 29470650)
13. F.A. Shepherd J. Dancey R. Ramlau, et al. 2000 Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy J Clin Oncol 18 2095 2103 10811675 1:CAS:528:DC%2BD3cXktVyjsLc%3D (Pubitemid 30324363)
14. C. Doyle M. Crump M. Pintilie A.M. Oza 2001 Does palliative chemotherapy palliate? Evaluation of expectations, outcomes, and costs in women receiving chemotherapy for advanced ovarian cancer J Clin Oncol 19 1266 1274 11230467 1:CAS:528:DC%2BD3MXit1ertrc%3D (Pubitemid 32202529)
15. S.R. Connor B. Pyenson K. Fitch, et al. 2007 Comparing hospice and non-hospice patient survival among patients who die within a three-year window J Pain Symptom Manage 33 238 246 17349493 10.1016/j.jpainsymman.2006.10.010 (Pubitemid 46349540)
16. P. Glare K. Virik M. Jones, et al. 2003 A systematic review of physicians' survival predictions in terminally ill cancer patients BMJ 327 195 198 12881260 10.1136/bmj.327.7408.195 (Pubitemid 36920584)
17. N.A. Christakis E.B. Lamont 2000 Extent and determinants of error in doctors' prognoses in terminally ill patients: prospective cohort study BMJ 320 469 472 10678857 10.1136/bmj.320.7233.469 1:STN:280:DC%2BD3c7ktlKisQ%3D%3D (Pubitemid 30173113)
18. M. Maltoni A. Caraceni C. Brunelli, et al. 2005 Prognostic factors in advanced cancer patients: evidence-based clinical recommendations-a study by the Steering Committee of the European Association for Palliative Care J Clin Oncol 23 6240 6248 16135490 10.1200/JCO.2005.06.866
19. J.W. Mack E.F. Cook J. Wolfe, et al. 2007 Understanding of prognosis among parents of children with cancer: parental optimism and the parent-physician interaction J Clin Oncol 25 1357 1362 17416854 10.1200/JCO.2006.08.3170 (Pubitemid 46706882)
20. S.J. Lee D. Fairclough J.H. Antin, et al. 2001 Discrepancies between patient and physician estimates for the success of stem cell transplantation JAMA 285 1034 1038 11209174 10.1001/jama.285.8.1034 1:STN:280: DC%2BD3M7otlejtA%3D%3D (Pubitemid 32176416)
21. R. Matsuyama S. Reddy T.J. Smith 2006 Why do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancer J Clin Oncol 24 3490 3496 16849766 10.1200/JCO.2005.03.6236 (Pubitemid 46638908)
22. R.C. Smith G.H. Zimny 1988 Physicians' emotional reactions to patients Psychosomatics 29 392 397 3227094 1:STN:280:DyaL1M7ksFCmuw%3D%3D
23. M.L. Slevin L. Stubbs H.J. Plant, et al. 1990 Attitudes to chemotherapy: comparing views of patients with cancer with those of doctors, nurses, and general public BMJ 300 1458 1460 2379006 10.1136/bmj.300.6737.1458 1:STN:280:DyaK3czjsFGjtg%3D%3D (Pubitemid 20195333)
24. C.F. von Gunten 2003 Discussing hospice care J Clin Oncol 21[Suppl9] 31s 36s 10.1200/JCO.2003.01.163
25. H.T. Arkenau D. Olmos J.E. Ang, et al. 2008 90-Day mortality rate in patients treated within the context of a phase-I trial: how should we identify patients who should not go on trial? Eur J Cancer 44 1536 1540 18550361 10.1016/j.ejca.2008.04.017