The modulation of platelet adhesion and activation by chitosan through plasma and extracellular matrix proteins

Biomaterials

Volumn 32, Issue 28, 2011, Pages 6655-6662

  Lord, Megan S ^a   Cheng, Bill ^a   McCarthy, Simon J ^b   Jung, MoonSun ^a   Whitelock, John M ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b HemCon Medical Technologies Inc   (United States)

Author keywords

Chitosan; Integrins; Platelets; Protein adsorption

Indexed keywords

BLOOD LOSS; DATA SUPPORT; EXTRACELLULAR MATRIX PROTEIN; INTEGRINS; P-SELECTIN; PERLECAN; PLATELET ADHESION; PROTEIN ADSORPTION; THROMBUS FORMATION; WOUND CLOSURE; WOUND HEALING;

ADHESION; ADSORPTION; COLLAGEN; GLYCOPROTEINS; PLATELETS;

CHITOSAN;

ALPHA2B INTERFERON; BETA3 INTEGRIN; CHITOSAN; COLLAGEN; FIBRINOGEN; PADGEM PROTEIN; PERLECAN; PLASMA PROTEIN; VERY LATE ACTIVATION ANTIGEN 2;

ADSORPTION; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOGENESIS; WOUND CLOSURE; WOUND HEALING;

ADSORPTION; BLOOD PLATELETS; BLOOD PROTEINS; CHITOSAN; EXTRACELLULAR MATRIX PROTEINS; HUMANS; PLATELET ADHESIVENESS; WOUND HEALING;

EID: 79960564826     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.05.062     Document Type: Article

References (32)

1. Pusateri A.E., McCarthy S.J., Gregory K.W., Harris R.A., Cardenas L., McManus A.T., et al. Effect of a chitosan-based hemostatic dressing on blood loss and survival in a model of severe venous hemorrhage and hepatic injury in swine. J Trauma 2003, 54(1):177-182.
2. Fukasawa M., Abe H., Masaoka T., Orita H., Horikawa H., Campeau J.D., et al. The hemostatic effect of deacetylated chitin membrane on peritoneal injury in rabbit model. Surg Today 1992, 22:333-338.
3. Okamoto Y., Yano R., Miyatake K., Tomohiro I., Shigemasa Y., Minami S. Effects of chitin and chitosan on blood coagulation. Carbohydr Polym 2003, 53:337-342.
4. Janvikul W., Uppanan P., Thavornyutikarn B., Krewraing J., Prateepasen R. In vitro comparative hemostatic studies of chitin, chitosan, and their derivatives. J Appl Polym Sci 2006, 102:445-451.
5. Yang J., Tian F., Wang Z., Wang Q., Zeng Y.-J., Chen S.-Q. Effect of chitosan molecular weight and deacetylation degree on hemostasis. J Biomed Mater Res B 2008, 84B:131-137.
6. Chou T.-C., Fu E., Wu C.-J., Yeh J.-H. Chitosan enhances platelet adhesion and aggregation. Biochem Biophys Res Commun 2003, 302:480-483.
7. Sugamori T., Iwase H., Maeda M., Inoue Y., Kurosawa H. Local hemostatic effects of microcrystalline partially deacetylated chitin hydrochloride. J Biomed Mater Res 2000, 49:225-232.
8. Rao S.B., Sharma C.P. Use of chitosan as a biomaterial: studies on its safety and hemostatic potential. J Biomed Mater Res 1997, 34:21-28.
9. Benesch J., Tengvall P. Blood protein adsorption onto chitosan. Biomaterials 2002, 23:2561-2568.
10. Moroi M., Jung S.M. Platelet receptors for collagen. Thromb Haemost 1997, 78:439-444.
11. Santoro S.A. Identification of a 160,000dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen. Cell 1986, 83:913-920.
12. Nieswandt B., Brakebusch C., Bergmeier W., Schulte V., Bouvard D., Mokhtari-Nejad R., et al. Glycoprotein VI but not α2β1 integrin is essential for platelet interaction with collagen. EMBO J 2001, 20(9):2120-2130.
13. Lord M.S., Yu W., Cheng B., Simmons A., Poole-Warren L., Whitelock J.M. The modulation of platelet and endothelial cell adhesion to vascular graft materials by perlecan. Biomaterials 2009, 30:4898-4906.
14. Ferrell J.E.J., Martin G.S. Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets. Proc Natl Acad Sci U S A 1989, 86:22234-22238.
15. Shattil S.J., Kashiwagi H., Pampori N. Integrin signaling: the platelet paradigm. Blood 1998, 91(8):2645-2657.
16. Nakamura T., Kambayashi J., Okuma M., Tandon N.N. Activation of the GP IIb-IIIa complex induced by platelet adhesion to collagen is mediated by both α2β1 integrin and GP VI. J Biol Chem 1999, 274:11897-11903.
17. Phillips D.R., Charo I.F., Scarborough R.M. GPIIb-IIIa: the responsive integrin. Thromb Res 1991, 65:359-362.
18. Kunicki T.J., Nugent D.J., Staats S.J., Orchekowski R.P., Wayner E.A., Carter W.G. The human fibroblast class II extracellular matrix receptor mediates platelet adhesion to collagen and is identical to the platelet glycoprotein Ia-IIa complex. J Biol Chem 1988, 263:4516-4519.
19. Sonnenberg A., Modderman P.W., Hogervorst F. Laminin receptor on platelets is the integrin VLA-6. Nature 1988, 336:487-489.
20. Wayner E.A., Carter W.G., Piotrowicz R.S., Kunicki T.J. The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion of fibronectin and react with platelet glycoproteins Ic-IIa. J Biol Chem 1988, 107:1881-1891.
21. Plow E.F., McEver R.P., Coller B.S., Woods V.L., Marguerie G.A., Ginsberg M.H. Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor and thrombospondin on thrombin-stimulated human platelets. Blood 1985, 66:724-727.
22. Yeh H.-Y., Lin J.-C. Surface characterisation and in vitro platelet compatibility study of surface sulfonated chitosan membrane with amino group protection-deprotection strategy. J Biomater Sci Polym Ed 2008, 19(3):291-310.
23. Hartwig J.H. Mechanisms of actin rearrangements mediating platelet activation. J Cell Biol 1992, 118(6):1421-1442.
24. Dahlback B., Podack E.R. Characterisation of human S protein, an inhibitor of the membrane attack complex of complement. Demonstration of a free reactive thiol group. Biochemistry 1985, 24(9):2368-2374.
25. Whitelock J.M., Graham L.D., Melrose J., Murdoch A.D., Iozzo R.V., Underwood P.A. Human perlecan immunopurified from different sources has different adhesive properties for vascular cells. Matrix Biol 1999, 18:163-178.
26. Bix G., Iozzo R.A., Woodall B., Burrows M., McQuillan A., Campbell S., et al. Endorepellin, the C-terminal angiostatic module of perlecan, enhanced collagen-platelet responses via the α2β1-integrin receptor. Blood 2007, 109:3745-3748.
27. Tárnok A., Mahnke A., Müller M., Zotz R.J. Rapid in vitro biocompatibility assay of endovascular stents by flow cytometry using platelet activation and platelet-leukocyte aggregation. Cytometry 1999, 38(1):30-39.
28. Lu Q., Malinauskas R.A. Comparison of two platelet activation markers using flow cytometry after in vitro shear stress exposure of whole human blood. Artif Organs 2010, 35(2):137-144.
29. Straub A., Wendel H.P., Azevedo R., Ziemer G. The GP IIb/IIIa inhibitor abciximab (ReoPro) decreases activation and interaction of platelets and leukocytes during in vitro cardiopulmonary bypass stimulation. Eur J Cardio-Thorac 2005, 27:617-621.
30. Merten M., Thiagarajan P. P-selectin expression on platelets determines size and stability of platelet aggregates. Circulation 2000, 102:1931-1936.
31. Banno A., Ginsberg M.H. Integrin activation. Biochem Soc Trans 2008, 36:229-234.
32. Harburger D.S., Bouaouina M., Calderwood D.A. Kindalin-1 and -2 directly bind the C-terminal region of β integrin cytoplasmic tails and exert integrin-specific activation effects. J Biol Chem 2009, 284(17):11485-11497.