High Rates of All-cause and Gastroenteritis-related Hospitalization Morbidity and Mortality among HIV-exposed Indian Infants

BMC Infectious Diseases

Volumn 11, Issue , 2011, Pages

  Singh, Harjot K ^a,f   Gupte, Nikhil ^a   Kinikar, Aarti ^b   Bharadwaj, Renu ^b   Sastry, Jayagowri ^b   Suryavanshi, Nishi ^a   Nayak, Uma ^c   Tripathy, Srikanth ^d   Paranjape, Ramesh ^d   Jamkar, Arun ^e   Bollinger, Robert C ^a   Gupta, Amita ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Byramjee Jeejeebhoy Medical College   (India)

^c UNIVERSITY OF VIRGINIA   (United States)

^d NATIONAL AIDS RESEARCH INSTITUTE   (India)

^e Maharashtra University Health Sciences   (India)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Gastroenteritis; HIV; Hospitalization; In hospital Mortality; India; Infant; pneumonia

Indexed keywords

COTRIMOXAZOLE; NEVIRAPINE;

ADULT; AGE DISTRIBUTION; ARTICLE; BREAST FEEDING; CAUSAL ATTRIBUTION; CHILD; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; GASTROENTERITIS; GESTATIONAL AGE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOSPITAL INFECTION; HOSPITALIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INDIA; INFANT; INFANT MORTALITY; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MORBIDITY; MOTHER CHILD RELATION; RISK FACTOR; SEX DIFFERENCE; VERTICAL TRANSMISSION; VIRUS TRANSMISSION; WEANING; MORTALITY; NEWBORN; PATHOLOGY; PREGNANCY; STATISTICS;

ADULT; FEMALE; GASTROENTERITIS; HIV INFECTIONS; HOSPITALIZATION; HUMANS; INDIA; INFANT; INFANT, NEWBORN; MALE; PREGNANCY;

EID: 79960562699     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-11-193     Document Type: Article

References (27)

1. , . National AIDS Control Organization (NACO), Ministry of Women and Child Health, Government of India, UNICEF Policy framework for children and AIDS: India 2007, National AIDS Control Organization (NACO), Ministry of Women and Child Health, Government of India, UNICEF.
2. . Regional Office for South-East Asia, World Health Organization Improving Maternal Newborn and Child Health-India Last accessed March 3, 2010, Regional Office for South-East Asia, World Health Organization., http://www.searo.who.int/LinkFiles/Improving_maternal_newborn_and_child_health_india.pdf
3. National AIDS Control Organization (NACO) Note on HIV Sentinel Surveillance and HIV Estimation 2008, Last accessed June 14, 2010, National AIDS Control Organization (NACO)., http://www.nacoonline.org/upload/NACO%20PDF/Note%20on%20HIV%20Sentinel%20Surveillance%20and%20HIV%20Estimation_01%20Feb%2008.pdf
4. Mbori-Ngacha D, Nduati R, John G, Reilly M, Richardson B, Mwatha A, Ndinya-Achola J, Bwayo J, Kreiss J. Morbidity and Mortality in Breastfed and Formula-fed Infants of HIV-1-infected Women: A Randomized Clinical Trial. JAMA 2001, 286(19):2413-2420. 10.1001/jama.286.19.2413, 11712936.
5. Becquet R, Bequet L, Ekouevi DK, Viho I, Sakarovitch C, Fassinou P, Bedikou G, Timite-Konan M, Dabis F, Leroy V, . ANRS 1201/1202 Ditrame Plus Study Group Two-Year Morbidity-Mortality and Alternatives to Prolonged Breast-Feeding among Children Born to HIV-Infected Mothers in Cote D'Ivoire. PLoS Med 2007, 4(1):e17. 10.1371/journal.pmed.0040017, 1769413, 17227132, ANRS 1201/1202 Ditrame Plus Study Group.
6. Madhi SA, Petersen K, Madhi A, Khoosal M, Klugman KP. Increased Disease Burden And Antibiotic Resistance of Bacteria Causing Severe Community-Acquired Lower Respiratory Tract Infections in Human Immunodeficiency Virus Type 1-Infected Children. Clin Infect Dis 2000, 31(1):170-176. 10.1086/313925, 10913417.
7. Marinda E, Humphrey JH, Iliff PJ, Mutasa K, Nathoo KJ, Piwoz EG, Moulton LH, Salama P, Ward BJ, . ZVITAMBO Study Group Child Mortality According to Maternal and Infant HIV Status in Zimbabwe. Pediatr Infect Dis J 2007, 26(6):519-26. 10.1097/01.inf.0000264527.69954.4c, 17529870, ZVITAMBO Study Group.
8. Kuhn L, Kasonde P, Sinkala M, Kankasa C, Semrau K, Scott N, Tsai WY, Vermund SH, Aldrovandi GM, Thea DM. Does Severity of HIV Disease in HIV-Infected Mothers Affect Mortality and Morbidity among Their Uninfected Infants?. Clin Infect Dis 2005, 41(11):1654-1661. 10.1086/498029, 1351118, 16267740.
9. Mussi-Pinhata MM, Freimanis L, Yamamoto AY, Korelitz J, Pinto JA, Cruz ML, Losso MH, Read JS, . National Institute of Child Health and Human Development International Site Development Initiative Perinatal Study Group Infectious Disease Morbidity Among Young HIV-1-Exposed But Uninfected Infants in Latin American And Caribbean Countries: The National Institute of Child Health And Human Development International Site Development Initiative Perinatal Study. Pediatrics 2005, 119(3):e694-704. National Institute of Child Health and Human Development International Site Development Initiative Perinatal Study Group.
10. Bryce J, Boschi-Pinto C, Shibuya K, Black RE, . WHO Child Health Epidemiology Reference Group WHO estimates of the Causes of Death in Children. Lancet 2005, 365(9465):1147-1152. 10.1016/S0140-6736(05)71877-8, 15794969, WHO Child Health Epidemiology Reference Group.
11. Singh HK, Gupta A, Siberry GK, Gupte N, Sastry J, Kinikar A, Shah I, Gangakhedkar RR, Bollinger RC, Kulkarni V. The Indian Pediatric HIV Epidemic: A Systematic Review. Curr HIV Res 2008, 6(5):419-32. 10.2174/157016208785861203, 18855652.
12. Bedri A, Gudetta B, Isehak A, Kumbi S, Lulseged S, Mengistu Y, Bhore AV, Bhosale R, Varadhrajan V, Gupte N, Sastry J, Suryavanshi N, Tripathy S, Mmiro F, Mubiru M, Onyango C, Taylor A, Musoke P, Nakabiito C, Abashawl A, Adamu R, Antelman G, Bollinger RC, Bright P, Chaudhary MA, Coberly J, Guay L, Fowler MG, Gupta A, Hassen E, Jackson JB, Moulton LH, Nayak U, Omer SB, Propper L, Ram M, Rexroad V, Ruff AJ, Shankar A, Zwerski S. Six Week Extended-Dose Nevirapine (SWEN) Study Team Extended-Dose Nevirapine to 6 Weeks of Age for Infants to Prevent HIV Transmission Via Breastfeeding in Ethiopia, India, and Uganda: an Analysis of Three Randomised Controlled Trials. Lancet 2008, 372(9635):300-313. Six Week Extended-Dose Nevirapine (SWEN) Study Team.
13. Rapid advice. Use of Antiviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants 2009, Last accessed May 10, 2010., http://www.searo.who.int/LinkFiles/HIV-AIDS_Rapid_Advice_MTCT(web).pdf
14. World Health Organization Interim WHO clinical staging of HIV/AIDS and HIV/AIDS case definitions for surveillance 2005, Last accessed August 1, 2010, World Health Organization., http://www.who.int/hiv/pub/guidelines/clinicalstaging.pdf
15. World Health Organization Guidelines on Co-trimoxazole Prophylaxis for HIV-related Infections among Children, Adolescents, and Adults Recommendations for a Public Health Approach Last accessed September 20, 2009, World Health Organization., http://www.who.int/hiv/pub/guidelines/ctx/en/index.html
16. , . World Health Organization, UNICEF, UNAIDS, UNFPA HIV and Infant Feeding: Update. Based on the Technical Consultation Held on Behalf of the Inter-Agency Task Team (IATT) On Prevention of HIV Infection in Pregnant Women, Mothers and their InfantsGeneva, Switzerland25-27 October 2006http://whqlibdoc.who.int/publications/2007/9789241595964_eng.pdf, Last accessed September 1, 2010, World Health Organization, UNICEF, UNAIDS, UNFPA.
17. World Health Organization Global burden of disease (GBD) study 2000-2002: GBD Sequelae and Case Definitions. Iron Deficiency Anemia Last accessed on August 1, 2010, World Health Organization.
18. STATA StataCorp. 2001. Statistical software: Release 10.0. College Station, TX: Stata Corporation, STATA.
19. Meyers TM, Pettifor JM, Gray GE, Crewe-Brown H, Galpin JS. Pediatric Admissions with Human Immunodeficiency Virus Infection at a Regional Hospital in Soweto, South Africa. J Trop Pediatr 2000, 46(4):224-230. 10.1093/tropej/46.4.224, 10996984.
20. Venkatesh KK, de Bruyn G, Marinda E, Otwombe K, van Niekerk R, Urban M, Triche EW, McGarvey ST, Lurie MN, Gray GE. Morbidity and Mortality among Infants Born to HIV-infected Women in South Africa: Implications for Child Health in Resource-limited Settings. J Trop Pediatr 2010,
21. Kafulafula G, Thigpen M, Hoover D, et al. 14th Conference on Retroviruses and Opportunistic Infections.2007. Poster 773. Post-weaning Gastroenteritis and Mortality in HIV-uninfected African Infants Receiving Antiretroviral Prophylaxis to Prevent MTCT of HIV-1
22. Suryavanshi N, Jonnalagadda S, Erande AS, Sastry J, Pisal H, Bharucha KE, Shrotri A, Bulakh PM, Phadke MA, Bollinger RC, Shankar AV. Infant Feeding Practices of HIV-positive Mothers in India. J Nutr 2005, 133(5):1326-1331.
23. Shankar AV, Sastry J, Erande A, Joshi A, Suryawanshi N, Phadke MA, Bollinger RC. Making the Choice: The Translation of Global HIV and Infant Feeding Policy to Local Practice Among Mothers in Pune, India. J Nutr 2005, 135(4):960-965.
24. Kuhn L, Aldrovandi GM, Sinkala M, Kankasa C, Semrau K, Mwiya M, Kasonde P, Scott N, Vwalika C, Walter J, Bulterys M, Tsai WY, Thea DM, . Zambia Exclusive Breastfeeding Study Effects of Early, Abrupt Weaning on HIV-free Survival of Children in Zambia. N Engl J Med 2005, 359(2):130-141. Zambia Exclusive Breastfeeding Study.
25. World Health Organization Key messages: New WHO Recommendations: Infant feeding in the context of HIV Last accessed June 5, 2010, World Health Organization., http://www.who.int/hiv/pub/paediatric/infant_key_mess.pdf
26. Zwi K, Pettifor J, Soderlund N, Meyers T. HIV Infection and In-Hospital Mortality at an Academic Hospital in South Africa. Arch Dis Child 2000, 83(3):227-230. 10.1136/adc.83.3.227, 1718469, 10952640.
27. Drevenstedt GL, Crimmins EM, Vasunilashorn S, Finch CE. The Rise and Fall of Excess Male Infant Mortality. Proc Natl Acad Sci 2008, 105(13):5016-21. USA, 10.1073/pnas.0800221105, 2278210, 18362357.