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Volumn 19, Issue 15, 2011, Pages 4616-4625
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Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy) propyl]nucleoside alkoxyalkyl esters: Inhibitors of hepatitis C virus and HIV-1 replication
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Author keywords
Alkoxyalkyl prodrugs; Antiviral prodrugs; Hepatitis C virus; Human immunodeficiency virus 1; Nucleoside phosphonate prodrugs
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Indexed keywords
2,6 DIAMINOPURINE DERIVATIVE;
4' AZIDOCYTIDINE;
9 [(3 ALKOXY 2 HYDROXY)PROPYL]DERIVATIVE;
9 [(3 ETHOXY 2 HYDROXY)PROPYL] 2,6 DIAMINOPURINE;
9 [(3 ETHOXY 2 HYDROXY)PROPYL] 6 O BENZYLGUANINE;
9 [(3 ETHOXY 2 HYDROXY)PROPYL]ADENINE;
9 [(3 ISOPROPOXY 2 HYDROXY)PROPYL]ADENINE;
9 [(3 METHOXY 2 HYDROXY)PROPYL] 2,6 DIAMINOPURINE;
9 [(3 METHOXY 2 HYDROXY)PROPYL] 6 O BENZYLGUANINE;
9 [(3 METHOXY 2 HYDROXY)PROPYL]ADENINE;
9 [3 ALKOXY 2 (PHOSPHONOMETHOXY)PROPYL]NUCLEOSIDE ALKOXYALKYL ESTER;
9 [3 HYDROXYOXY 2 (PHOSPHONOMETHOXY)PROPYL]ADENINE;
ACYCLIC NUCLEOSIDE;
ALKOXYALKYL 9 [(3 ALKOXY 2 PHOSPHONOMETHOXY)PROPYL]ADENINE;
ALKOXYALKYL 9 [(3 ALKOXY 2 PHOSPHONOMETHOXY)PROPYL]GUANINE;
ANTIVIRUS AGENT;
GUANINE DERIVATIVE;
HEXADECYLOXYETHYL 9 [(3 ETHOXY 2 PHOSPHONOMETHOXY)PROPYL]ADENINE;
HEXADECYLOXYETHYL 9 [(3 ISOPROPOXY 2 PHOSPHONOMETHOXY)PROPYL]ADENINE;
HEXADECYLOXYPROPYL 9 [(3 ETHOXY 2 PHOSPHONOMETHOXY)PROPYL] 2,6 DIAMINOPURINE;
HEXADECYLOXYPROPYL 9 [(3 ETHOXY 2 PHOSPHONOMETHOXY)PROPYL]GUANINE;
HEXADECYLOXYPROPYL 9 [(3 METHOXY 2 PHOSPHONOMETHOXY)PROPYL] 2,6 DIAMINOPURINE;
HEXADECYLOXYPROPYL 9 [(3 METHOXY 2 PHOSPHONOMETHOXY)PROPYL]GUANINE;
HEXADECYLOXYPROPYL 9 [3 ETHOXY 2 (PHOSPHONOMETHOXY)PROPYL]ADENINE;
HEXADECYLOXYPROPYL 9 [3 METHOXY 2 (PHOSPHONOMETHOXY)PROPYL]ADENINE;
OCTADECYLOXYETHYL 9 [(3 METHOXY 2 PHOSPHONOMETHOXY)PROPYL] 2,6 DIAMINOPURINE;
OCTADECYLOXYETHYL 9 [(3 METHOXY 2 PHOSPHONOMETHOXY)PROPYL] 6 O BENZYLGUANINE;
OCTADECYLOXYETHYL 9 [(3 METHOXY 2 PHOSPHONOMETHOXY)PROPYL]GUANINE;
OCTADECYLOXYETHYL 9 [3 METHOXY 2 (PHOSPHONOMETHOXY)PROPYL]ADENINE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ANTIVIRAL ACTIVITY;
ARTICLE;
DRUG CYTOTOXICITY;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HEPATITIS C;
HEPATITIS C VIRUS;
HUMAN IMMUNODEFICIENCY VIRUS 1;
HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION;
MASS SPECTROMETRY;
PROTON NUCLEAR MAGNETIC RESONANCE;
REPLICON;
VIRUS REPLICATION;
ADENINE;
ANTIVIRAL AGENTS;
HEPACIVIRUS;
HEPATITIS C;
HIV INFECTIONS;
HIV-1;
HUMANS;
PHOSPHONIC ACIDS;
PRODRUGS;
VIRUS REPLICATION;
DNA VIRUSES;
HEPATITIS B VIRUS;
HEPATITIS C VIRUS;
HUMAN IMMUNODEFICIENCY VIRUS 1;
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EID: 79960559670
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2011.06.009 Document Type: Article |
Times cited : (13)
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References (25)
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