Reduction of infarct size by intravenous injection of uncultured adipose derived stromal cells in a rat model is dependent on the time point of application

Stem Cell Research

Volumn 7, Issue 3, 2011, Pages 219-229

  Van Dijk, A ^a,b   Naaijkens, B A ^a,b   Jurgens, W J F M ^a   Nalliah, K ^a   Sairras, S ^a   van der Pijl, R J ^a   Vo, K ^a   Vonk, A B A ^a   van Rossum, A C ^a   Paulus, W J ^a   van Milligen, F J ^a   Niessen, H W M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Technology Foundation   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE HEART INFARCTION; ADIPOSE DERIVED STROMAL CELL; ADIPOSE TISSUE CELL; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DYSPNEA; HEART; HEART INFARCTION; HEART INFARCTION SIZE; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL TRANSPLANTATION; STROMA CELL; STROMAL VASCULAR FRACTION; TREATMENT OUTCOME; WISTAR RAT;

ADIPOSE TISSUE; ANIMALS; BIOLOGICAL MARKERS; BLOOD VESSELS; CELL COUNT; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HEART FUNCTION TESTS; INJECTIONS, INTRAVENOUS; MACROPHAGES; MALE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; STEM CELL TRANSPLANTATION; STEM CELLS; STROMAL CELLS; THROMBOEMBOLISM; TIME FACTORS;

ANIMALIA; RATTUS;

EID: 79960556913     PISSN: 18735061     EISSN: 18767753     Source Type: Journal    
DOI: 10.1016/j.scr.2011.06.003     Document Type: Article

References (40)

1. Andrade W., Seabrook T.J., Johnston M.G., Hay J.B. The use of the lipophilic fluorochrome CM-DiI for tracking the migration of lymphocytes. J. Immunol. Methods 1996, 194:181-189.
2. Azarnoush K. Enhancement of the functional benefits of skeletal myoblast transplantation by means of coadministration of hypoxia-inducible factor 1alpha 2005.
3. Azarnoush K., Maurel A., Sebbah L., Carrion C., Bissery A., Mandet C., Pouly J., Bruneval P., Hagege A.A., Menasche P. Enhancement of the functional benefits of skeletal myoblast transplantation by means of coadministration of hypoxia-inducible factor 1alpha. J. Thorac. Cardiovasc. Surg. 2005, 130:173-179.
4. Bai X., Yan Y., Song Y.H., Seidensticker M., Rabinovich B., Metzele R., Bankson J.A., Vykoukal D., Alt E. Both cultured and freshly isolated adipose tissue-derived stem cells enhance cardiac function after acute myocardial infarction. Eur. Heart J. 2010, 31:489-501.
5. Bermejo J., Segovia J., Alfonso F. Summary of the clinical studies reported in the scientific session of the American Heart Association 2005 (Dallas, Texas, USA, 13-16 November 2005). Rev. Esp. Cardiol. 2006, 59:143-153.
6. Gao J., Dennis J.E., Muzic R.F., Lundberg M., Caplan A.I. The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues. Organs 2001, 169:12-20.
7. Gaustad K.G., Boquest A.C., Anderson B.E., Gerdes A.M., Collas P. Differentiation of human adipose tissue stem cells using extracts of rat cardiomyocytes. Biochem. Biophys. Res. Commun. 2004, 314:420-427.
8. Guo J. Anti-Inflammation Role for Mesenchymal Stem Cells Transplantation in Myocardial Infarction 2007.
9. Jiang C.Y., Gui C., He A.N., Hu X.Y., Chen J., Jiang Y., Wang J.A. Optimal time for mesenchymal stem cell transplantation in rats with myocardial infarction. J. Zhejiang Univ Sci. B 2008, 9:630-637.
10. Lee R.J., Fang Q., Davol P.A., Gu Y., Sievers R.E., Grabert R.C., Gall J.M., Tsang E., Yee M.S., Fok H., Huang N.F., Padbury J.F., Larrick J.W., Lum L.G. Antibody targeting of stem cells to infarcted myocardium. Stem Cells 2007, 25:712-717.
11. Lu L., Zhang J.Q., Ramires F.J., Sun Y. Molecular and cellular events at the site of myocardial infarction: from the perspective of rebuilding myocardial tissue. Biochem. Biophys. Res. Commun. 2004, 320:907-913.
12. Ma J. Time course of myocardial stromal cell-derived factor 1 expression and beneficial effects of intravenously administered bone marrow stem cells in rats with experimental myocardial infarction 2005.
13. Malek S., Kaplan E., Wang J.F., Ke Q., Rana J.S., Chen Y., Rahim B.G., Li M., Huang Q., Xiao Y.F., Verheugt F.W., Morgan J.P., Min J.Y. Successful implantation of intravenously administered stem cells correlates with severity of inflammation in murine myocarditis. Pflugers Arch. 2006, 452:268-275.
14. Mazo M., Planat-Benard V., Abizanda G., Pelacho B., Leobon B., Gavira J.J., Penuelas I., Cemborain A., Penicaud L., Laharrague P., Joffre C., Boisson M., Ecay M., Collantes M., Barba J., Casteilla L., Prosper F. Transplantation of adipose derived stromal cells is associated with functional improvement in a rat model of chronic myocardial infarction. Eur. J. Heart Fail. 2008, 10:454-462.
15. McIntosh K., Zvonic S., Garrett S., Mitchell J.B., Floyd Z.E., Hammill L., Kloster A., Di H.Y., Ting J.P., Storms R.W., Goh B., Kilroy G., Wu X., Gimble J.M. The immunogenicity of human adipose-derived cells: temporal changes in vitro. Stem Cells 2006, 24:1246-1253.
16. Meliga E., Strem B.M., Duckers H.J., Serruys P.W. Adipose-derived cells. Cell Transplant. 2007, 16:963-970.
17. Min J.Y., Huang X., Xiang M., Meissner A., Chen Y., Ke Q., Kaplan E., Rana J.S., Oettgen P., Morgan J.P. Homing of intravenously infused embryonic stem cell-derived cells to injured hearts after myocardial infarction. J. Thorac. Cardiovasc. Surg. 2006, 131:889-897.
18. Miyahara Y., Nagaya N., Kataoka M., Yanagawa B., Tanaka K., Hao H., Ishino K., Ishida H., Shimizu T., Kangawa K., Sano S., Okano T., Kitamura S., Mori H. Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction. Nat. Med. 2006, 12:459-465.
19. Moreb J.S. Aldehyde dehydrogenase as a marker for stem cells. Curr. Stem Cell Res. Ther. 2008, 3:237-246.
20. Ndrepepa G., Mehilli J., Martinoff S., Schwaiger M., Schomig A., Kastrati A. Evolution of left ventricular ejection fraction and its relationship to infarct size after acute myocardial infarction. J. Am. Coll. Cardiol. 2007, 50:149-156.
21. Oedayrajsingh-Varma M.J., van Ham S.M., Knippenberg M., Helder M.N., Klein-Nulend J., Schouten T.E., Ritt M.J., van Milligen F.J. Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure. Cytotherapy 2006, 8:166-177.
22. Orlic D., Kajstura J., Chimenti S., Limana F., Jakoniuk I., Quaini F., Nadal-Ginard B., Bodine D.M., Leri A., Anversa P. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc. Natl. Acad. Sci. USA 2001, 98:10344-10349.
23. Pfeffer M.A., Pfeffer J.M., Fishbein M.C., Fletcher P.J., Spadaro J., Kloner R.A., Braunwald E. Myocardial infarct size and ventricular function in rats. Circ. Res. 1979, 44:503-512.
24. Rangappa S., Fen C., Lee E.H., Bongso A., Sim E.K. Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes. Ann. Thorac. Surg. 2003, 75:775-779.
25. Rombouts W.J., Ploemacher R.E. Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture. Leukemia 2003, 17:160-170.
26. Sadat S., Gehmert S., Song Y.H., Yen Y., Bai X., Gaiser S., Klein H., Alt E. The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF. Biochem. Biophys. Res. Commun. 2007, 363:674-679.
27. Schaer G.L., Karas S.P., Santoian E.C., Gold C., Visner M.S., Virmani R. Reduction in reperfusion injury by blood-free reperfusion after experimental myocardial infarction. J. Am. Coll. Cardiol. 1990, 15:1385-1393.
28. Singla D.K. Factors Released from Embryonic Stem Cells Inhibit Apoptosis of H9c2 Cells 2007.
29. Strem B.M., Zhu M., Alfonso Z., Daniels E.J., Schreiber R., Beygui R., MacLellan W.R., Hedrick M.H., Fraser J.K. Expression of cardiomyocytic markers on adipose tissue-derived cells in a murine model of acute myocardial injury. Cytotherapy 2005, 7:282-291.
30. Uemura R., Xu M., Ahmad N., Ashraf M. Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling. Circ. Res. 2006, 98:1414-1421.
31. Valina C., Pinkernell K., Song Y.H., Bai X., Sadat S., Campeau R.J., Le Jemtel T.H., Alt E. Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarction. Eur. Heart J. 2007, 28:2667-2677.
32. van Dijk A., Niessen H.W., Ursem W., Twisk J.W., Visser F.C., van Milligen F.J. Accumulation of fibronectin in the heart after myocardial infarction: a putative stimulator of adhesion and proliferation of adipose-derived stem cells. Cell Tissue Res. 2008, 332:289-298.
33. van Dijk A., Niessen H.W., Zandieh D.B., Visser F.C., van Milligen F.J. Differentiation of human adipose-derived stem cells towards cardiomyocytes is facilitated by laminin. Cell Tissue Res. 2008, 334:457-467.
34. van Dijk A., Krijnen P.A., Vermond R.A., Pronk A., Spreeuwenberg M., Visser F.C., Berney R., Paulus W.J., Hack C.E., van Milligen F.J., Niessen H.W. Inhibition of type 2A secretory phospholipase A2 reduces death of cardiomyocytes in acute myocardial infarction. Apoptosis 2009, 14:753-763.
35. Wang Q.D., Sjoquist P.O. Myocardial regeneration with stem cells: pharmacological possibilities for efficacy enhancement. Pharmacol. Res. 2006, 53:331-340.
36. Weir C., Morel-Kopp M.C., Gill A., Tinworth K., Ladd L., Hunyor S.N., Ward C. Mesenchymal stem cells: isolation, characterisation and in vivo fluorescent dye tracking. Heart Lung Circ. 2008, 17:395-403.
37. Wolf D., Reinhard A., Seckinger A., Katus H.A., Kuecherer H., Hansen A. Dose-dependent effects of intravenous allogeneic mesenchymal stem cells in the infarcted porcine heart. Stem Cells Dev. 2009, 18:321-329.
38. Zhang D.Z., Gai L.Y., Liu H.W., Jin Q.H., Huang J.H., Zhu X.Y. Transplantation of autologous adipose-derived stem cells ameliorates cardiac function in rabbits with myocardial infarction. Chin. Med. J. (Engl.) 2007, 120:300-307.
39. Zhu Y., Liu T., Song K., Fan X., Ma X., Cui Z. Adipose-derived stem cell: a better stem cell than BMSC. Cell Biochem. Funct. 2008, 26:664-675.
40. Zuk P.A., Zhu M., Ashjian P., De Ugarte D.A., Huang J.I., Mizuno H., Alfonso Z.C., Fraser J.K., Benhaim P., Hedrick M.H. Human adipose tissue is a source of multipotent stem cells. Mol. Biol. Cell 2002, 13:4279-4295.