Dynamic postprandial hepatic stiffness augmentation assessed with MR elastography in patients with chronic liver disease

American Journal of Roentgenology

Volumn 197, Issue 1, 2011, Pages 64-70

  Yin, Meng ^a   Talwalkar, Jayant A ^a   Glaser, Kevin J ^a   Venkatesh, Sudhakar K ^a,b   Chen, Jun ^a   Manduca, Armando ^a   Ehman, Richard L ^a  

^a MAYO CLINIC   (United States)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Hepatic stiffness; MR elastography; Perfusion; Postprandial augmentation

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELASTOGRAPHY; FEMALE; HUMAN; IMAGE ANALYSIS; LIVER DISEASE; LIVER FIBROSIS; LIVER STIFFNESS; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PORTAL HYPERTENSION; PORTAL VEIN BLOOD PRESSURE; POSTPRANDIAL STATE; PRIORITY JOURNAL; TEST MEAL;

ADULT; AGED; ELASTIC MODULUS; ELASTICITY IMAGING TECHNIQUES; FEMALE; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; POSTPRANDIAL PERIOD; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 79960528757     PISSN: 0361803X     EISSN: 15463141     Source Type: Journal    
DOI: 10.2214/AJR.10.5989     Document Type: Article

References (34)

1. Schuppan D, Popov Y. Hepatic fibrosis: from bench to bedside. J Gastroenterol Hepatol 2002; 17[suppl 3]:S300-S305 (Pubitemid 35454302)
2. Zhou K, Lu LG. Assessment of fibrosis in chronic liver diseases. J Dig Dis 2009; 10:7-14
3. Sandrin L, Fourquet B, Hasquenoph JM, et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med Biol 2003; 29:1705-1713 (Pubitemid 38091720)
4. Taura T, Nakamura K, Takashima S, et al. Heterogeneity of hepatic parenchymal enhancement on computed tomography during arterial portography: quantitative analysis of correlation with severity of hepatic fibrosis. Hepatol Res 2001; 20: 182-192
5. Faria SC, Ganesan K, Mwangi I, et al. MR imaging of liver fibrosis: current state of the art. Radio-Graphics 2009; 29:1615-1635
6. Muthupillai R, Lomas DJ, Rossman PJ, Greenleaf JF, Manduca A, Ehman RL. Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. Science 1995; 269: 1854-1857
7. Asbach P, Klatt D, Hamhaber U, et al. Assessment of liver viscoelasticity using multifrequency MR elastography. Magn Reson Med 2008; 60:373-379
8. Yin M, Talwalkar JA, Glaser KJ, et al. Assessment of hepatic fibrosis with magnetic resonance elastography. Clin Gastroenterol Hepatol 2007; 5:1207-1213
9. Huwart L, van Beers BE. MR elastography. Gastroenterol Clin Biol 2008; 32:68-72
10. Lupsor M, Badea R, Stefanescu H, et al. Analysis of histopathological changes that influence liver stiffness in chronic hepatitis C: results from a cohort of 324 patients. J Gastrointestin Liver Dis 2008; 17:155-163 (Pubitemid 351930761)
11. Castera L, Foucher J, Bernard PH, et al. Pitfalls of liver stiffness measurement: a 5-year prospective study of 13,369 examinations. Hepatology 2010; 51:828-835
12. Bensamoun SF, Wang L, Robert L, Charleux F, Latrive JP, Ho Ba Tho MC. Measurement of liver stiffness with two imaging techniques: magnetic resonance elastography and ultrasound elastometry. J Magn Reson Imaging 2008; 28:1287-1292
13. Adhoute X, Foucher J, Laharie D, et al. Diagnosis of liver fibrosis using FibroScan and other noninvasive methods in patients with hemochromatosis: a prospective study. Gastroenterol Clin Biol 2008; 32:180-187 (Pubitemid 351635694)
14. Salameh N, Larrat B, Abarca-Quinones J, et al. Early detection of steatohepatitis in fatty rat liver by using MR elastography. Radiology 2009; 253:90-97
15. Roulot D, Czernichow S, Le Clesiau H, Costes JL, Vergnaud AC, Beaugrand M. Liver stiffness values in apparently healthy subjects: influence of gender and metabolic syndrome. J Hepatol 2008; 48:606-613
16. Talwalkar JA, Yin M, Venkatesh S, et al. Feasibility of in vivo MR elastographic splenic stiffness measurements in the assessment of portal hypertension. AJR 2009; 193:122-127
17. Ahuja KD, Robertson IK, Ball MJ. Acute effects of food on postprandial blood pressure and measures of arterial stiffness in healthy humans. Am J Clin Nutr 2009; 90:298-303
18. Parker DR, Carlisle K, Cowan FJ, Corrall RJ, Read AE. Postprandial mesenteric blood flow in humans: relationship to endogenous gastrointestinal hormone secretion and energy content of food. Eur J Gastroenterol Hepatol 1995; 7:435-440
19. Hines CD, Bley TA, Lindstrom MJ, Reeder SB. Repeatability of magnetic resonance elastography for quantification of hepatic stiffness. J Magn Reson Imaging 2010; 31:725-731
20. Mederacke I, Wursthorn K, Kirschner J, et al. Food intake increases liver stiffness in patients with chronic or resolved hepatitis C virus infection. Liver Int 2009; 29:1500-1506
21. Yin M, Chen J, Glaser KJ, Talwalkar JA, Ehman RL. Abdominal magnetic resonance elastography. Top Magn Reson Imaging 2009; 20:79-87
22. Manduca A, Oliphant TE, Dresner MA, et al. Magnetic resonance elastography: non-invasive mapping of tissue elasticity. Med Image Anal 2001; 5:237-254 (Pubitemid 35282809)
23. O'Brien S, Keogan M, Patchett S, McCormick PA, Afdhal N, Hegarty JE. Postprandial changes in portal haemodynamics in patients with cirrhosis. Gut 1992; 33:364-367
24. Siringo S, Piscaglia F, Zironi G, et al. Influence of esophageal varices and spontaneous portal-systemic shunts on postprandial splanchnic hemodynamics. Am J Gastroenterol 2001; 96:550-556
25. Ludwig D, Schwarting K, Korbel CM, Bruning A, Schiefer B, Stange EF. The postprandial portal flow is related to the severity of portal hypertension and liver cirrhosis. J Hepatol 1998; 28:631-638 (Pubitemid 28168001)
26. Sabba C, Ferraioli G, Genecin P, et al. Evaluation of postprandial hyperemia in superior mesenteric artery and portal vein in healthy and cirrhotic humans: an operator-blind echo-Doppler study. Hepatology 1991; 13:714-718
27. Someya N, Endo MY, Fukuba Y, Hayashi N. Blood flow responses in celiac and superior mesenteric arteries in the initial phase of digestion. Am J Physiol 2008; 294:R1790-R1796
28. Zardi EM, Dobrina A, Uwechie V, et al. Postmeal portal flow variations in HCV-related chronic hepatitis and liver cirrhosis with and without hyperdynamic syndrome. In Vivo 2008; 22:509-512
29. Ozdogan O, Atalay H, Cimsit C, et al. Role of echo Doppler ultrasonography in the evaluation of postprandial hyperemia in cirrhotic patients. World J Gastroenterol 2008; 14:260-264
30. Millonig G, Friedrich S, Adolf S, et al. Liver stiffness is directly influenced by central venous pressure. J Hepatol 2010; 52:206-210
31. Albillos A, Banares R, Gonzalez M, et al. The extent of the collateral circulation influences the postprandial increase in portal pressure in patients with cirrhosis. Gut 2007; 56:259-264
32. Wicklein S, Muhlberg W, Richter B, Sieber CC. Increased splanchnic arterial vascular resistance in oldest old patients: possible relevance for post-prandial hypotension. Z Gerontol Geriatr 2007; 40:37-42
33. Wells RG. The role of matrix stiffness in hepatic stellate cell activation and liver fibrosis. J Clin Gastroenterol 2005; 39[4 suppl 2]:S158-S161 (Pubitemid 40397030)
34. Georges PC, Hui JJ, Gombos Z, et al. Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis. Am J Physiol Gastrointest Liver Physiol 2007; 293:G1147-G1154 (Pubitemid 350255055)